Pyridazine, 3-bromo- (9CI)

ChemicalBook > CAS DataBase List > Pyridazine, 3-bromo- (9CI)

Pyridazine, 3-bromo- (9CI)

Description References

Product Name: Pyridazine, 3-bromo- (9CI)
CAS No.: 88491-61-6
Chemical Name: Pyridazine, 3-bromo- (9CI)
Synonyms: 3-bromopyridazine;3-bromo- (9CI);Pyridazine, 3-broMo-;3-Bromopyridazine ,97%;Pyridazine, 3-bromo- (9CI);3-broMopyridazine hydrobroMide;Pyridazine, 3-bromo- (9CI) ISO 9001：2015 REACH
CBNumber: CB11044310
Molecular Formula: C4H3BrN2
Formula Weight: 158.98
MOL File: 88491-61-6.mol

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Pyridazine, 3-bromo- (9CI) Property

Melting point:: 73-74 °C
Boiling point:: 270.0±13.0 °C(Predicted)
Density: 1.726±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
form: solid
pka: 0.99±0.10(Predicted)
color: Yellow to reddish brown
CAS DataBase Reference: 88491-61-6

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TRC

Product number: B695863
Product name: 3-Bromopyridazine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-W004020
Product name: 3-Bromopyridazine
Purity: 99.83%
Packaging: 1g
Price: $55
Updated: 2021/12/16

Oakwood

Product number: 078228
Product name: 3-Bromopyridazine
Packaging: 250mg
Price: $26
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB72022
Product name: 3-Bromopyridazine
Packaging: 250mg
Price: $65
Updated: 2021/12/16

Oakwood

Product number: 078228
Product name: 3-Bromopyridazine
Packaging: 1g
Price: $76
Updated: 2021/12/16

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Pyridazine, 3-bromo- (9CI) Chemical Properties,Usage,Production

Description

3-Bromopyridine can undergo lithiation with LDA at low temperatures in the 4-position: Heterocycles, involved in formation of the Grignard by Mg exchange with i-PrMgCl and in transmetallation of the lithiated derivative with zinc chloride followed by treatment with an electrophile as a route to 4-substituted 3-bromopyridines^1-4. 3-Bromopyridine is also used as an intermediate in the synthesis of Active Pharmaceutical Ingredients especially Abiraterone acetate (an antiandrogen medication which is used in the treatment of prostate cancer) and Zimelidine (selective serotonin reuptake inhibitor (SSRI) antidepressants)⁵.

References

Jennifer A. Love Dr.; John P. Morgan.;Tina M. Trnka.;Robert H. Grubbs Prof. A Practical and Highly Active Ruthenium-Based Catalyst that Effects the Cross Metathesis of Acrylonitrile. Angewandte Chemie International Edition. 2002, 41 (21), 4035-4037.
Wenjie Li.; Dorian P. Nelson.; Mark S. Jensen.; R. Scott Hoerrner.; Dongwei Cai.; Robert D. Larsen.; Paul J. Reider. An Improved Protocol for the Preparation of 3-Pyridyland Some Arylboronic Acids. J. Org. Chem. 2002, 57 (16), 5394-5397.
https://www.alfa.com/en/catalog/A12894/
Cai, Dongwei, R. D. Larsen, and P. J. Reider. "Effective lithiation of 3-bromopyridine: synthesis of 3-pyridine boronic acid and variously 3-substituted pyridines." Cheminform 33.38(2002):4285-4287.
www.jubl.com/uploads/files/48msds_msds-3-bromopyridine.pdf

Pyridazine, 3-bromo- (9CI) Preparation Products And Raw materials

Raw materials

Hydrazinium hydroxide solution Ethanol Phosphorus oxybromide Palladium Mucobromic acid

Preparation Products

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View Lastest Price from Pyridazine, 3-bromo- (9CI) manufacturers

Henan Fengda Chemical Co., Ltd

Product: 3-Bromopyridazine 88491-61-6
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-02

Shaanxi Dideu Medichem Co. Ltd

Product: Pyridazine, 3-bromo- (9CI) 88491-61-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-04-29

Shanghai Rlavie Technology Co ltd

Product: 3-bromopyridazine 88491-61-6
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 98%min
Supply Ability: 100kgs/month
Release date: 2021-11-27

88491-61-6, Pyridazine, 3-bromo- (9CI)Related Search:

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Pyridazine, 3-bromo- (9CI)

3-Bromopyridazine ,97%

Pyridazine, 3-broMo-

3-broMopyridazine hydrobroMide

3-bromopyridazine

Pyridazine, 3-bromo- (9CI) ISO 9001：2015 REACH

3-bromo- (9CI)

88491-61-6

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