ChemicalBook > CAS DataBase List > 2-Bromo-5-fluorobenzonitrile

2-Bromo-5-fluorobenzonitrile

Product Name
2-Bromo-5-fluorobenzonitrile
CAS No.
57381-39-2
Chemical Name
2-Bromo-5-fluorobenzonitrile
Synonyms
Bromofluorobenzonitrile2;Bromo-5-fluorobenzonitrile;2-BROMO-5-FLUOROBENZONITRILE;2-Bromo-5-fluorobenzonitrile99%;Benzonitrile, 2-bromo-5-fluoro-;2-Bromo-5-fluorobenzonitrile >2-Bromo-5-fluorobenzonitrile 99%;2-Bromo-5-fluorobenzonitrile, 98+%;2 - broMine - 5 - fluorine benzene nitriles
CBNumber
CB3296947
Molecular Formula
C7H3BrFN
Formula Weight
200.01
MOL File
57381-39-2.mol
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2-Bromo-5-fluorobenzonitrile Property

Melting point:
92-95 °C(lit.)
Boiling point:
251.2±25.0 °C(Predicted)
Density 
1.69±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in methanol.
form 
powder to crystal
color 
White to Yellow to Orange
BRN 
8678330
InChI
InChI=1S/C7H3BrFN/c8-7-2-1-6(9)3-5(7)4-10/h1-3H
InChIKey
MDHNVHCZDCSTMS-UHFFFAOYSA-N
SMILES
C(#N)C1=CC(F)=CC=C1Br
CAS DataBase Reference
57381-39-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,T,Xi
Risk Statements 
20/21/22
Safety Statements 
26-36
RIDADR 
3439
WGK Germany 
3
Hazard Note 
Toxic
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
532754
Product name
2-Bromo-5-fluorobenzonitrile
Purity
95%
Packaging
25g
Price
$261
Updated
2023/01/07
TCI Chemical
Product number
B3010
Product name
2-Bromo-5-fluorobenzonitrile
Purity
>97.0%(GC)
Packaging
5g
Price
$64
Updated
2025/07/31
TCI Chemical
Product number
B3010
Product name
2-Bromo-5-fluorobenzonitrile
Purity
>97.0%(GC)
Packaging
25g
Price
$181
Updated
2025/07/31
TRC
Product number
B684865
Product name
2-Bromo-5-fluorobenzonitrile
Packaging
10g
Price
$140
Updated
2021/12/16
SynQuest Laboratories
Product number
3637-B-25
Product name
2-Bromo-5-fluorobenzonitrile
Purity
99%
Packaging
100g
Price
$192
Updated
2021/12/16
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2-Bromo-5-fluorobenzonitrile Chemical Properties,Usage,Production

Chemical Properties

Colorless solid

Uses

2-Bromo-5-fluorobenzonitrile may be used in the preparation of 5-chloro-4,2?-difluorobiphenyl-2-carbonitrile.

Uses

2-Bromo-5-fluorobenzonitrile is used in the synthesis of pyrimidine functional compounds acting as GABAAα2/α3 binding site agonists used in the treatment of anxiety disorders.

General Description

2-Bromo-5-fluorobenzonitrile can be prepared from 3-fluorobenzonitrile vial bromination using 1,3-dibromo-5,5-dimethylhydantoin (DBDMH).. It undergoes palladium-catalyzed Suzuki coupling with boronic acid derivative to form corresponding biaryl.

2-Bromo-5-fluorobenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-5-fluorobenzonitrile Suppliers

Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
021-31038972,31038973 17321035817
Fax
+86-21-51385350
Email
sales@harvest-chem.com
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China
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
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China
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
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China
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Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
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China
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
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sales@chemwish.com
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China
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35896
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
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China
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Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
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China
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JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
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China
ProdList
9976
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Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
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66
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View Lastest Price from 2-Bromo-5-fluorobenzonitrile manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Bromo-5-fluorobenzonitrile 57381-39-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-15
Career Henan Chemical Co
Product
2-Bromo-5-fluorobenzonitrile 57381-39-2
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

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