2-Fluorobenzonitrile

Synthesis

Product Name: 2-Fluorobenzonitrile
CAS No.: 394-47-8
Chemical Name: 2-Fluorobenzonitrile
Synonyms: FLUOROBENZONITRILE;2-FBN;NSC 88278;uorobenzonitriL;2-fluoronitrile;2-Fluorbenzonitril;O-Fluorobenzonitile;2-Fluorocyanobenzene;2-CYANOFLUOROBENZENE;2-FLUOROBENZONITRILE
CBNumber: CB4680400
Molecular Formula: C7H4FN
Formula Weight: 121.11
MOL File: 394-47-8.mol

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2-Fluorobenzonitrile Property

Melting point:: -13.7 °C
Boiling point:: 90 °C21 mm Hg(lit.)
Density: 1.116 g/mL at 25 °C(lit.)
refractive index: n20/D 1.505(lit.)
Flash point:: 165 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform
form: Liquid
color: Clear colorless to light brownish
Water Solubility: Insoluble
BRN: 2042184
InChIKey: GDHXJNRAJRCGMX-UHFFFAOYSA-N
CAS DataBase Reference: 394-47-8(CAS DataBase Reference)
NIST Chemistry Reference: Benzonitrile, 2-fluoro-(394-47-8)
EPA Substance Registry System: Benzonitrile, 2-fluoro- (394-47-8)

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Safety

Hazard Codes: Xn,T,Xi
Risk Statements: 22-37/38-41-36/37/38-20/21/22
Safety Statements: 26-39-36/37/39-36
RIDADR: 3276
WGK Germany: 3
Hazard Note: Toxic
TSCA: T
HazardClass: IRRITANT, IRRITANT-HARMFUL
PackingGroup: III
HS Code: 29269095

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 196649
Product name: 2-Fluorobenzonitrile
Purity: 98%
Packaging: 5g
Price: $21.4
Updated: 2025/07/31

Sigma-Aldrich

Product number: 196649
Product name: 2-Fluorobenzonitrile
Purity: 98%
Packaging: 25g
Price: $49.4
Updated: 2025/07/31

TCI Chemical

Product number: F0220
Product name: 2-Fluorobenzonitrile
Purity: >98.0%(GC)
Packaging: 25g
Price: $54
Updated: 2025/07/31

TRC

Product number: F588390
Product name: 2-Fluorobenzenenitrile
Packaging: 100g
Price: $295
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0019940
Product name: 2-FLUOROBENZONITRILE
Purity: 95.00%
Packaging: 100G
Price: $455
Updated: 2021/12/16

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2-Fluorobenzonitrile Chemical Properties,Usage,Production

Synthesis

Tetramethylammonium fluoride (TMAF) has been found to be an effective fluorodenitration reagent. The good selectivity for the fluoroaromatic and not the phenol has been attributed to the stability of ion pairing between nitrite and tetramethylammonium ions. TMAF reacts with 2-nitrobenzonitrile to give a quantitative conversion to 2-fluorobenzonitrile.

Chemical Properties

colorless to light yellow liquid

Uses

2-Fluorobenzonitrile, also known as o-fluorobenzonitrile, is an organic aromatic fluoride. It has a wide range of applications in pharmaceuticals, pesticides, dyestuffs, etc. In the field of dyestuff, the introduction of fluorine atom makes the dyed products bright and colorful and less likely to fade, among other advantages.

Uses

2-Fluorobenzonitrile was used in the synthesis of :
3-amino-1,2-benzisoxazoles
6-(acetylaminomethyl)-3-amino-1,2-benzisoxazole
5-(4′-methyl [1, 1′-biphenyl]-2-yl)-1H-tetrazole
xanthone-iminium triflates

General Description

2-Fluorobenzonitrile reacts with lithium N,N-dialkylaminoborohydride reagent to yield 2-(N,N-dialkylamino)benzylamines.

