4-Morpholinobenzoic acid
- Product Name
- 4-Morpholinobenzoic acid
- CAS No.
- 7470-38-4
- Chemical Name
- 4-Morpholinobenzoic acid
- Synonyms
- AKOS B022043;BUTTPARK 98\50-28;RARECHEM AL BE 1130;TIMTEC-BB SBB007143;CHEMBRDG-BB 4400213;ART-CHEM-BB B022043;OTAVA-BB BB5300270008;4-MorpholinobenzoicAci;4-MORPHOLINOBENZOIC ACID;p-Morpholinobenzoic Acid
- CBNumber
- CB6400336
- Molecular Formula
- C11H13NO3
- Formula Weight
- 207.23
- MOL File
- 7470-38-4.mol
4-Morpholinobenzoic acid Property
- Melting point:
- 278 °C
- Boiling point:
- 413.2±40.0 °C(Predicted)
- Density
- 1.253±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 4.70±0.10(Predicted)
- form
- powder to crystal
- color
- White to Almost white
- Water Solubility
- Slightly soluble in water.
- Sensitive
- Moisture & Light Sensitive
- CAS DataBase Reference
- 7470-38-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 695432
- Product name
- 4-(4-Morpholinyl)benzoic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $46.82
- Updated
- 2025/07/31
- Product number
- M3100
- Product name
- 4-(4-Morpholinyl)benzoic Acid
- Packaging
- 1G
- Price
- $28
- Updated
- 2025/07/31
- Product number
- M3100
- Product name
- 4-(4-Morpholinyl)benzoic Acid
- Packaging
- 5G
- Price
- $84
- Updated
- 2025/07/31
- Product number
- B497260
- Product name
- 4-MorpholinobenzoicAcid
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- OR23266
- Product name
- 4-Morpholin-4-ylbenzoicacid
- Packaging
- 5g
- Price
- $124
- Updated
- 2021/12/16
4-Morpholinobenzoic acid Chemical Properties,Usage,Production
Uses
4-(4-Morpholinyl)benzoic acid, is used as an intermediate in organic synthesis. The water based additive is used in a variety of applications as a heat-sealing and anti-blocking agent.
Definition
ChEBI: 4-morpholinobenzoic acid is a member of morpholines.
Synthesis
110-91-8
451-46-7
7470-38-4
Example 1: Preparation of 4-(4-morpholinyl)benzoic acid by alkaline hydrolysis one-pot method using ethyl 4-fluorobenzoate and morpholine as raw materials. The procedure was as follows: ethyl 4-fluorobenzoate (3.5 g, 21 mmol) was mixed with morpholine (6.2 g, 70 mmol), and the reaction was heated at 130 °C for 12 hours until the ethyl 4-fluorobenzoate was completely converted. Subsequently, water (15 mL) and 20% NaOH solution (10 mL) were added to the reaction mixture and refluxing was continued for 3.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and acidified by adding 5% HCl solution with effective stirring. The precipitate was collected by filtration, washed with water and dried under vacuum at 60 °C to afford 4-morpholino benzoic acid (3.9 g) in 90% yield, melting point 275-277 °C. Mass spectrometric analysis showed the molecular ion peaks m/z 207 (100, M+).1H NMR (DMSO-d6) δ: 12.33 (br s, 1H), 7.78 (d, J=8.5 Hz. 2H), 6.95 (d, J=8.5 Hz, 2H), 3.72 (t, J=4.5 Hz, 2H), 3.23 (t, J=4.5 Hz, 2H).13C NMR (CDCl3) δ: 167.25, 153.90, 130.81, 119.91, 113.22, 65.87, 46.97.
References
[1] Patent: US2003/171581, 2003, A1
4-Morpholinobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Morpholinobenzoic acid manufacturers
- Product
- 4-Morpholinobenzoic acid 7470-38-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25