SQ 22,536
- Product Name
- SQ 22,536
- CAS No.
- 17318-31-9
- Chemical Name
- SQ 22,536
- Synonyms
- Ax 100;CS-2551;Nsc 53339;9-THF-Ade;SQ 22,536;SQ 22536;SQ-22536;SQ22,536/Inhibitor;SQ22536 (NSC-53339);9-(Tetrahydrofuran-2-yl);Tetrahydrofuryl-9-adenine
- CBNumber
- CB3289950
- Molecular Formula
- C9H11N5O
- Formula Weight
- 205.22
- MOL File
- 17318-31-9.mol
SQ 22,536 Property
- Melting point:
- 160-161℃
- Boiling point:
- 474.8±55.0 °C(Predicted)
- Density
- 1.70±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- H2O: 21 mg/mL
- form
- solid
- pka
- 3.82±0.10(Predicted)
- color
- white to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- S153
- Product name
- SQ 22,536
- Purity
- ≥97% (HPLC), powder
- Packaging
- 5mg
- Price
- $220
- Updated
- 2024/03/01
- Product number
- 568500
- Product name
- SQ 22536
- Purity
- Cell-permeable adenylate cyclase inhibitor.
- Packaging
- 5mg
- Price
- $187
- Updated
- 2024/03/01
- Product number
- Q0105
- Product name
- SQ 22536
- Packaging
- 10MG
- Price
- $156
- Updated
- 2024/03/01
- Product number
- Q0105
- Product name
- SQ 22536
- Packaging
- 50MG
- Price
- $560
- Updated
- 2024/03/01
- Product number
- J67455
- Product name
- SQ 22536
- Purity
- 95%
- Packaging
- 5mg
- Price
- $136
- Updated
- 2023/06/20
SQ 22,536 Chemical Properties,Usage,Production
Description
SQ 22,536 is an inhibitor of adenylyl cyclase with an IC50 value of 13 μM for inhibition of prostaglandin E1-
Uses
SQ 22,536 was used to study the role of adenylate cyclase in differentiation of PC12 cells and in gap junctional intercellular communication in breast cancer cells.
Definition
ChEBI: A nucleoside analogue that is adenine in which the nitrogen at position 9 has been substituted by a tetrahydrofuran-2-yl group. It is an adenylate cyclase inhibitor.
Biological Activity
Inhibitor of adenylyl cyclase (IC 50 = 1.4 μ M). Inhibits PGE 1 -stimulated increases in cAMP levels in intact human platelets.
Biochem/physiol Actions
SQ 22,536 is an effective inhibitor of not only basal but also prosptaglandin E1-activated adenylate cyclase activities in platelets.1 It reverses hyperalgesia contralaterally and ipsilaterally when injected intramuscularly in rats.2
storage
Store at +4°C
SQ 22,536 Preparation Products And Raw materials
Raw materials
Preparation Products
SQ 22,536 Suppliers
- Tel
- 021-61350663 13052117465
- Fax
- 021-61350662
- sales@zehanbiopharma.com
- Country
- China
- ProdList
- 990
- Advantage
- 55
- Tel
- Fax
- 86-21-57758967
- sales@boylechem.com
- Country
- China
- ProdList
- 2923
- Advantage
- 55
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15848
- Advantage
- 69
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- zhangsn@titansci.com
- Country
- China
- ProdList
- 14113
- Advantage
- 59
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 17987
- Advantage
- 64
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
- Country
- China
- ProdList
- 4647
- Advantage
- 58
- Tel
- +86057186818502 13588463833
- Fax
- Pls mail us for more information!
