Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
- Product Name
- Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
- CAS No.
- 503070-57-3
- Chemical Name
- Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
- Synonyms
- BNKY020-VT06;CAS 503070-57-3;ethoxymethyl]Bromohexyloxy)Vilanterol Impurity 28;Vilanterol Impurity 80;Vilanterol intermediate;BROMOHEXYL-OXY- ETHOXYMETHYLCHLOROBENZENE;2-((2-((6-bromohexyl)oxy)methyl)-1,3-dichlorobenzene;2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro
- CBNumber
- CB62563268
- Molecular Formula
- C15H21BrCl2O2
- Formula Weight
- 384.14
- MOL File
- 503070-57-3.mol
Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Property
- Boiling point:
- 420.8±45.0 °C(Predicted)
- Density
- 1.335±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- color
- Colourless
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B683630
- Product name
- 2-[2-(6-Bromohexyloxy)ethoxymethyl]-1,3-dichlorobenzene
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B683630
- Product name
- 2-[2-(6-Bromohexyloxy)ethoxymethyl]-1,3-dichlorobenzene
- Packaging
- 10g
- Price
- $155
- Updated
- 2021/12/16
- Product number
- B683630
- Product name
- 2-[2-(6-Bromohexyloxy)ethoxymethyl]-1,3-dichlorobenzene
- Packaging
- 25g
- Price
- $370
- Updated
- 2021/12/16
- Product number
- B683630
- Product name
- 2-[2-(6-Bromohexyloxy)ethoxymethyl]-1,3-dichlorobenzene
- Packaging
- 5g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 1435DT
- Product name
- 2-((2-((6-Bromohexyl)oxy)ethoxy)methyl)-1,3-dichlorobenzene
- Packaging
- 5g
- Price
- $126
- Updated
- 2021/12/16
Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Chemical Properties,Usage,Production
Uses
2-[2-(6-Bromohexyloxy)ethoxymethyl]-1,3-dichlorobenzene is an intermediate in the synthesis of Vilanterol Trifenatate-d4 (V260002). Vilanterol Trifenatate (V260000) is a long-acting β2 adrenergic receptor Agonist. It demonstrates prolonged bronchodilation in subjects with asthma and COPD.
Synthesis
100mL single-necked flask, under a nitrogen atmosphere, 2-((2,6-dichlorobenzyl)oxy)ethan-1-ol (3 g, 13.5 mmol) was dissolved in 1,6-dibromo hexane (9.7 g, 40.5 mmol) tetrabutylammonium bromide (432 mg, 1.35mmol) and 50% sodium hydroxide solution (2.5g, 62.1 mmol) was added and reacted at room temperature for 16 hours. Dichloromethane (50 mL), washed successively with water (50 mL) and saturated brine (50 mL), dried over the organic phase, filtered, concentrated and purified on a silica gel column (ethyl acetate/petroleum ether = 1/12) to give a pale yellow oil Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro.
Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Preparation Products And Raw materials
Raw materials
Preparation Products
Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro Suppliers
View Lastest Price from Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro manufacturers
- Product
- Benzene, 2-[[2-[(6-bromohexyl)oxy]ethoxy]methyl]-1,3-dichloro 503070-57-3
- Price
- US $1000.00/KG
- Min. Order
- 0.1KG
- Purity
- 98%
- Supply Ability
- 500kg per month
- Release date
- 2020-06-10
- Product
- Benzene, 2-[[2-[(6-bromohexyl)oxy]ethoxy]methyl]-1,3-dichloro 503070-57-3
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- ≥98%
- Supply Ability
- Inquiry
- Release date
- 2022-10-28
- Product
- Benzene, 2-[[2-[(6-bromohexyl)oxy]ethoxy]methyl]-1,3-dichloro- 503070-57-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 100tons
- Release date
- 2023-09-15