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N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine

Product Name
N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine
CAS No.
256224-04-1
Chemical Name
N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine
Synonyms
3'-MOE-N2-iBu-Guanosine;N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine;N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine;Guanosine, 3'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)- (9CI)
CBNumber
CB94842162
Molecular Formula
C17H25N5O7
Formula Weight
411.41
MOL File
256224-04-1.mol
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N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine Property

Density 
1.60±0.1 g/cm3(Predicted)
pka
9.16±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine Chemical Properties,Usage,Production

Uses

N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

References

[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100

N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine Preparation Products And Raw materials

Raw materials

Preparation Products

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N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine Suppliers

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256224-04-1, N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosineRelated Search:


  • N2-iso-Butyroyl-3'-O-(methoxyethyl)guanosine
  • Guanosine, 3'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)- (9CI)
  • 3'-MOE-N2-iBu-Guanosine
  • N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine
  • 256224-04-1
  • C17H25N5O7