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N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine

Product Name
N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine
CAS No.
440327-50-4
Chemical Name
N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine
Synonyms
2'-O-MOE-rG(iBu);2'-O-MOE-N2-ibu-rG;N2-iBu-2'-O-MOE-Gr;N2-ibu-2'-O-MOE-rG;2’-MOE-N2-iBu-Guanosine;N2-Isobutyryl-2'-O-MOE-guanosine;N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine;N2-iso-Butyryl-2’-O-(2-methoxyethyl)guanosine;2'-O-(2-methoxyethyl)-N2-isobutyryl-guanosine;N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine
CBNumber
CB33051730
Molecular Formula
C17H25N5O7
Formula Weight
411.41
MOL File
440327-50-4.mol
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N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine Property

InChIKey
IZOOGJIUOCHAAY-UBEDBUPSSA-N
SMILES
OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OCCOC)[C@@H]1O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Chemenu
Product number
CM230941
Product name
N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
Purity
95+%
Packaging
1g
Price
$3481
Updated
2021/12/16
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N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine Chemical Properties,Usage,Production

Uses

N2-iso-Butyryl-2'-O-(2-methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

References

[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100

N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine Preparation Products And Raw materials

Raw materials

Preparation Products

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N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine Suppliers

Jiangsu Synthgene Biotechnology Co.,Ltd.
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15852554546
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China
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Beijing Ouhe Technology Co., Ltd
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13552068683 13522913783
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+86-10-82967029
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2355560935@qq.com
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China
ProdList
11780
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T&W GROUP
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Nanjing Baifuli Technology Co., Ltd.
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0371-85513397
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Wuhu Nuowei Chemical Technology Co., Ltd
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Shanghai zhigan biotechnology co., LTD
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440327-50-4, N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosineRelated Search:


  • N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine
  • N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
  • N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
  • Guanosine, 2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-
  • 2’-MOE-N2-iBu-Guanosine
  • N2-iBu-2'-O-MOE-Gr
  • 2'-O-(2-methoxyethyl)-N2-isobutyryl-guanosine
  • 2'-O-MOE-rG(iBu)
  • N2-iso-Butyryl-2’-O-(2-methoxyethyl)guanosine
  • N2-Isobutyryl-2'-O-MOE-guanosine
  • 2'-O-MOE-N2-ibu-rG
  • N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
  • N2-ibu-2'-O-MOE-rG
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  • 440327-50-4