2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)-

Product Name: 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)-
CAS No.: 452339-73-0
Chemical Name: 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)-
Synonyms: (5R)-5-(2,2-DiMethyl-4H-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-one;(R)-5-(2,2-DIMETHYL-4H-BENZO[D][1,3]DIOXIN-6-YL)OXAZOLIDIN-2-ONE;BNKY020-VT04;Vilanterol internate 1;Vilanterol Impurity 29;Vilanterol Impurity 74;(5R)-2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl);(5R)-2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-y...;(R)-5-(2,2-Dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxazolidinone;(R)-5-(2,2-Dimethyl-4H-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-one
CBNumber: CB12563399
Molecular Formula: C13H15NO4
Formula Weight: 249.26
MOL File: 452339-73-0.mol

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2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)- Property

Melting point:: 160 - 163°C
Boiling point:: 489.6±45.0 °C(Predicted)
Density: 1.223±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Chloroform (Sparingly), Methanol (Slightly)
pka: 12.29±0.40(Predicted)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D456836
Product name: (R)-5-(2,2-Dimethyl-4H-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-one
Packaging: 100mg
Price: $275
Updated: 2021/12/16

AK Scientific

Product number: 1968CS
Product name: (5R)-5-(2,2-Dimethyl-4H-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-one
Packaging: 100mg
Price: $101
Updated: 2021/12/16

AK Scientific

Product number: 1968CS
Product name: (5R)-5-(2,2-Dimethyl-4H-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-one
Packaging: 250mg
Price: $127
Updated: 2021/12/16

aablocks

Product number: AA00DAZ6
Product name: (5R)-5-(2,2-Dimethyl-4h-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-one
Purity: 97%
Packaging: 1g
Price: $176
Updated: 2021/12/16

Crysdot

Product number: CD11121927
Product name: (R)-5-(2,2-Dimethyl-4H-benzo[d][1,3]dioxin-6-yl)oxazolidin-2-one
Purity: 97%
Packaging: 250mg
Price: $218
Updated: 2021/12/16

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2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)- Chemical Properties,Usage,Production

Uses

(5R)-5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-Oxazolidinone (2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)-) is a reagent applied in the preparation of alkyl-linked di-phenyl aminoalcohols as long-acting β2 adrenergic receptor agonist. It is used as an antedrug.

Synthesis

(R)-2-amino-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethan-1-ol (29.8g, 134.0mmol, 1.0eq.) and tetrahydrofuran (300mL) were added to the reaction flask under nitrogen protection, the reaction solution was heated to 40-60°C, and N, N'- Carbonyldiimidazole (22.7 g, 140.0 mmol, 1.05 eq.).After the addition, the reaction solution was kept at a temperature of 40-60° C. and stirred until the raw material reaction was completed. After the reaction, the solution was cooled to 15-30° C., and water (400 mL) was added. Then, the mixture was continuously cooled to 0-10°C and kept stirring. The precipitated solid was filtered, and the filter cake was washed with water. The filter cake was collected and dried under reduced pressure to obtain 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)- (30 g, 120.4 mmol, 89.9% yield).

2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)- Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)- Suppliers

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View Lastest Price from 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)- manufacturers

PNP Biotech Co. Ltd

Product: 2-Oxazolidinone, 5-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-,5R- 452339-73-0
Price: US $0.00/kg
Min. Order: 25kg
Purity: ≥99%
Supply Ability: Inquiry
Release date: 2022-10-28

Xiamen Wonderful Bio Technology Co., Ltd.

Product: 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)- 452339-73-0
Price: US $66.00/KG
Min. Order: 1250KG
Purity: 99.8%
Supply Ability: 2T
Release date: 2023-07-21

Hebei Yanxi Chemical Co., Ltd.

Product: (5R)-5-(2,2-Dimethyl-4H-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-on e 452339-73-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 100tons
Release date: 2023-09-12

452339-73-0, 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)-Related Search:

Ethanone, 2-bromo-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)- Ethanol, 2-[(2,6-dichlorophenyl)Methoxy]- Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro 21ξ-morpholino-23,24-dinor-chola-4,20-dien-3-one Androstenone hydrazone 17-Iodoandrosta-5,16-dien-3beta-ol BISNORCHOLENALDEHYDE tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate CarbaMic acid, [(2R)-2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]-, 1,1-diMethylethyl ester N-(1-Cyclohexen-1-yl)morpholine Abiraterone

2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)-

(5R)-2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)

(5R)-5-(2,2-DiMethyl-4H-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-one

(R)-5-(2,2-Dimethyl-4H-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-one

(R)-5-(2,2-DIMETHYL-4H-BENZO[D][1,3]DIOXIN-6-YL)OXAZOLIDIN-2-ONE

BNKY020-VT04

Vilanterol Impurity 29

Vilanterol internate 1

(5R)-2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-y...

TIANFU CHEM 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)-

(R)-5-(2,2-demethyl-4H-benzo[d] [1,3] dioxin -6-yl)oxazolidin-2-one

Vilanterol Impurity 74

(5R) -5- (2,2-dimethyl-4H-1,3-benzodioxane-6-yl) -1,3-oxazolidine-2-one

(R)-5-(2,2-Dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxazolidinone

452339-73-0

Intermediate

452339-73-0