2-Fluorobenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

2-(1H-IMIDAZOL-1-YL)BENZOIC ACID 1H-INDAZOL-3-YLAMINE 2-MORPHOLINOBENZOIC ACID 5-AMINO-2-FLUOROBENZONITRILE 3-Amino-1,2-benzisoxazole 1-(2-CYANOPHENYL)PIPERAZINE

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2-Fluorobenzonitrile Suppliers

Americas 1 Belgium 4 Canada 3 China 403 Europe 6 France 2 Germany 12 India 35 Italy 1 Japan 7 Jordan 1 Mexico 1 Slovakia 1 South Korea 2 Switzerland 2 The Netherlands 1 Ukraine 2 United Kingdom 25 United States 52 Global 561

Zhejiang Zetian Fine Chemical Co., Ltd.

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Email: sales@zetchem.com
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Weifang Siyuan Chemical Co., Ltd.

Tel: 0536-8888106 17663601818
Fax: 0536-8888106
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Hubei Bojie Biotechnology Co., Ltd

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Shandong Chengxu Chemical Co., Ltd

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Tenghong (Shandong) New Material Co., Ltd

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Hubei zhonglong Kangsheng Fine Chemical Co., Ltd

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J & K SCIENTIFIC LTD.

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Email: jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
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Email: market03@meryer.com
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INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
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future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
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View Lastest Price from 2-Fluorobenzonitrile manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Fluorobenzonitrile 394-47-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-11-25

Henan Fengda Chemical Co., Ltd

Product: 2-Fluorobenzonitrile 394-47-8
Price: US $9.00-0.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-23

Honest Joy Holdings Limited

Product: 2-Fluorobenzonitrile 394-47-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.3%
Supply Ability: 100 tons
Release date: 2022-02-21

394-47-8, 2-FluorobenzonitrileRelated Search:

2-Fluoropropiophenone 2-Chlorobenzyl alcohol 2-Fluorobenzaldehyde 2-Bromofluorobenzene ETHYL 2-FLUOROBENZOATE 2-Fluorobenzoic acid 2-Chlorophenylacetic acid 2-Chloromandelic acid 2-Fluorophenylacetic acid 2'-Fluoroacetophenone 2-Chlorobenzonitrile 2'-Chloroacetophenone 2-Chlorobenzyl bromide 1-Fluoro-2-nitrobenzene 2-Chlorobenzaldehyde 2,6-Difluorobenzonitrile 2-Fluoro-6-methoxybenzonitrile 3,4,5,6-Tetrafluorophthalonitrile

2-Fluorocyanobenzene

2-Fluorophenyl Cyanide

NSC 88278

A nitrile o-fluorobenzene

Nitrile o-fluorobenzene

2-Fluorobenzenenitrile

O-Fluorobenzonitile

2-Fluorobenzonitrile, 99% 25GR

2-Fluorobenzonitrile, 99% 5GR

Adjacent fluorobenzene nitrile

Letrozole Impurity 21

FLUOROBENZONITRILE

2-CYANOFLUOROBENZENE

2-FLUOROBENZONITRILE

O-FLUOROBENZONITRILE

Benzonitrile, o-fluoro-

o-Cyanofluorobenzene

o-Fluorobenzonitrile 2-Fluorobenzonitrile

2-FLUOROBENZONITRILE 98% (GC)

2-Fluorobenzonitrile,99%

2-Fluorobenzonitrile 99%

2-Fluorbenzonitril

2-Fluorobenzonitrile ,98%

1-Fluoro-2-cyanobenzene

uorobenzonitriL

2-FBN

2-Fluorobenzonitrile&gt

Benzonitrile, 2-fluoro-

2-fluoronitrile

Ortho fluorobenzonitrile

394-47-8

FC6H4CN

Cyanides/Nitriles

Organic Building Blocks

Nitrogen Compounds

Building Blocks

C6 to C7

Aromatics

Miscellaneous Reagents

FINE Chemical & INTERMEDIATES

Aromatic Nitriles

Fluorobenzene

Nitrile

Fluorine Compounds

Nitriles

C6 to C7

Cyanides/Nitriles

Nitrogen Compounds

Fluorobenzene Series

OLED