5-Bromothiophene-2-carbaldehyde

Product Name: 5-Bromothiophene-2-carbaldehyde
CAS No.: 4701-17-1
Chemical Name: 5-Bromothiophene-2-carbaldehyde
Synonyms: 5-BROMO-THIOPHENE-2-CARBALDEHYDE;5-BROMOTHIOPHENE-2-CARBOXALDEHYDE;5-BROMO-2-THIOPHENECARBOXALDEHYDE;EA356;AKOS BBS-00003268;TIMTEC-BB SBB000294;5-bromothenaldehyde;5-Bromothiophene-2-c;LABOTEST-BB LT00112291;5-BROMO-2-FORMYLTHIOPHENE
CBNumber: CB7780945
Molecular Formula: C5H3BrOS
Formula Weight: 191.05
MOL File: 4701-17-1.mol

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5-Bromothiophene-2-carbaldehyde Property

Melting point:: 55°C
Boiling point:: 105-107 °C11 mm Hg(lit.)
Density: 1.607 g/mL at 25 °C(lit.)
refractive index: n20/D 1.637(lit.)
Flash point:: 210 °F
storage temp.: 2-8°C
solubility: Soluble in chloroform and methanol.
form: Liquid After Melting
color: Clear yellow to brown
Sensitive: Air Sensitive
BRN: 108404
InChIKey: GFBVUFQNHLUCPX-UHFFFAOYSA-N
LogP: 2.566 (est)
CAS DataBase Reference: 4701-17-1(CAS DataBase Reference)
NIST Chemistry Reference: 5-Bromo-2-thiophenecarboxaldehyde(4701-17-1)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 36/37/38-20/21/22
Safety Statements: 36/37/39-26-22-36
WGK Germany: 3
Hazard Note: Irritant/Air Sensitive
TSCA: N
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 152625
Product name: 5-Bromo-2-thiophenecarboxaldehyde
Purity: 95%
Packaging: 25g
Price: $201
Updated: 2025/07/31

Sigma-Aldrich

Product number: 152625
Product name: 5-Bromo-2-thiophenecarboxaldehyde
Purity: 95%
Packaging: 100g
Price: $540.4
Updated: 2025/07/31

TCI Chemical

Product number: B1135
Product name: 5-Bromothiophene-2-carboxaldehyde
Purity: >97.0%(GC)
Packaging: 5g
Price: $34
Updated: 2025/07/31

TCI Chemical

Product number: B1135
Product name: 5-Bromothiophene-2-carboxaldehyde
Purity: >97.0%(GC)
Packaging: 25g
Price: $133
Updated: 2025/07/31

TRC

Product number: B688130
Product name: 5-Bromo-2-thiophenecarboxaldehyde
Packaging: 10g
Price: $50
Updated: 2021/12/16

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5-Bromothiophene-2-carbaldehyde Chemical Properties,Usage,Production

Chemical Properties

clear yellow to brown liquid after melting

Uses

5-Bromo-2-thiophenecarboxaldehyde was used to prepare 5-[18F]fluoro-2-2-thiophene carboxaldehyde. Also is used in biological studies as anti-inflammatory and anti-tumor activity of the marine mangrove Rhizophora apiculata.

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 1422, 1950 DOI: 10.1021/ja01159a527

Synthesis

98-03-3

4701-17-1

2.1.1 Synthesis of 5-bromo-2-thiophenecarboxaldehyde Under nitrogen protection, 2-thiophenecarboxaldehyde (6.0 g, 53.5 mmol) was dissolved in anhydrous chloroform (125 mL). Subsequently, N-bromosuccinimide (10.4 g, 58.9 mmol) was slowly added and the reaction mixture was stirred for 12 h at room temperature. After completion of the reaction, the mixture was extracted with chloroform (3 × 50 mL), and the organic phases were combined and washed with deionized water (2 × 50 mL). The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography using chloroform as eluent to afford 5-bromo-2-thiophenecarboxaldehyde as a colorless oil (10.0 g, 98% yield). 1H NMR (400 MHz, CDCl3): δ 7.20 (d, 1H, J = 4.0 Hz), 7.53 (d, 1H, J = 8.0 Hz), 9.79 (s, 1H).

