SOLASONINE

ChemicalBook > CAS DataBase List > SOLASONINE

Product Name: SOLASONINE
CAS No.: 19121-58-5
Chemical Name: SOLASONINE
Synonyms: SOLASONIN;PURAPURIN;NSC 82149;SOLANINE S;PURAPURINE;SOLASONINE;SOLANCARPIN;Solasoonine;SOLASODAMINE;α-Solasonine
CBNumber: CB3274987
Molecular Formula: C45H73NO16
Formula Weight: 884.07
MOL File: 19121-58-5.mol

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SOLASONINE Property

Melting point:: 301-303℃
alpha: D23 -88° (c = 1.01 in pyridine); D22 -74.5° (c = 0.51 in methanol)
Density: 1.42
solubility: DMSO : 100 mg/mL (113.11 mM; Need ultrasonic)
form: powder
pka: 12.78±0.70(Predicted)
color: White-beige
LogP: 4.350 (est)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

TRC

Product number: S676600
Product name: α-Solasonine
Packaging: 1mg
Price: $115
Updated: 2021/12/16

Usbiological

Product number: 300993
Product name: Solasonine
Packaging: 10mg
Price: $390
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594310
Product name: Solasonine
Packaging: 20mg
Price: $391
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb104521
Product name: Solasonine
Purity: >98%,Standard References Grade
Packaging: 20mg
Price: $569.5
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594310
Product name: Solasonine
Packaging: 100mg
Price: $799
Updated: 2021/12/16

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SOLASONINE Chemical Properties,Usage,Production

Description

This gly<:oalkaloid occurs in several species of Solanum including S. aviculare, S. sodomeum, S. verbascifolium and S. xanthocarpum. The alkaloid crystallizes from 80 per cent EtOH with 4.5 H20, m.p. 245-250°C (dec.), the anhydrous form being obtained from absolute MeOH. It has [α]²⁵_D - 68° (EtOH) and yields the following salts: hydrochloride, m.p. 265°C; picrate, m.p. 199-201 °C; picrolonate, m.p. 230-loC and the acetyl derivative, m.p. l35-8°C. On alkaline hydrolysis, the alkaloid gives solasodine and one mole each of galactose, glucose and rhamnose. The solution in concentrated H2S04 eventually gives a crimson colour with a brown fluorescence.

Uses

α-Solasonine is a natural glycoalkaloid compound which has been shown to inhibit Gli-mediated transcritional activity.

Definition

ChEBI: Solasonine is an azaspiro compound, an oxaspiro compound and a steroid.

Purification Methods

Solasonine crystallises from aqueous 80% dioxane or MeOH in needles. [Bell & Briggs J Chem Soc 1 1942, Briggs et al. J Chem Soc 4645 1961, Briggs et al. J Chem Soc 2848 1963.] The picrate crystallises from 30% aqueous EtOH with m 197-198o(dec) [Briggs & Cambie J Chem Soc 1422 1958]. [Beilstein 27 III/IV 2006.]

References

Oddo et a/., Gazzetta, 35, 27 (1905)
Levi., J. Soc. Chem. Ind., 49, 395T (1930)
Briggs., Nature, 144, 247 (1939)
Briggs.,J. Chem. Soc., 3 (1942)
Briggs, Vining., ibid, 2809 (1953)
Hayes, Scaforth., ibid, 74S (1963)

SOLASONINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from SOLASONINE manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: SOLASONINE 19121-58-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-24

Shanghai Standard Technology Co., Ltd.

Product: Solasonine 19121-58-5
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-22

NanJing Spring & Autumn Biological Engineering CO., LTD.

Product: Solasonine 19121-58-5 19121-58-5
Price: US $52.00/mg
Min. Order: 20mg
Purity: ≥98%
Supply Ability: 1000.00 kgs
Release date: 2019-07-18

19121-58-5, SOLASONINERelated Search:

Solamargine SOLASODINE Monomelittoside Gypenoside L Angoroside C (2R)-2,3-Dihydroxypropyl-b-D-galactopyranoside D-Galactose 2-(2-DODECYLOXYETHOXY)ETHANOL 2-(HEXADECYLOXY)ETHANOL SEC-BUTYL ETHER 12-AMINO-1-DODECANOL 1,1,2-TRIETHOXYETHANE Cyclopentamine CHOLESTERYL ETHYL ETHER Dipropylene glycol monomethyl ether Cholesterol Citronellol 2-(DODECYLOXY)ETHANOL

Solasonine alpha-Solasonine

NSC 82149

PURAPURIN

PURAPURINE

SOLANINE S

SOLANCARPIN

Solasonine 19121-58-5

SOLASODAMINE

SOLASONIN

SOLASONINE

5-SOLASODEN-3BETA-OL 3-O-6-D-DEOXY-ALPHA-L-MONOPYRANOSYL (1->2)-BETA-D-GLUCOPYRANOSYL (1->3)-BETA-D-GALACTOPYRANOSIDE

.beta.-D-Galactopyranoside, (3.beta.,22.alpha.,25R)-spirosol-5-en-3-yl O-6-deoxy-.alpha.-L-mannopyranosyl-(1?2)-O-.beta.-D-glucopyranosyl-(1?3)-

SOLASONINE(RG)

[(22R,25R)-Spirosol-5-en-3β-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-3-O-(β-D-glucopyranosyl)-β-D-galactopyranoside

Solasoonine

ALPHA-SOLASONINE

β-D-Galactopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-

α-Solasonine

(2S,3R,4S,5S,6R)-2-(((2R,3S,4S,5R,6R)-3-hydroxy-2-(hydroxymethyl)-6-(((2'S,4S,5'R,6aR,6bS,8aS,8bR,9S,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,4,5,6,6a,6b,7,8,8a,8b,9,11a,12,12a,12b-hexadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-yl)oxy)-5-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Solasonine extrapure, 98%

Solasonine (6CI, 7CI, 8CI)

β-D-Galactopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-

19121-58-5

C45H73NO16

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Alkaloids