ChemicalBook > CAS DataBase List > 1,4-Phenylenebisboronic acid

1,4-Phenylenebisboronic acid

Product Name: 1,4-Phenylenebisboronic acid
CAS No.: 4612-26-4
Chemical Name: 1,4-Phenylenebisboronic acid
Synonyms: 1,4-PHENYLENEDIBORONIC ACID;BENZENE-1,4-DIBORONIC ACID;1,4-BENZENEDIBORONIC ACID;1,4-Phenyldiboronic acid;1,4-PHENYLENEBIS(BORONIC ACID);p-Benzenediboronic acid;(4-Boronophenyl)boronic acid;NSC 25410;AKOS BRN-0002;enebisboronic acid
CBNumber: CB3274806
Molecular Formula: C6H8B2O4
Formula Weight: 165.75
MOL File: 4612-26-4.mol

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1,4-Phenylenebisboronic acid Property

Melting point:: >350 °C(lit.)
Boiling point:: 420.1±55.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
pka: 8.30±0.17(Predicted)
form: liquid
color: white to off-white
Water Solubility: Soluble in water 2.5%.
BRN: 2836921
InChI: InChI=1S/C6H8B2O4/c9-7(10)5-1-2-6(4-3-5)8(11)12/h1-4,9-12H
InChIKey: BODYVHJTUHHINQ-UHFFFAOYSA-N
SMILES: C1(B(O)O)=CC=C(B(O)O)C=C1
CAS DataBase Reference: 4612-26-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,C,Xi
Risk Statements: 22-36/37/38-20/21/22
Safety Statements: 36-26
WGK Germany: 3
Hazard Note: Corrosive
TSCA: No
HazardClass: IRRITANT
HS Code: 29310095

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 417130
Product name: Benzene-1,4-diboronic acid
Purity: ≥95.0%
Packaging: 5g
Price: $126
Updated: 2025/07/31

Sigma-Aldrich

Product number: 417130
Product name: Benzene-1,4-diboronic acid
Purity: ≥95.0%
Packaging: 25g
Price: $301
Updated: 2025/07/31

TCI Chemical

Product number: P1358
Product name: 1,4-Phenylenediboronic Acid (contains varying amounts of Anhydride)
Packaging: 1g
Price: $32
Updated: 2025/07/31

TCI Chemical

Product number: P1358
Product name: 1,4-Phenylenediboronic Acid (contains varying amounts of Anhydride)
Packaging: 5g
Price: $83
Updated: 2025/07/31

TCI Chemical

Product number: P1358
Product name: 1,4-Phenylenediboronic Acid (contains varying amounts of Anhydride)
Packaging: 25g
Price: $246
Updated: 2025/07/31

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1,4-Phenylenebisboronic acid Chemical Properties,Usage,Production

Chemical Properties

1,4-Phenylenebisboronic acid is off-white powder

Uses

Reagent used for . Externally initiated Kumada catalyst-transfer polycondensation . Suzuki-Miyaura cross-coupling reactions . Energy transfer processes in optoelectronic devices . Palladium-catalyzed sequential alkenylation and conjugate addition reactions . Scholl cyclizations

Uses

suzuki reaction

Uses

It is used for palladium-catalyzed sequential alkenylation and conjugate addition reactions, scholl cyclizations, Suzuki-Miyaura cross-coupling reactions. It is also used in the preparation of indolizine derivatives as OLEDs, in organic thin-film transistors, Fluorescence and solution-processable coordination polymers.

Synthesis

121-43-7

106-37-6

4612-26-4

Under the protection of nitrogen atmosphere, 200 mL of tetrahydrofuran (THF) was added to the reaction flask and cooled to 15°C. 0 g (0.62 mmol) of magnesium and 1.0 g (0.004 mol) of iodine were slowly added followed by the dropwise addition of 300 mL of THF solution containing 68.4 g (0.29 mol) of 1,4-dibromobenzene at a controlled titration rate maintaining the reaction temperature at 30°C. The reaction was continued for 3 hours. After completion, the reaction was continued for 3 hours. After completion of the reaction, the reaction mixture was cooled to -70°C and a mixed solution consisting of trimethyl borate (78.5 mL, 0.72 mol) and 300 mL of THF was slowly added dropwise. After the dropwise addition was completed, the reaction was continued at -70°C for 1 hour, then slowly warmed to room temperature and stirred for 12 hours. To the reaction mixture was added 950 mL of 2.5 M hydrochloric acid, stirred rapidly for 15 minutes and the solid product was collected by filtration. The solid was washed 3 times with 300 mL of hexane and finally dried under vacuum to give 40.7 g of white solid 1,4-phenylenediboronic acid in 84.6% yield.

