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L-NORADRENALINE BITARTRATE

Product Name
L-NORADRENALINE BITARTRATE
CAS No.
108341-18-0
Chemical Name
L-NORADRENALINE BITARTRATE
Synonyms
NORADRENALINE;L-ARTERENOL BITARTRATE;Epinephrine Impurity 28;L-Nradrenaline bitartrate;L-NORADRENALINE BITARTRATE;Noradrenaline tartrate CRS;L-NOREPINEPHRINE BITARTRATE;(-)-ARTERENOL BITARTRATE SALT;NOREPINEPHRINE BITARTRATE USP;L-Arterenol hydrogen L-tartrate
CBNumber
CB3417135
Molecular Formula
C12H17NO9
Formula Weight
319.27
MOL File
108341-18-0.mol
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L-NORADRENALINE BITARTRATE Property

Melting point:
100-104 °C(lit.)
refractive index 
-11 ° (C=5, H2O)
storage temp. 
Refrigerator
solubility 
H2O: soluble50mg/mL, clear
pka
8.64(at 25℃)
form 
solid
color 
white
optical activity
[α]20/D 11.5±1°, c = 2% in H2O
Water Solubility 
water: 1mg/mL
BRN 
4078502
InChI
InChI=1/C8H11NO3.C4H6O6/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10)/t8-;1-,2-/s3
InChIKey
WNPNNLQNNJQYFA-KBOIKTAVNA-N
SMILES
[C@H](C1C=CC(O)=C(O)C=1)(O)CN.[C@H](O)(C(=O)O)[C@@H](O)C(=O)O |&1:0,12,17,r|
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Safety

Hazard Codes 
T+
Risk Statements 
26/27/28-28
Safety Statements 
22-26-36/37/39-45-36/37-28
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
DN6750000
HazardClass 
6.1
PackingGroup 
III
HS Code 
2937901500
Storage Class
6.1B - Non-combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications
Acute Tox. 1 Dermal
Acute Tox. 2 Oral
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3820
Product name
Norepinephrine Bitartrate
Purity
certified reference material, pharmaceutical secondary standard
Packaging
250MG
Price
$160
Updated
2025/07/31
Sigma-Aldrich
Product number
N1100000
Product name
Noradrenaline tartrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
200 mg
Price
$164
Updated
2025/07/31
Sigma-Aldrich
Product number
1468501
Product name
Norepinephrine bitartrate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
125mg
Price
$384
Updated
2025/07/31
Sigma-Aldrich
Product number
74500
Product name
L-Norepinephrine hydrogen L-tartrate monohydrate
Purity
≥99.0% (sum of enantiomers, HPLC)
Packaging
1g
Price
$212
Updated
2023/06/20
TCI Chemical
Product number
A0906
Product name
L-Noradrenaline Bitartrate Monohydrate
Purity
>98.0%(T)
Packaging
1g
Price
$160
Updated
2025/07/31
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L-NORADRENALINE BITARTRATE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Noradrenaline bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator. Noradrenaline bitartrate monohydrate (Levophed) also directly stimulates the beta-adrenergic receptors of the heart (beta1-adrenergic receptors), but not th

Uses

A demethylated precursor of epinephrine.

Uses

Demethylated precursor of epinephrine (adrenaline). It is a sympathomimetic hormone produced by the adrenal gland.

Biochem/physiol Actions

Norepinephrine bitartrate plays an important role in in vivo and in vitro development of pathogenic and indigenous bacteria. It acts as a vasoconstrictor and adrenergic neurotransmitter.

in vivo

Norepinephrine bitartrate monohydrate can be used to induce cardiomyopathy[5][6]
Induced Cardiomyopathy Model[5][6]
Background
Norepinephrine bitartrate monohydrate is a potent growth factor for cardiomyocytes. Long-term infusion of subhyperbaric doses of Norepinephrine bitartrate monohydrate in animals can cause increases in myocardial mass and left ventricular wall thickness. Norepinephrine bitartrate monohydrate activates the Raf-1 kinase/MAP kinase cascade through α1- and β-adrenergic stimulation, and signaling pathways from both receptors synergistically induce cardiomyocyte hypertrophy.
Specific Modeling Methods
Rat: Spragues-Dawley rats adult (6 months old) male Administration: Continuously injected via an osmotic minipump 100 μg/kg/h or 200 μg/kg/h (Norepinephrine)
Modeling Indicators
Molecular changes: Left ventricular Dnmt activity ↑; ROS generation ↑; lactate dehydrogenase release ↑; dystrophin expression ↑; FHL2 protein expression ↓
Gene Expression: Expression of Dnmt1, 3a, and 3b ↑; mRNA expression of fetal genes ANP, BNP, and βMHC in left ventricle ↑
Phenotypic observation: Myocardial infarction area ↑; blood pressure continues to rise; left ventricular mass ↑; left ventricular development pressure ↓; cardiac contractility ↓. Cardiac hypertrophy.
Correlated Product(s): /
Opposite Product(s): 5-Aza-2’-deoxycytidine (HY-A0004), Prazosin (HY-B0193), Propranolol (HY-B0573B)

