2-MORPHOLINOBENZOIC ACID
- Product Name
- 2-MORPHOLINOBENZOIC ACID
- CAS No.
- 42106-48-9
- Chemical Name
- 2-MORPHOLINOBENZOIC ACID
- Synonyms
- AKOS BB-8942;BUTTPARK 98\12-69;RARECHEM AL BO 2105;CHEMBRDG-BB 4006143;2-MORPHOLINOBENZOIC ACID;2-(4-Morpholino)benzoic acid;2-Morpholinobenzoic acid ,97%;2-(4-Morpholinyl)benzoic Acid;2-(MORPHOLIN-4-YL)BENZOIC ACID;Benzoic acid, 2-(4-morpholinyl)-
- CBNumber
- CB2223478
- Molecular Formula
- C11H13NO3
- Formula Weight
- 207.23
- MOL File
- 42106-48-9.mol
2-MORPHOLINOBENZOIC ACID Property
- Melting point:
- 157 °C
- Boiling point:
- 387.5±37.0 °C(Predicted)
- Density
- 1.253±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 2.67±0.36(Predicted)
- Appearance
- Light yellow to light brown Solid
- CAS DataBase Reference
- 42106-48-9
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-37/39
- Hazard Note
- Irritant
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M725228
- Product name
- 2-MorpholinobenzoicAcid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- J90592
- Product name
- 2-Morpholinobenzoicacid
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- OR23383
- Product name
- 2-(4-Morpholino)benzoicacid
- Packaging
- 1g
- Price
- $87
- Updated
- 2021/12/16
- Product number
- 4H21-1-B9
- Product name
- 2-(4-Morpholino)benzoic acid
- Packaging
- 1g
- Price
- $96
- Updated
- 2021/12/16
- Product number
- J90592
- Product name
- 2-Morpholinobenzoicacid
- Packaging
- 250mg
- Price
- $20
- Updated
- 2021/12/16
2-MORPHOLINOBENZOIC ACID Chemical Properties,Usage,Production
Chemical Properties
White to off-white powder
Uses
2-Morpholinobenzoic Acid is used in the preparation of amino acids as inhibitors of αvβ integrin and for treating fibrosis.
Synthesis
192817-79-1
42106-48-9
The general procedure for the synthesis of 2-(4-morpholinyl)benzoic acid from ethyl 2-morpholinobenzoate was as follows: referring to the method of Example 1e, ethyl 2-(morpholin-4-yl)-benzoate was reacted with 2 molar equivalents of sodium hydroxide in methanol solution. After completion of the reaction, the target product 2-(4-morpholinyl)benzoic acid was obtained after post-processing in 90% yield of the theoretical value. The Rf value of the product was 0.75 (silica gel plate; unfolding agent ratio dichloromethane/ethanol/ammonia = 8:4:0.2).
References
[1] Patent: US2003/162788, 2003, A1
[2] Patent: US2003/73836, 2003, A1
[3] Patent: EP1147095, 2004, B1. Location in patent: Page 68
2-MORPHOLINOBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-MORPHOLINOBENZOIC ACID manufacturers
- Product
- 2-Morpholinobenzoic Acid 42106-48-9
- Price
- US $7.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-25
- Product
- 4-(tert-Butyl)-2,6-dimethylaniline 42106-48-9
- Price
- US $7.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-25