References

[1] Physica B: Condensed Matter, 2017, vol. 519, p. 53 - 58
[2] Tetrahedron, 2007, vol. 63, # 37, p. 9188 - 9194
[3] Tetrahedron Letters, 2005, vol. 46, # 12, p. 1989 - 1992
[4] Patent: WO2018/67786, 2018, A1. Location in patent: Page/Page column 134; 135
[5] Journal of the Chemical Society, 1958, p. 1721

5-Bromothiophene-2-carbaldehyde Preparation Products And Raw materials

Raw materials

Triphosgene N,N-Dimethylformamide 2-Bromothiophene Phosphorus oxybromide Carbon tetrachloride Chlorobenzene N-Methylformanilide

Preparation Products

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5-Bromothiophene-2-carbaldehyde Suppliers

Americas 1 Belgium 4 China 279 Europe 3 Germany 10 India 27 Japan 4 Slovakia 1 Switzerland 3 Ukraine 1 United Kingdom 15 United States 33 Global 381

Nanjing Habo Medical Technology Co., Ltd.

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View Lastest Price from 5-Bromothiophene-2-carbaldehyde manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 5-Bromothiophene-2-carbaldehyde 4701-17-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Bromothiophene-2-carbaldehyde 4701-17-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 5-Bromothiophene-2-carbaldehyde 4701-17-1
Price: US $1.00/KG
Min. Order: 1G
Purity: 99%
Supply Ability: 100KG
Release date: 2018-08-12

4701-17-1, 5-Bromothiophene-2-carbaldehydeRelated Search:

Cephalothin sodium 2-Thiophenecarboxaldehyde Thifensulfuron methyl Tetrahydrothiophene 5-Bromothiazole Ethyl 5-bromothiophene-2-carboxylate 5-Bromothiophenesulfonyl chloride 5-Bromothiophene-2-sulfonamide METHYL4,5-DIBROMOTHIOPHENE-2-CARBOXYLATE 2-Thiophenecarboxylic acid, 4-amino-5-bromo- 2-Acetyl-5-bromothiophene 2-BROMO-1-(5-BROMOTHIOPHEN-2-YL)ETHANONE 4,5-DIBROMOTHIOPHENE-2-CARBOXALDEHYDE 5-Bromothiophene-2-carbohydrazide 5-Bromo-2-thiophenecarboxylic acid 4,5-DIBROMOTHIOPHENE-2-CARBOXYLIC ACID METHYL 4,5-DIBROMO-3-HYDROXYTHIOPHENE-2-CARBOXYLATE Bromine

2-Thiophenecarboxaldehyde, 5-bromo-

LABOTEST-BB LT00112291

5-BROMO-2-THIOPHENECARBALDEHYDE

5-BROMO-2-THIOPHENECARBOXALDEHYDE

5-BROMO-2-FORMYLTHIOPHENE

5-BROMOTHIOPHENE-2-ALDEHYDE

5-BROMO-THIOPHENE-2-CARBALDEHYDE

5-BROMOTHIOPHENE-2-CARBOXALDEHYDE

AKOS BBS-00003268

TIMTEC-BB SBB000294

5-BROMOTHIOPHENE-2-CARBALDEHYDE 98%

2-BROMO-5-THIOPHENECARBOXALDEHYDE

5-Bromothiophene-2-Aldehyde98%

5-Bromothiophene-2-Aldehyde 98%

2-BROMOTHIOPHENE-5-CARBOXALDEHYDE

5-bromothenaldehyde

5-BROMO-2-THIIOPHENE CARBOXALDEHYDE

5-Bromo-2-thiophenecarboxaL

5-bromothiophere-2-carbaldehyde

5-Bromo-2-thiophenecarboxaldehyde,97%

5-Bromo-2-thienylaldehyde

5-Bromothiophene-2-c

5-BroMo-2-thiophenecarboxaldehyde, 97% 25ML

2-BroMo-5-forMylthiophene

5-Bromo-2-formylthiophene, 5-Bromo-2-thenaldehyde

5-BroMothiophene-2-carboxaldehyde,5-BroMo-2-forMylthiophene

5-BroMo-2-thiophenecarboxaldehyde (>90%)

5-BroMo-2-thiophenecarboxaldehyde 95%

5-BroMo-2-thiophenecarboxaldehyde, 98%+

5-Bromothiophene-2-carboxaldehyde,97%

JR-8910, 5-Bromo-2-thiophenecarboxaldehyde, 95%

5-Bromothiophene-2-carboxaldehyde &gt

5-Bromothiophene-2-carbaldehyde ISO 9001：2015 REACH

EA356

5-Bromothiophene-2-carbaldehyde,4701-17-1

5-bromothiophene 2-formaldehyde

5-bromo-2-thiophencarboxaldehyde

4701-17-1

4710-17-1

C5H3O2BrS

ALDEHYDE

Heterocyclic Building Blocks

Halogenated Heterocycles

Thiophenes

Building Blocks

Heterocycle-oher series

alkyl bromide

Thiophenes & Benzothiophenes

Azoles

blocks

Bromides

Heterocycles

Aldehydes

Thiophenes & Benzothiophenes

bc0001