4-BROMO-2-METHYLTHIAZOLE
- Product Name
- 4-BROMO-2-METHYLTHIAZOLE
- CAS No.
- 298694-30-1
- Chemical Name
- 4-BROMO-2-METHYLTHIAZOLE
- Synonyms
- 4-Bromo-2-methyl-1,3-thiazole;4-BROMO-2-METHYLTHIAZOLE;Thiazole, 4-bromo-2-methyl-;4-Bromo-2-methylthiazole 98%;4-Bromo-2-(methyl-d3)-thiazole
- CBNumber
- CB3282173
- Molecular Formula
- C4H4BrNS
- Formula Weight
- 178.05
- MOL File
- 298694-30-1.mol
4-BROMO-2-METHYLTHIAZOLE Property
- Boiling point:
- 199.2±13.0 °C(Predicted)
- Density
- 1.702±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- pka
- 0.66±0.10(Predicted)
- form
- liquid
- color
- Colourless
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B697783
- Product name
- 4-Bromo-2-methylthiazole
- Packaging
- 1g
- Price
- $345
- Updated
- 2021/12/16
- Product number
- FB157500
- Product name
- 4-Bromo-2-methylthiazole
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 7H70-9-Z7
- Product name
- 4-Bromo-2-methyl-1,3-thiazole
- Purity
- 95%
- Packaging
- 250mg
- Price
- $56
- Updated
- 2021/12/16
- Product number
- FB157500
- Product name
- 4-Bromo-2-methylthiazole
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FB157500
- Product name
- 4-Bromo-2-methylthiazole
- Packaging
- 250mg
- Price
- $165
- Updated
- 2021/12/16
4-BROMO-2-METHYLTHIAZOLE Chemical Properties,Usage,Production
Synthesis
616-42-2
298694-30-1
General procedure for the synthesis of 2-methyl-4-bromothiazole from dimethyl sulfite: 2,4-dibromothiazole (2.4 g, 9.8 mmol) was dissolved in anhydrous THF (50 mL), and the resulting solution was stirred at -78 °C under argon protection. Slowly n-butyllithium (4.2 mL, 6 mmol, 2.5 M hexane solution) was added and stirring was continued for 1 hour. Subsequently, a solution of dimethyl sulfate (2.7 mL) in THF (5 mL) was added dropwise. The reaction mixture was stirred at -78 °C for 4 h before slowly warming to room temperature and continuing to stir overnight. Upon completion of the reaction, the reaction mixture was diluted with saturated aqueous sodium bicarbonate solution (50 mL). The aqueous layer was extracted with ether, the organic phases were combined, washed with brine, dried over magnesium sulfate and concentrated by rotary evaporation. Finally, purification by silica gel column chromatography afforded 2-methyl-4-bromothiazole as a yellow oil (0.956 g, 55% yield).
References
[1] Patent: WO2007/14922, 2007, A1. Location in patent: Page/Page column 121-122
4-BROMO-2-METHYLTHIAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
4-BROMO-2-METHYLTHIAZOLE Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
- Tel
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- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
- Tel
- --
- Fax
- --
- vernam@fluorochem.co.uk
- Country
- United Kingdom
- ProdList
- 6375
- Advantage
- 65
- Tel
- --
- Fax
- --
- enquiries@fluorochem.co.uk
- Country
- United Kingdom
- ProdList
- 6401
- Advantage
- 74
View Lastest Price from 4-BROMO-2-METHYLTHIAZOLE manufacturers
- Product
- 4-BROMO-2-METHYLTHIAZOLE 298694-30-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-07