Ethyl 5-bromothiophene-2-carboxylate

Product Name: Ethyl 5-bromothiophene-2-carboxylate
CAS No.: 5751-83-7
Chemical Name: Ethyl 5-bromothiophene-2-carboxylate
Synonyms: 5-bromo-2-thiophenecarboxyL;5- broMothiophene -2-ethyl forMate;Ethyl 5-bromothiophen-2-carboxylate;Ethyl 5-bromothiophene-2-carboxylate;Ethyl 5-bromo-2-thiophenecarboxylate;Ethyl5-Bromothiophene-2-carboxylate>Ethyl5-bromothiophene-2-carboxylate,99%;Ethyl 5-bromothiophene-2-carboxylate ,98.5%;5-Bromothiophene-2-carboxylic acid ethyl ester;2-Thiophenecarboxylic acid, 5-broMo-, ethyl ester
CBNumber: CB8947189
Molecular Formula: C7H7BrO2S
Formula Weight: 235.1
MOL File: 5751-83-7.mol

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Ethyl 5-bromothiophene-2-carboxylate Property

Boiling point:: 94-96°C/4mm
Density: 1.572±0.06 g/cm3(Predicted)
refractive index: 1.5600 to 1.5640
Flash point:: 94-96°C/4mm
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: clear liquid
color: Light orange to Yellow to Green
Water Solubility: Slightly soluble in water
λmax: 277nm(Hexane)(lit.)
InChI: InChI=1S/C7H7BrO2S/c1-2-10-7(9)5-3-4-6(8)11-5/h3-4H,2H2,1H3
InChIKey: PZNHMXAOMDQLLE-UHFFFAOYSA-N
SMILES: C1(C(OCC)=O)SC(Br)=CC=1

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Safety

HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: E1111
Product name: Ethyl 5-Bromothiophene-2-carboxylate
Purity: >98.0%(GC)
Packaging: 1g
Price: $26
Updated: 2025/07/31

TCI Chemical

Product number: E1111
Product name: Ethyl 5-Bromothiophene-2-carboxylate
Purity: >98.0%(GC)
Packaging: 5g
Price: $74
Updated: 2025/07/31

Usbiological

Product number: 449419
Product name: Ethyl 5-bromothiophene-2-carboxylate
Packaging: 100mg
Price: $305
Updated: 2021/12/16

TRC

Product number: E900815
Product name: Ethyl 5-Bromothiophene-2-carboxylate
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Chem-Impex

Product number: 44996
Product name: Ethyl5-Bromothiophene-2-carboxylate,≥98%(GC)
Purity: ≥98%(GC)
Packaging: 1G
Price: $26.92
Updated: 2021/12/16

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Ethyl 5-bromothiophene-2-carboxylate Chemical Properties,Usage,Production

Chemical Properties

Colourless to light yellow liquid

Uses

Ethyl 5-bromothiophene-2-carboxylate is used as an intermediate in organic syntheses

Synthesis

7311-63-9

75-03-6

5751-83-7

GENERAL STEPS: To a solution of commercially available 5-bromothiophene-2-carboxylic acid (10 g, 0.048 mol) and cesium carbonate (31.6 g, 0.096 mol) in N,N-dimethylformamide (100 mL) was slowly added ethyl iodide (11.3 g, 0.072 mol). The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the reaction was quenched with water and extracted with ethyl acetate. The organic layer was washed with saturated saline, dried over anhydrous sodium sulfate, filtered and concentrated to give the crude product. The crude product was purified by silica gel column chromatography to afford pure ethyl 5-bromothiophene-2-carboxylate (9 g, 80% yield) as a light yellow oil.ESI-MS m/z: 234.1 [M + H]+ (calculated value: C7H7BrO2S).1H NMR (CDCl3, 400 MHz): δ 7.54-7.53 (d, J = 4 Hz, 1H, Harom), 7.07-7.53 (d, J = 4 Hz, 1H, Harom). Harom), 7.07-7.06 (d, J = 4 Hz, 1H, Harom), 4.35-4.30 (m, 2H, O-CH2-CH3), 1.38-1.34 (m, 3H, O-CH2-CH3).

References

[1] European Journal of Medicinal Chemistry, 2018, vol. 150, p. 506 - 524

Ethyl 5-bromothiophene-2-carboxylate Preparation Products And Raw materials

Raw materials

2,5-Dibromothiophene Nitrogen Ethanol Tetrahydrofuran Thionyl chloride n-Butyllithium

Preparation Products

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View Lastest Price from Ethyl 5-bromothiophene-2-carboxylate manufacturers

Career Henan Chemical Co

Product: Ethyl 5-bromothiophene-2-carboxylate 5751-83-7
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-10

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Ethyl 5-bromo-2-thiophenecarboxylate

Ethyl 5-bromothiophene-2-carboxylate ,98.5%

5-Bromothiophene-2-carboxylic acid ethyl ester

Ethyl 5-bromothiophene-2-carboxylate

Ethyl 5-broMothiophene-2-carboxylateEthyl 5-broMothiophene-2-carboxylate

2-Thiophenecarboxylic acid, 5-broMo-, ethyl ester

5- broMothiophene -2-ethyl forMate

Ethyl5-bromothiophene-2-carboxylate,99%

5-bromo-2-thiophenecarboxyL

Ethyl5-Bromothiophene-2-carboxylate&gt

Ethyl 5-bromothiophene-2-carboxylate ISO 9001：2015 REACH

2-Thiophenecarboxylic acid, 5-bromo-, ethyl ester (6CI, 7CI, 8CI, 9CI, ACI)

5-bromo-2-Thiophenecarboxylic acid ethyl ester (6CI 7CI 8CI 9CI ACI)

Ethyl 5-bromothiophen-2-carboxylate

5751-83-7