H-D-GLU(TRP-OH)-OH

Product Name: H-D-GLU(TRP-OH)-OH
CAS No.: 66471-20-3
Chemical Name: H-D-GLU(TRP-OH)-OH
Synonyms: Scv-07;Scv 07;Bestim;GLU-TRP;GAMMA-GLU-TRP;H-g-Glu-Trp-OH;H-γ-Glu-Trp-OH;H-GLU(TRP-OH)-OH;H-D-gGlu-L-Trp-OH;H-GAMMA-GLU-TRP-OH
CBNumber: CB3287734
Molecular Formula: C16H19N3O5
Formula Weight: 333.34
MOL File: 66471-20-3.mol

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H-D-GLU(TRP-OH)-OH Property

Boiling point:: 737.3±60.0 °C(Predicted)
Density: 1.428
storage temp.: −20°C
pka: 2.22±0.10(Predicted)
Sequence: H-γ-Glu-Trp-OH

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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H-D-GLU(TRP-OH)-OH Chemical Properties,Usage,Production

Uses

Bestim is a dipeptide, which exhibits high affinity to murine peritoneal macrophages, thymocytes, and plasma membranes isolated from these cells, with Kds of 3.1, 2.1, 18.6 and 16.7 nM, respectively. Bestim inhibits adenylate cyclase in the membranes of murine macrophages and thymocytes. Bestim exhibits immunomodulatory efficacy[1].

Definition

ChEBI: A glutamyl-L-amino acid obtained by formal condensation of the gamma-carboxy group of glutamic acid with the amino group of tryptophan.

References

[1] Kolobov AA, et al., Interaction of the synthetic immunomodulatory dipeptide bestim with murine macrophages and thymocytes. Bioorg Khim. 2008 Jan-Feb;34(1):43-9. Russian. DOI:10.1134/s1068162008010044

H-D-GLU(TRP-OH)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-D-GLU(TRP-OH)-OH Suppliers

China 53 Germany 1 Switzerland 1 United Kingdom 1 United States 6 Global 62

GL Biochem (Shanghai) Ltd

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66471-20-3, H-D-GLU(TRP-OH)-OHRelated Search:

Fmoc-Beta-Me-DL-Ile-OH N-ALPHA-TRITYL-L-ASPARAGINE BENZYL N-[2-HYDRAZINO-1-(1H-IMIDAZOL-2-YLMETHYL)-2-OXOETHYL]CARBAMATE (R)-2-Amino-4-oxo-4-(tritylamino)butanoic acid hydrate FMoc-α-Me-D-Asp(OtBu)-OH (9H-Fluoren-9-yl)MethOxy]Carbonyl D-beta-Methylisoleucine FMOC-D-3,4-DIMETHOXYPHENYLALANINE H-GLU-TRP-OH

GLU-TRP

GAMMA-GLU-TRP

H-D-GLU(TRP-OH)-OH

H-GAMMA-GLU-TRP-OH

H-GAMMA-D-GLU-TRP-OH

H-GLU(TRP-OH)-OH

Bestim

L-Tryptophan, L-gamma-glutamyl-

L-Tryptophan, N-L-gamma-glutamyl-

Scv 07

Scv-07

L-gamma-Glutamyl-L-tryptophan

H-g-Glu-Trp-OH

H-D-gGlu-L-Trp-OH

2-amino-5-[[1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid

L-Tryptophan, L-g-glutamyl-

Bestim, 10 mM in DMSO

H-γ-Glu-Trp-OH

66471-20-3

Biochemicals and Reagents

Amino Acids and Peptides

BioChemical

Dipeptides

Dipeptides and Tripeptides

Dipeptides

Dipeptides and Tripeptides

Peptides