ChemicalBook > CAS DataBase List > AP-761

AP-761

Product Name
AP-761
CAS No.
1093108-50-9
Chemical Name
AP-761
Synonyms
AP-761;BI671800;BI-67180;BI-671800 ，S0495;AP-761 / BI671800;BI-671800 (Actimis);BI 671800 (BI671800);BI-671800, 10 mM in DMSO;BI671800;AP-761;AP761;AP 761;BI-671800,BI671800,Inhibitor,BI 671800,Prostaglandin Receptor,inhibit
CBNumber
CB32728622
Molecular Formula
C25H26F3N5O3
Formula Weight
501.5
MOL File
1093108-50-9.mol
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AP-761 Property

Boiling point:
611.4±55.0 °C(Predicted)
Density 
1.351±0.06 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
DMSO: soluble
form 
A crystalline solid
pka
3.20±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27638
Product name
BI-671800
Packaging
5mg
Price
$692
Updated
2024/03/01
Cayman Chemical
Product number
27638
Product name
BI-671800
Packaging
10mg
Price
$1169
Updated
2024/03/01
Cayman Chemical
Product number
27638
Product name
BI-671800
Packaging
1mg
Price
$214
Updated
2024/03/01
TRC
Product number
B591753
Product name
BI-671800
Packaging
2.5mg
Price
$565
Updated
2021/12/16
ChemScene
Product number
CS-0070031
Product name
BI-671800
Purity
99.06%
Packaging
100mg
Price
$2650
Updated
2021/12/16
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AP-761 Chemical Properties,Usage,Production

Uses

BI-671800 is a selective and potent CRTH2 antagonist.

in vivo

BI-671800 (compound A, 0.1-10 mg/kg, i.g.) shows significant inhibition of AHR in mice[1].
BI-671800 (compound A), effectively blocks edema formation and greatly reduces the inflammatory infiltrate and skin pathology observed in drug vehicle-treated animals[3].

Animal Model:6-8-week-old age- and sex-matched BALB/c mice (mice were sensitized for 14 days, challenged intranasally)[1].
Dosage:10-0.1 mg/kg
Administration:Oral gavage for 4 weeks
Result:Shows significant inhibition of AHR in mice.

IC 50

hCRTH2: 4.5 nM (IC50); mCRTH2: 3.7 μM (IC50)

AP-761 Preparation Products And Raw materials

Raw materials

Preparation Products

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AP-761 Suppliers

China 44 United States 7 Global 51
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Taizhou Tongxin Bio-Tech Co., Ltd
Tel
0523-86818997 18652728585
Email
sales@allyrise.com
Country
China
ProdList
2966
Advantage
60
Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
Country
China
ProdList
984
Advantage
55
Taizhou Ruixin Chemical Co., Ltd.
Tel
0576-89085261 15867635987
Fax
0576-89085262
Email
jasonhu09@163.com
Country
China
ProdList
442
Advantage
50
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Shanghai jing Hao pharmaceutical technology co., LTD
Tel
021-68900963 15618693615
Fax
021-68900963
Email
sales@jinghaopharma.com
Country
China
ProdList
300
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
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View Lastest Price from AP-761 manufacturers

Career Henan Chemical Co
Product
AP-761 1093108-50-9
Price
US $2.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
ask
Release date
2020-01-08

1093108-50-9, AP-761Related Search:

2,6-Difluorobenzonitrile p-Toluic acid Methacryloyl chloride 2,6-Difluorobenzamide

  • AP-761
  • 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]-
  • BI671800
  • BI671800;AP-761;AP761;AP 761
  • BI 671800 (BI671800)
  • AP-761 / BI671800
  • BI-67180
  • BI-671800,BI671800,Inhibitor,BI 671800,Prostaglandin Receptor,inhibit
  • BI-671800 (Actimis)
  • 2-(4,6-Bis(dimethylamino)-2-(4-(4-(trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl)acetic acid
  • BI-671800, 10 mM in DMSO
  • BI-671800 ，S0495
  • 1093108-50-9
  • AP-761