Pyridazine, 3-bromo- (9CI)
Description References- Product Name
- Pyridazine, 3-bromo- (9CI)
- CAS No.
- 88491-61-6
- Chemical Name
- Pyridazine, 3-bromo- (9CI)
- Synonyms
- 3-bromopyridazine;3-bromo- (9CI);Pyridazine, 3-broMo-;3-Bromopyridazine ,97%;Pyridazine, 3-bromo- (9CI);3-broMopyridazine hydrobroMide;Pyridazine, 3-bromo- (9CI) ISO 9001:2015 REACH
- CBNumber
- CB11044310
- Molecular Formula
- C4H3BrN2
- Formula Weight
- 158.98
- MOL File
- 88491-61-6.mol
Pyridazine, 3-bromo- (9CI) Property
- Melting point:
- 73-74 °C
- Boiling point:
- 270.0±13.0 °C(Predicted)
- Density
- 1.726±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- form
- solid
- pka
- 0.99±0.10(Predicted)
- color
- Yellow to reddish brown
- CAS DataBase Reference
- 88491-61-6
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- B695863
- Product name
- 3-Bromopyridazine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-W004020
- Product name
- 3-Bromopyridazine
- Purity
- 99.83%
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 078228
- Product name
- 3-Bromopyridazine
- Packaging
- 250mg
- Price
- $26
- Updated
- 2021/12/16
- Product number
- FB72022
- Product name
- 3-Bromopyridazine
- Packaging
- 250mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 078228
- Product name
- 3-Bromopyridazine
- Packaging
- 1g
- Price
- $76
- Updated
- 2021/12/16
Pyridazine, 3-bromo- (9CI) Chemical Properties,Usage,Production
Description
3-Bromopyridine can undergo lithiation with LDA at low temperatures in the 4-position: Heterocycles, involved in formation of the Grignard by Mg exchange with i-PrMgCl and in transmetallation of the lithiated derivative with zinc chloride followed by treatment with an electrophile as a route to 4-substituted 3-bromopyridines1-4. 3-Bromopyridine is also used as an intermediate in the synthesis of Active Pharmaceutical Ingredients especially Abiraterone acetate (an antiandrogen medication which is used in the treatment of prostate cancer) and Zimelidine (selective serotonin reuptake inhibitor (SSRI) antidepressants)5.
References
- Jennifer A. Love Dr.; John P. Morgan.;Tina M. Trnka.;Robert H. Grubbs Prof. A Practical and Highly Active Ruthenium-Based Catalyst that Effects the Cross Metathesis of Acrylonitrile. Angewandte Chemie International Edition. 2002, 41 (21), 4035-4037.
- Wenjie Li.; Dorian P. Nelson.; Mark S. Jensen.; R. Scott Hoerrner.; Dongwei Cai.; Robert D. Larsen.; Paul J. Reider. An Improved Protocol for the Preparation of 3-Pyridyland Some Arylboronic Acids. J. Org. Chem. 2002, 57 (16), 5394-5397.
- https://www.alfa.com/en/catalog/A12894/
- Cai, Dongwei, R. D. Larsen, and P. J. Reider. "Effective lithiation of 3-bromopyridine: synthesis of 3-pyridine boronic acid and variously 3-substituted pyridines." Cheminform 33.38(2002):4285-4287.
- www.jubl.com/uploads/files/48msds_msds-3-bromopyridine.pdf
Pyridazine, 3-bromo- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Pyridazine, 3-bromo- (9CI) manufacturers
- Product
- 3-Bromopyridazine 88491-61-6
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-02
- Product
- 3-bromopyridazine 88491-61-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- 100kgs/month
- Release date
- 2021-11-27
- Product
- Pyridazine, 3-bromo- (9CI) 88491-61-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-11-02