Sofosbuvir IMpurity C

ChemicalBook > CAS DataBase List > Sofosbuvir IMpurity C

Product Name: Sofosbuvir IMpurity C
CAS No.: 1337482-15-1
Chemical Name: Sofosbuvir IMpurity C
Synonyms: Ofosbuvi rimpurity;Sofosbuvir impurity G;sofosbuvir impurity Y008005-G;Sofosbuvir IMpurity C 1337482-15-1;Sofosbuvir impurity G,inhibit,Inhibitor;Sofosbuvir 5'-Desphosphate 3’-O-[(S)-Phosphate];L-Alanine, N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-3'-uridylyl]-, 1-methylethyl ester;((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosph;isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosph;isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alanite
CBNumber: CB32716544
Molecular Formula: C22H29FN3O9P
Formula Weight: 529.45
MOL File: 1337482-15-1.mol

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Sofosbuvir IMpurity C Property

Density: 1.41±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: soluble in No data available
pka: 9.39±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: S675610
Product name: Sofosbuvir5''-Desphosphate3''-O-[(S)-Phosphate]
Packaging: 5mg
Price: $195
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 67031
Product name: Sofosbuvir5??-Desphosphate3??-O-[(S)-Phosphate]
Packaging: 50mg
Price: $2400
Updated: 2021/12/16

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Sofosbuvir IMpurity C Chemical Properties,Usage,Production

Uses

Sofosbuvir 5''-Desphosphate 3''-O-[(S)-Phosphate] is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

Sofosbuvir IMpurity C Preparation Products And Raw materials

Raw materials

Preparation Products

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1337482-15-1, Sofosbuvir IMpurity CRelated Search:

SofosBuvir Impurity 53 Zolmitriptan ((2R,3R,4R,5R)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-4-Methyltetrahydrofuran-2-yl)Methyl benzoate Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI) PSI-7977-13C-d3 SofosBuvir Impurity 40 2'-deoxy-2'-fluoro-2'-C-methyluridine SofosBuvir Impurity 54 D-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-Methyl-P-phenyl-5'-uridylyl]-, 1-Methylethyl ester Sofosbuvir metabolites GS566500 sofosBuvir impurity 41 Sofosbuvir Impurity 7 Sofosbuvir Impurity25 Sofosbuvir impurity L Sofosbuvir Impurity Q sofosBuvir Impurity 35 Sodium stearyl lactate Sofosbuvir

Sofosbuvir IMpurity C 1337482-15-1

Ofosbuvi rimpurity

isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alaninate

Sofosbuvir impurity G

(2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate

isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alanite

Sofosbuvir 5'-Desphosphate 3’-O-[(S)-Phosphate]

sofosbuvir impurity Y008005-G

Sofosbuvir impurity 18/Sofosbuvir 3'-O-Phosphoramidate/Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alaninate

L-Alanine, N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-3'-uridylyl]-, 1-methylethyl ester

isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosph

Sofosbuvir impurity G,inhibit,Inhibitor

((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosph

1337482-15-1

1496552-51-1