IC 50

α1-adrenergic receptor; α2-adrenergic receptor; Beta-1 adrenergic receptor; Microbial Metabolite; Human Endogenous Metabolite

L-NORADRENALINE BITARTRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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L-NORADRENALINE BITARTRATE Suppliers

Americas 1 Canada 1 China 188 Czech Republic 1 Europe 2 Germany 2 India 9 Japan 1 Slovakia 1 Switzerland 1 United Kingdom 3 United States 28 Global 238
Xinxiang City Oran Biotechnology Co. Ltd.
Tel
0373-6766851 18568539857
Fax
0373-6766851
Email
alchemic516@163.com
Country
China
ProdList
67
Advantage
58
Zhejiang Boxiao Bio-Pharmaceutical Co., Ltd.
Tel
0571-63280982
Email
Helena_Huang@bx-biopharm.com
Country
China
ProdList
54
Advantage
58
Shandong Shengzhiyuan Biotechnology Co., LTD
Tel
13969162569
Email
szyyy01@163.com
Country
China
ProdList
77
Advantage
58
Tianjin Famoxi Biopharmaceutical Technology Co., Ltd
Tel
18522868115; 18522868115
Email
yuqingliu@bio-pharmacn.com
Country
China
ProdList
122
Advantage
58
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
Tel
022-60189726 18812034280
Fax
86-22-60979672
Email
188120342808@163.com
Country
China
ProdList
143
Advantage
61
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44802
Advantage
61
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
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View Lastest Price from L-NORADRENALINE BITARTRATE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
L-Norepinephrine bitartrate 108341-18-0
Price
US $0.00-0.00/Kg/Bag
Min. Order
100g
Purity
97%-102%;USP
Supply Ability
100KGS
Release date
2021-07-20
Moxin Chemicals
Product
L-Noradrenaline Bitartrate Monohydrate 108341-18-0
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98%+
Supply Ability
100000
Release date
2025-02-10
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
Product
Norepinephrine Bitartrate 108341-18-0
Price
US $0.00/kg
Min. Order
1kg
Purity
98% HPLC
Supply Ability
1500 kgs
Release date
2024-05-15

108341-18-0, L-NORADRENALINE BITARTRATERelated Search:

(-)-Phenylephrine hydrogentartrate Rivastigmine tartrate Palmitoyl chloride Paclitaxel Metaraminol bitartrate Paliperidone Palmitate (-)-N-ISOPROPYL-L-NORADRENALINE HYDROCHLORIDE L-NORADRENALINE HYDROCHLORIDE Methyltransferase, noradrenaline N- N-ISOPROPYL-DL-NORADRENALINE HYDROCHLORIDE DL-NORADRENALINE,DL-NORADRENALINE 98+% (-)-NORADRENALINE,NORADRENALINE,d-(-)-noradrenalin DL-NORADRENALINE HYDROCHLORIDE noradrenaline,tartrate(1:1 N-ISOPROPYL-DL-NORADRENALINE HYDROCHLORIDE L-NORADRENALINE BITARTRATE L-ADRENALINE BITARTRATE Norepinephrine Bitartrate

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  • NORADRENALINE
  • (R)-(-)-norepinephrine L-bitartrate monohydrate,
  • (R)-(?-Norepinephrine L-bitartrate monohydrate
  • norepinephrine hydrogen tartrate monohydrate
  • L-(-)-Noradrenaline monohydrate (+)-bitartrate salt
  • L-(-)-Norepinephrine monohydrate (+)-bitartrate salt
  • L-Norepinephrine bitartrate hydride
  • L-Nradrenaline bitartrate
  • NOREPINEPHRINE BITARTRATE USP
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  • Noradrenaline bitartrate Monohydrate (Levophed)
  • Norepinephrine (bitartrate Monohydrate)
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  • Norepinephrine Bitartrate (1468501)
  • Epinephrine Impurity 28
  • Noradrenaline Tartrate Monohydrate
  • Noradrenaline Acid Tartrate / Norepinephrine Acid Tartrate
  • Norepinephrine bitartrate monohydrate,Autophagy,Levarterenol bitartrate,Norepinephrine bitartrate,Beta Receptor,L-Noradrenaline bitartrate,Inhibitor,inhibit,Adrenergic Receptor,Endogenous Metabolite
  • 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)-,(2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt), monohydrate
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  • Adrenaline Tartrate EP Impurity B as Tartrate Monohydrate
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  • Norepinephrine bitartrate monohydrate, 10 mM in DMSO
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  • (S)-2-amino-1-(4-methoxyphenyl)ethan-1-ol
  • 108341-18-0
  • 51-41-2;51-40-1
  • C12H17NO9H2O
  • HO2C6H3CHCH2NH2OHC4H6O6H2O
  • C12H17NO9
  • Levophed