References

[1] Patent: CN103570530, 2016, B. Location in patent: Paragraph 0042; 0043

1,4-Phenylenebisboronic acid Preparation Products And Raw materials

Raw materials

Trimethyl borate Tetrahydrofuran Diethyl ether 1,4-Dibromobenzene Magnesium Sulfuric acid

Preparation Products

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1,4-Phenylenebisboronic acid Suppliers

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View Lastest Price from 1,4-Phenylenebisboronic acid manufacturers

PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD

Product: 1,4-Phenylenebisboronic acid 4612-26-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2 MTs
Release date: 2024-08-06

Shanghai UCHEM Inc.

Product: Benzene-1,4-diboronic acid 4612-26-4
Price: US $27.00-191.00/g
Min. Order: 25g
Purity: 0.98
Supply Ability: 100kg
Release date: 2023-11-23

Henan Fengda Chemical Co., Ltd

Product: 1,4-Phenylenebisboronic acid 4612-26-4
Price: US $8.00-3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-03

4612-26-4, 1,4-Phenylenebisboronic acidRelated Search:

P-DIVINYLBENZENE 85 Terephthalic acid Bis(2-ethylhexyl) phthalate Zinc borate Tetrachloroterephthalonitrile 4-Aminophenylboronic acid p-Phenylenediamine Phenylboronic acid TEREPHTHALIC DIHYDRAZIDE Terephthalaldehyde Boric acid Benzophenone Benzene 1,4-Benzenediboronic acid bis(pinacol) ester 1,4-BENZENEDIBORONIC ACID BIS(NEOPENTYL GLYCOL) ESTER 1,3-Benzenediboronic acid 1,4-Phenylenebisboronic acid 2,5-Bis(methoxymethyl)-1,4-phenylenediboronic acid

BENZENE-1,4-DIBORONIC ACID

1,4-BENZENEDIBORONIC ACID

1,4-PHENYLENEDIBORONIC ACID

1,4-PHENYLENEBIS(BORONIC ACID)

4-(DIHYDROXYBORYL)PHENYLBORONIC ACID

AKOS BRN-0002

P-PHENYLENEDIBORONIC ACID

1,4-Phenyldiboronic acid

1,4-Phenylenebisboronic

1,4-benzeendiboronic acid

1,4-Benzenediboronicacid,96%

enebisboronic acid

1,4-Phenylenediboronic Acid (contains varying amounts of Anhydride)

1,4-Benzendiboronic acid

1,4-Phenylenebisboronic acid, p-Phenylenediboronic acid, Benzene-1,4-diboronic acid

Benzene-1,4-diboronic acid,98%

4-(Dihydroxyboryl)phenylboronic acid, May contain varying amounts of anhydride, 97%

Benzene-1,4-diboronic acid,1,4-Phenylenebisboronic acid, p-Phenylenediboronic acid, Benzene-1,4-diboronic acid

1,4-two benzeneboric acid

Benzene-1,4-diboronic acid >=95.0%

1, 4 - benzene boric acid

NSC 25410

p-Benzenediboronic acid

1,4-Benzenediboronic acid, 96% white to pale cream powder

Boronic acid, B,B'-1,4-phenylenebis-

(4-Boronophenyl)boronic acid

1,4-Phenylenebisboronicaci

Perampanel Impurity 30

4612-26-4

C6H4BOH22

C6H8B2O4

Aryl

Boronic Acids and Derivatives

Boronic Acids

B (Classes of Boron Compounds)

Organometallic Reagents

B (Classes of Boron Compounds)

blocks

BoronicAcids

Boronic acids