ChemicalBook > CAS DataBase List > N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine
N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine
- Product Name
- N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine
- CAS No.
- 256224-04-1
- Chemical Name
- N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine
- Synonyms
- 3'-MOE-N2-iBu-Guanosine;N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine;N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine;Guanosine, 3'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)- (9CI)
- CBNumber
- CB94842162
- Molecular Formula
- C17H25N5O7
- Formula Weight
- 411.41
- MOL File
- 256224-04-1.mol
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N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine Property
- Density
- 1.60±0.1 g/cm3(Predicted)
- pka
- 9.16±0.20(Predicted)
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N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine Chemical Properties,Usage,Production
Uses
N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
References
[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100
N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine Preparation Products And Raw materials
Raw materials
Preparation Products
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