3-Acetyl-2-bromopyridine
- Product Name
- 3-Acetyl-2-bromopyridine
- CAS No.
- 84199-61-1
- Chemical Name
- 3-Acetyl-2-bromopyridine
- Synonyms
- 3-ACETYL-2-BROMOPYRIDINE;1-(2-Bromo-3-pyridyl)ethanone;1-(2-Bromo-3-pyridinyl)ethanone;3-(2-Bromopyridyl) methyl ketone;1-(2-BROMO-PYRIDIN-3-YL)-ETHANONE;1-(2-broMopyridin-3-yl)ethan-1-one;Ethanone, 1-(2-bromo-3-pyridinyl)-;3-Acetyl-2-bromopyridine ISO 9001：2015 REACH
- CBNumber
- CB3401246
- Molecular Formula
- C7H6BrNO
- Formula Weight
- 200.03
- MOL File
- 84199-61-1.mol
3-Acetyl-2-bromopyridine Property
- Boiling point:
- 115 °C(Press: 7 Torr)
- Density
- 1.552 g/mL at 25 °C
- refractive index
- n20/D1.572
- Flash point:
- >110℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- liquid
- pka
- -1.01±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- WGK Germany
- 1
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 706701
- Product name
- 3-Acetyl-2-bromopyridine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $298
- Updated
- 2023/06/20
- Product number
- A168055
- Product name
- 3-Acetyl-2-bromopyridine
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- FA51213
- Product name
- 3-Acetyl-2-bromopyridine
- Packaging
- 250mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 073528
- Product name
- 3-Acetyl-2-bromopyridine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $278
- Updated
- 2021/12/16
- Product number
- FA51213
- Product name
- 3-Acetyl-2-bromopyridine
- Packaging
- 500mg
- Price
- $175
- Updated
- 2021/12/16
3-Acetyl-2-bromopyridine Chemical Properties,Usage,Production
Uses
3-Acetyl-2-bromopyridine is a chemical reagent used in nonquaternary reactivators of GF-inhibited human acetylcholinesterase. Also used in the synthesis of HIV-1 reverse transriptase inhibitors.
Synthesis
84199-57-5
84199-61-1
GENERAL METHOD: CrO3 (33.1 g, 0.331 mol) was slowly added in small portions to a solution of 1-(2-bromopyridin-3-yl)ethanol (30.5 g, 0.133 mol) in acetone (350 mL). The reaction mixture was stirred at room temperature for 18 hours. The solvent was evaporated under reduced pressure and hexane (1 L) was added, followed by a solution of NaOH (26.5 g, 0.662 mol) in water (150 mL). The mixture was stirred for 30 min. The organic layer was separated, dried with Na2SO4, filtered through a silica gel pad (40 g) and evaporated under reduced pressure.
References
[1] Journal of Chemical Research, Miniprint, 1982, # 10, p. 2863 - 2878
[2] Organic and Biomolecular Chemistry, 2011, vol. 9, # 22, p. 7836 - 7848
[3] Tetrahedron Letters, 2017, vol. 58, # 20, p. 1989 - 1991
[4] Journal of Organic Chemistry, 2017, vol. 82, # 21, p. 11585 - 11593
[5] Journal of Medicinal Chemistry, 1994, vol. 37, # 7, p. 999 - 1014
3-Acetyl-2-bromopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Acetyl-2-bromopyridine manufacturers
- Product
- 3-Acetyl-2-bromopyridine 84199-61-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-23
- Product
- 3-Acetyl-2-bromopyridine 84199-61-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-12
- Product
- 3-Acetyl-2-bromopyridine 84199-61-1
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08