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Norepinephrine Bitartrate

Product Name
Norepinephrine Bitartrate
CAS No.
69815-49-2
Chemical Name
Norepinephrine Bitartrate
Synonyms
NOREPINEPHRINE BITARTRATE;NOREPINEPHRINE BITARTRATE;Noradrenaline bitartrate;d-Bitartrate;L-NOREPINEPHRINE HYDROGEN L-TARTRATE MONOHYDRATE;Noradrenalini Bitartas;Norepinephrine Bitartate;NOREPINEPHRINE BITARTRATE;Noradrenaline Bitartrate RS;Noradrenaline bitartrate API
CBNumber
CB3275151
Molecular Formula
C12H19NO10
Formula Weight
337.28
MOL File
69815-49-2.mol
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Norepinephrine Bitartrate Property

Melting point:
102-105 °C
alpha 
-46 º (c=0.5, HCl)
storage temp. 
2-8°C
solubility 
H2O: 50 mg/mL, clear
InChI
InChI=1S/C8H11NO3.C4H6O6/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10)
InChIKey
WNPNNLQNNJQYFA-UHFFFAOYSA-N
SMILES
C1(C(O)CN)=CC=C(O)C(O)=C1.C(O)(C(=O)O)C(O)C(=O)O
CAS DataBase Reference
69815-49-2(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
26/27/28
Safety Statements 
45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
8-10-23
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris
Product number
5169
Product name
Noradrenalinebitartrate
Purity
≥99%(HPLC)
Packaging
50
Price
$65
Updated
2021/12/16
Usbiological
Product number
256014
Product name
Noradrenaline bitartrate
Packaging
50mg
Price
$290
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
18724
Product name
NoradrenalineBitartrate
Packaging
5mg
Price
$950
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
18724
Product name
NoradrenalineBitartrate
Packaging
25mg
Price
$1500
Updated
2021/12/16
AvaChem
Product number
3742H
Product name
Norepinephrine Bitartrate Monohydrate
Packaging
10mg
Price
$39
Updated
2021/12/16
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Norepinephrine Bitartrate Chemical Properties,Usage,Production

Uses

adrenergic agonist, antihypotensive

Uses

L-(ndash)-Norepinephrine-(+)-bitartrate is a α,β-adrenoceptor (AR) agonist.

Application

Norepinephrine Bitartrate for Injection is used to treat several conditions, including heart attack, low blood pressure, and shock. They help to keep the heart pumping and restore blood pressure to normal levels. Norepinephrine Bitartrate for Injection is given by injection into a vein. Norepinephrine Bitartrate for Injection is a medication used to treat low blood pressure (hypotension) and shock. It acts as a vasoconstrictor, meaning it constricts blood vessels to increase blood pressure and stimulate the heart. This helps to improve circulation and oxygen delivery to vital organs in the body. The single-dose vial contains a solution of 1 mg/mL of norepinephrine bitartrate, a salt form of norepinephrine, a naturally occurring hormone and neurotransmitter in the body. The vials are typically packaged in boxes of 10 for multiple doses. This medication is administered through intravenous (IV) injection by a healthcare professional. It is commonly used in emergency situations such as severe allergies, sepsis or during surgery to maintain stable blood pressure levels. It may also be prescribed for certain heart conditions and types of shock caused by low blood volume.

brand name

Levophed (Hospira).

Mechanism of action

Norepinephrine Bitartrate is a bitartrate salt of norepinephrine, a synthetic phenylethylamine that mimics the sympathomimetic actions of endogenous norepinephrine. Norepinephrine bitartrate acts directly on the alpha- and beta-adrenergic receptors. Clinically, norepinephrine is used as a peripheral vasoconstrictor that causes constriction of arterial and venous beds via its alpha-adrenergic action. It is also used as a potent inotropic and chronotropic stimulator of the heart mediated through its beta-1 adrenergic action.

Purification Methods

Recrystallise adrenor from EtOH and store it in the dark under N2. [pKa, Lewis Brit J Pharmacol Chemother 9 488 1954, UV: Bergstr.m et al. Acta Physiol Scand 20 101 1950, Fluorescence: Bowman et al. Science NY 122 32 1955, Tullar J Am Chem Soc 70 2067 1948.] The L-tartrate salt monohydrate has m 102-104.5o, [] D -11o (c 1.6, H2O), after recrystallisation from H2O or EtOH. [Beilstein 13 III 2382.]

Norepinephrine Bitartrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Norepinephrine Bitartrate Suppliers

Xinxiang City Oran Biotechnology Co. Ltd.
Tel
0373-6766851 18568539857
Fax
0373-6766851
Email
alchemic516@163.com
Country
China
ProdList
67
Advantage
58
Wuhan Chujiang Haoyu Chemical Technology Development Co., Ltd.
Tel
18171284407
Email
1850853183@qq.com
Country
China
ProdList
307
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58
Tianjin Famoxi Biopharmaceutical Technology Co., Ltd
Tel
18522868115; 18522868115
Email
yuqingliu@bio-pharmacn.com
Country
China
ProdList
8
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Zhejiang Boxiao Bio-Pharmaceutical Co., Ltd.
Tel
0571-63280982
Email
Helana_Huang@bx-biopharm.com
Country
China
ProdList
53
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58
HUBEI MICRO PHARMACEUTICAL
Tel
18627055345
Email
info@micropharm.cn
Country
China
ProdList
67
Advantage
58
Yunnan Huapai Pharmaceutical Technology Co., Ltd.
Tel
13135652018 18662190408
Email
275443226@qq.com
Country
China
ProdList
79
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Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
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sales@BioChemBest.com
Country
China
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6005
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Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9510
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Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
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China
ProdList
14103
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XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
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View Lastest Price from Norepinephrine Bitartrate manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
L-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol bitartrate 69815-49-2
Price
US $999.00-800.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-21
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
L-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol bitartrate 69815-49-2
Price
US $999.00-800.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-21
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Noradrenaline bitartrate 69815-49-2
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
97%-102%; USP
Supply Ability
100kg
Release date
2021-06-02

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