tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate

Product Name: tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate
CAS No.: 452339-71-8
Chemical Name: tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate
Synonyms: BNKY020-VT02;Vilanterol Impurity 37;Vilanterol Impurity 30;tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl;tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoeth...;tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamate;Tert-butyl 2- (2,2-dimethyl-4H-1,3-benzodoxin-6-yl) -2-oxoethylcarbamate;tert-Butyl N-(2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl)carbamate;N-(2-(2,2-Dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl) tert-butyl carbamate;tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate
CBNumber: CB32716160
Molecular Formula: C17H23NO5
Formula Weight: 321.37
MOL File: 452339-71-8.mol

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tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate Property

Boiling point:: 489.1±45.0 °C(Predicted)
Density: 1.134±0.06 g/cm3(Predicted)
pka: 10.92±0.46(Predicted)
InChI: InChI=1S/C17H23NO5/c1-16(2,3)23-15(20)18-9-13(19)11-6-7-14-12(8-11)10-21-17(4,5)22-14/h6-8H,9-10H2,1-5H3,(H,18,20)
InChIKey: YIIVONGCNAQATO-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)NCC(C1=CC=C2OC(C)(C)OCC2=C1)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate Chemical Properties,Usage,Production

Uses

Tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate is a Vilanterol impurity. Vilanterol is a novel and selective agonist of β2-ar.

Synthesis

Trifluoroacetic acid (10.2 mL) was added to di-(tert-butyl)2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl) -2-oxoethyliminodicarbonic acid at 20°C (46.37 g) in a stirred solution of dichloromethane (500 mL) and stirred for 4 hours. Aqueous sodium hydroxide solution (0.5 M, 400 mL) was added to the reaction solution, stirred for half an hour, and separated. The organic layer was washed with water (500 mL), dried, concentrated, and recrystallized from ether to obtain tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate 15.15g, yield 43 %.

tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate Suppliers

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View Lastest Price from tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamate 452339-71-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 100tons
Release date: 2023-09-13

Anhui Yiao New Material Technology Co., Ltd

Product: tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl 452339-71-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1 ton
Release date: 2023-11-02

Anhui Yiao New Material Technology Co., Ltd

Product: tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl 452339-71-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1 ton
Release date: 2023-11-02

452339-71-8, tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamateRelated Search:

(R)-2-Amino-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanol A-1-(AMINOMETHYL)-4-HYDROXY-1,3-BENZENDIMETHANOL Ethanone, 2-bromo-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)- Ethanol, 2-[(2,6-dichlorophenyl)Methoxy]- Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro 21ξ-morpholino-23,24-dinor-chola-4,20-dien-3-one Androstenone hydrazone 17-Iodoandrosta-5,16-dien-3beta-ol BISNORCHOLENALDEHYDE CarbaMic acid, [(2R)-2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]-, 1,1-diMethylethyl ester 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)- N-(1-Cyclohexen-1-yl)morpholine Vilanterol Impurity 45 Vilanterol Impurity 25 di-(tert-butyl)2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyliMinodicarbonate Vilanterol Impurity 10 Vilanterol Impurity 14 Vilanterol Impurity 11

CarbaMic acid, [2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-diMethylethyl ester

tert-Butyl N-(2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl)carbamate

tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamate

tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl

tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate

BNKY020-VT02

Carbamic acid, [2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-dimethylethyl ester (9CI)

Vilanterol Impurity 37

Carbamic acid, N-[2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-dimethylethyl ester

tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoeth...

tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamateQ: What is tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamate Q: What is the CAS Number of tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamate

Tert - butyl 2-(2,2- dimethyl -4H-1,3- benzodioxin -6- yl )-2- Oxoethylcarb - N -amate

Tert-butyl 2- (2,2-dimethyl-4H-1,3-benzodoxin-6-yl) -2-oxoethylcarbamate

Vilanterol Impurity 30

N-(2-(2,2-Dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl) tert-butyl carbamate

452339-71-8

Intermediate