- info@sagechem.com
- Country
- China
- ProdList
- 10269
- Advantage
- 58
- Tel
- 025-58196018 800028039
- Fax
- 025-83453306
- sales@fartop.net
- Country
- China
- ProdList
- 2231
- Advantage
- 55
- Tel
- sales@witofly.com
- Country
- China
- ProdList
- 2867
- Advantage
- 52
- Tel
- 021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7934
- Advantage
- 58
- Tel
- 400-1647117 15221909166
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41438
- Advantage
- 60
- Tel
- 025-58849295 18951903616;
- Fax
- 025-68650336
- info@adooq.cn
- Country
- China
- ProdList
- 2989
- Advantage
- 60
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51471
- Advantage
- 80
- Tel
- 021-52996696,15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
- 4121
- Advantage
- 55
- Tel
- 13951936332 18305166317
- Fax
- -
- info@serpharm.com
- Country
- China
- ProdList
- 494
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9709
- Advantage
- 58
- Tel
- 025-83453382-8005
- Fax
- 025-83453382
- sale@parabiochem.com
- Country
- China
- ProdList
- 9604
- Advantage
- 55
- Tel
- 010-50973130 4009686088
- 3193328036@qq.com
- Country
- China
- ProdList
- 29797
- Advantage
- 68
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131981
- Advantage
- 58
- Tel
- 0550-5196001 15000891977
- Fax
- 0550-5196001
- wj520wjxby@126.com
- Country
- China
- ProdList
- 1832
- Advantage
- 55
- Tel
- 571-85586718 +8613336195806
- Fax
- +86-571-85864795
- sales@capotchem.com
- Country
- China
- ProdList
- 29797
- Advantage
- 60
- Tel
- 025-66113011 13155353615
- Fax
- (7)02557626880
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15396
- Advantage
- 58
- Tel
- 021-61469567 18521078705
- Fax
- 021-61161605
- sales@fdc-chemical.com
- Country
- China
- ProdList
- 20044
- Advantage
- 58
- Tel
- 17368696818
- Country
- China
- ProdList
- 1986
- Advantage
- 58
- Tel
- 021-58958002 18930822973
- Fax
- 021-58958618
- xiaoyangw@gmail.com
- Country
- China
- ProdList
- 2129
- Advantage
- 58
- Tel
- 027-51831887 15337167856
- Fax
- 027-51837635 QQ1165326703
- hubeixinyuanshun@163.com
- Country
- China
- ProdList
- 10305
- Advantage
- 58
- Tel
- 17317130613
- Fax
- QQ3358272972
- 3358272972@qq.com
- Country
- China
- ProdList
- 3238
- Advantage
- 58
- Tel
- 010-62971590 18548936886
- Fax
- 010-62340519
- 3462612863@qq.com
- Country
- China
- ProdList
- 6912
- Advantage
- 58
- Tel
- 15911056312
- liming@bio-fount.com
- Country
- China
- ProdList
- 9730
- Advantage
- 58
- Tel
- 020-31155029 18902330969
- Fax
- 020-31155029
- sales@tomums.cn
- Country
- China
- ProdList
- 4698
- Advantage
- 58
- Tel
- 021-67121386, 800-988-0390
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 5391
- Advantage
- 58
- Tel
- +1-2135480471 +1-2135480471
- sales@sarms4muscle.com
- Country
- China
- ProdList
- 10523
- Advantage
- 58
- Tel
- +86-27-50766799 +8618062016861
- contact@labnetwork.com
- Country
- China
- ProdList
- 19994
- Advantage
- 58
- Tel
- 86-571-88216897,88216896 13588875226
- Fax
- 86-571-88216895
- sales@hzclap.com
- Country
- CHINA
- ProdList
- 6313
- Advantage
- 58
- Tel
- 021-58447131 13564518121
- sales@dcchemicals.com
- Country
- China
- ProdList
- 9414
- Advantage
- 58
- Tel
- 0519-85788828 13775037613
- sales@chemrenpharm.com
- Country
- China
- ProdList
- 3553
- Advantage
- 58
- Tel
- 15151934985
- sales@yingsapharm.com
- Country
- China
- ProdList
- 4299
- Advantage
- 58
- Tel
- 13918779495
- Fax
- QQ1984683225
- sales@lihan-bio.com
- Country
- China
- ProdList
- 609
- Advantage
- 58
- Tel
- 020-020-82000279 18988968278
- Fax
- QQ:3283937693
- sales@ubiochem.com
- Country
- China
- ProdList
- 2357
- Advantage
- 58
- Tel
- 021-38015121 15000105423
- chenjw@absin.cn
- Country
- China
- ProdList
- 24734
- Advantage
- 58
- Tel
- 88888888888
- hongquchem@qq.com
- Country
- China
- ProdList
- 5132
- Advantage
- 58
- Tel
- 2537653158 16621191650
- Fax
- QQ 2537653158
- 2537653158@qq.com
- Country
- China
- ProdList
- 7382
- Advantage
- 58
- Tel
- 0371-0371-55135753 18003832934
- Fax
- QQ:2853979818
- 2853979818@qq.com
- Country
- China
- ProdList
- 10002
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing1@energy-chemical.com
- Country
- China
- ProdList
- 44894
- Advantage
- 58
- Tel
- 021-69568360 18916172912
- order@med-bio.cn
- Country
- China
- ProdList
- 8141
- Advantage
- 58
- Tel
- 17621736375
- Fax
- QQ2865936518
- kai02281558@126.com
- Country
- China
- ProdList
- 140
- Advantage
- 58
- Tel
- 18252089365
- Krain_kerun@163.com
- Country
- China
- ProdList
- 2642
- Advantage
- 58
- Tel
- 13348960310 13348960310
- 3003867561@qq.com
- Country
- China
- ProdList
- 9946
- Advantage
- 58
- Tel
- 021-50967598 02150967598
- sales@abmole.cn
- Country
- China
- ProdList
- 4495
- Advantage
- 58