ChemicalBook > CAS DataBase List > 2-MORPHOLINOBENZOIC ACID

2-MORPHOLINOBENZOIC ACID

Product Name
2-MORPHOLINOBENZOIC ACID
CAS No.
42106-48-9
Chemical Name
2-MORPHOLINOBENZOIC ACID
Synonyms
AKOS BB-8942;BUTTPARK 98\12-69;RARECHEM AL BO 2105;CHEMBRDG-BB 4006143;2-MORPHOLINOBENZOIC ACID;2-(4-Morpholino)benzoic acid;2-Morpholinobenzoic acid ,97%;2-(4-Morpholinyl)benzoic Acid;2-(MORPHOLIN-4-YL)BENZOIC ACID;Benzoic acid, 2-(4-morpholinyl)-
CBNumber
CB2223478
Molecular Formula
C11H13NO3
Formula Weight
207.23
MOL File
42106-48-9.mol
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2-MORPHOLINOBENZOIC ACID Property

Melting point:
157 °C
Boiling point:
387.5±37.0 °C(Predicted)
Density 
1.253±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
2.67±0.36(Predicted)
Appearance
Light yellow to light brown Solid
CAS DataBase Reference
42106-48-9
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-37/39
Hazard Note 
Irritant
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M725228
Product name
2-MorpholinobenzoicAcid
Packaging
10mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
J90592
Product name
2-Morpholinobenzoicacid
Packaging
5g
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
OR23383
Product name
2-(4-Morpholino)benzoicacid
Packaging
1g
Price
$87
Updated
2021/12/16
SynQuest Laboratories
Product number
4H21-1-B9
Product name
2-(4-Morpholino)benzoic acid
Packaging
1g
Price
$96
Updated
2021/12/16
AK Scientific
Product number
J90592
Product name
2-Morpholinobenzoicacid
Packaging
250mg
Price
$20
Updated
2021/12/16
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2-MORPHOLINOBENZOIC ACID Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

2-Morpholinobenzoic Acid is used in the preparation of amino acids as inhibitors of αvβ integrin and for treating fibrosis.

Synthesis

192817-79-1

42106-48-9

The general procedure for the synthesis of 2-(4-morpholinyl)benzoic acid from ethyl 2-morpholinobenzoate was as follows: referring to the method of Example 1e, ethyl 2-(morpholin-4-yl)-benzoate was reacted with 2 molar equivalents of sodium hydroxide in methanol solution. After completion of the reaction, the target product 2-(4-morpholinyl)benzoic acid was obtained after post-processing in 90% yield of the theoretical value. The Rf value of the product was 0.75 (silica gel plate; unfolding agent ratio dichloromethane/ethanol/ammonia = 8:4:0.2).

References

[1] Patent: US2003/162788, 2003, A1
[2] Patent: US2003/73836, 2003, A1
[3] Patent: EP1147095, 2004, B1. Location in patent: Page 68

2-MORPHOLINOBENZOIC ACID Preparation Products And Raw materials

Raw materials

2-Fluorobenzonitrile Potassium carbonate Hydrochloric acid Methanol Dimethyl sulfoxide Morpholine

Preparation Products

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View Lastest Price from 2-MORPHOLINOBENZOIC ACID manufacturers

Career Henan Chemical Co
Product
2-Morpholinobenzoic Acid 42106-48-9
Price
US $7.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-25
Career Henan Chemical Co
Product
4-(tert-Butyl)-2,6-dimethylaniline 42106-48-9
Price
US $7.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-25

42106-48-9, 2-MORPHOLINOBENZOIC ACIDRelated Search:

2-MORPHOLINOBENZOIC ACID 3-MORPHOLINOBENZOIC ACID 4-(MORPHOLINOMETHYL)BENZOIC ACID 4-MORPHOLINOBENZOIC ACID 5-AMINO-2-MORPHOLIN-4-YL-BENZOIC ACID METHYL ESTER 2-MORPHOLIN-4-YL-5-(PIPERIDINE-1-SULFONYL)-BENZOIC ACID 2-MORPHOLINO-5-(1H-PYRROL-1-YL)BENZOIC ACID METHYL 2-MORPHOLINO-5-NITROBENZENECARBOXYLATE 5-AMINO-2-MORPHOLINOBENZOIC ACID 2-MORPHOLINO-5-NITROBENZOIC ACID METHYL 2-MORPHOLINOBENZOATE 2-MORPHOLIN-4-YL-BENZOIC ACID ETHYL ESTER 2-MORPHOLIN-4-YL-5-(MORPHOLIN-4-YLSULFONYL)BENZOIC ACID 5-[(DIMETHYLAMINO)SULFONYL]-2-MORPHOLIN-4-YLBENZOIC ACID 5-NITRO-2-(2,6-DIMETHYLMORPHOLIN-4-YL)BENZOIC ACID 2-FLUORO-4-MORPHOLINOBENZOIC ACID 2-Methoxy-4-Morpholinobenzoic Acid 2-MORPHOLIN-4-YL-5-(3-THIOPHEN-2-YL-ACRYLOYLAMINO)-BENZOIC ACID

  • 2-MORPHOLINOBENZOIC ACID
  • AKOS BB-8942
  • BUTTPARK 98\12-69
  • CHEMBRDG-BB 4006143
  • RARECHEM AL BO 2105
  • 2-(4-Morpholino)benzoic acid
  • 2-(MORPHOLIN-4-YL)BENZOIC ACID
  • 2-(4-Morpholinyl)benzoic Acid
  • 2-morpholin-4-ylbenzoic acid(SALTDATA: FREE)
  • 2-Morpholinobenzoic acid ,97%
  • Benzoic acid, 2-(4-morpholinyl)-
  • 42106-48-9
  • Acids and Derivatives
  • Heterocycles