1H-INDAZOL-3-YLAMINE
Uses- Product Name
- 1H-INDAZOL-3-YLAMINE
- CAS No.
- 874-05-5
- Chemical Name
- 1H-INDAZOL-3-YLAMINE
- Synonyms
- 10P-212;3-Indazolamine;3-AMINOINDAZOLE;1H-INDAZOL-3-AMINE;3-amino-1h-indazole;1H-indazole-3-amine;1H-INDAZOL-3-YLAMINE;1H-Indazole, 3-amino-;1H-Indazole-3-ylamine;Phenol,3,10-dimethoxy-
- CBNumber
- CB0255361
- Molecular Formula
- C7H7N3
- Formula Weight
- 133.15
- MOL File
- 874-05-5.mol
1H-INDAZOL-3-YLAMINE Property
- Melting point:
- 156-157°C
- Boiling point:
- 376.6±15.0 °C(Predicted)
- Density
- 1.367±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 14.89±0.40(Predicted)
- form
- Liquid or Solid
- color
- Clear, colorless or white to pale yellow
- InChI
- InChI=1S/C7H7N3/c8-7-5-3-1-2-4-6(5)9-10-7/h1-4H,(H3,8,9,10)
- InChIKey
- YDTDKKULPWTHRV-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC=C2)C(N)=N1
- CAS DataBase Reference
- 874-05-5(CAS DataBase Reference)
- EPA Substance Registry System
- 1H-Indazol-3-amine (874-05-5)
Safety
- Hazard Codes
- T
- Risk Statements
- 34-25-36/37/38-22
- Safety Statements
- 26-36/37/39-45-22
- RIDADR
- 3259
- TSCA
- Yes
- HazardClass
- 6.1
- HazardClass
- IRRITANT
- PackingGroup
- Ⅲ
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- I509003
- Product name
- 1H-Indazol-3-amine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- I509003
- Product name
- 1H-Indazol-3-amine
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 042721
- Product name
- 1H-Indazol-3-amine
- Purity
- >95%
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- OR30984
- Product name
- 3-Amino-1H-indazole
- Packaging
- 1g
- Price
- $18
- Updated
- 2021/12/16
- Product number
- 3H30-1-U0
- Product name
- 3-Amino-1H-indazole
- Packaging
- 1g
- Price
- $20
- Updated
- 2021/12/16
1H-INDAZOL-3-YLAMINE Chemical Properties,Usage,Production
Uses
1H-Indazol-3-amine is a reagent used in the preparation of indazole derivatives as potential antimicrobial and antitumor agents.
Chemical Properties
Light yellow crystals
Uses
1H-Indazol-3-amine is a reagent used in the preparation of indazole derivatives as potential antimicrobial and antitumor agents.
Definition
ChEBI: 1H-indazol-3-amine is a member of indazoles.
Synthesis
394-47-8
874-05-5
Example 21.1: Preparation of methyl 3-hydroxy-4-oxo-4,6-dihydro-pyrimido[1,2-b]indazole-2-carboxylate Step 1: 2-Fluorobenzonitrile (605 mg, 5 mmol) was mixed with 85% hydrazine hydrate (352 mg, 6 mmol) in 1-butanol (3 mL). The reaction mixture was heated to reflux and stirred for 5 hours. After completion of the reaction, it was cooled to room temperature and the precipitate was collected by filtration. The filter cake was washed with dichloromethane and subsequently dried under vacuum to give 3-aminoindazole (293 mg, 44% yield). 1H NMR (300 MHz, D6-DMSO): δ 5.26-6.36 (brs, 2H), 6.84-6.93 (m, 1H), 7.18-7.24 (m, 2H), 7.67 (dt, J = 8.1, 0.9 Hz, 1H), 11.33 (s, 1H).
References
[1] Chemical Communications, 2014, vol. 50, # 85, p. 12911 - 12914
[2] Advanced Synthesis and Catalysis, 2016, vol. 358, # 13, p. 2126 - 2133
[3] Patent: WO2008/77188, 2008, A1. Location in patent: Page/Page column 127-128
[4] Organic Process Research and Development, 2011, vol. 15, # 3, p. 565 - 569
[5] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 23, p. 5293 - 5297
1H-INDAZOL-3-YLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-INDAZOL-3-YLAMINE manufacturers
- Product
- 3-Indazolamine 874-05-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%minHPLC
- Supply Ability
- 100kg/month
- Release date
- 2021-11-17
- Product
- 1H-INDAZOL-3-YLAMINE 874-05-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 1H-INDAZOL-3-YLAMINE 874-05-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-06-25