ChemicalBook > CAS DataBase List > 4'-Hydroxy-2,4-dimethoxychalcone

4'-Hydroxy-2,4-dimethoxychalcone

Product Name: 4'-Hydroxy-2,4-dimethoxychalcone
CAS No.: 151135-64-7
Chemical Name: 4'-Hydroxy-2,4-dimethoxychalcone
Synonyms: 4-O-Methylechinatin;4'-Hydroxy-2,dimethoxychalcone;4'-Hydroxy-2,4-dimethoxychalcone;4''-Hydroxy-2,4-dimethoxychalcone;4''-Hydroxy-2,4-dimethoxychalcone, 10 mM in DMSO;(E)-3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one;(2E)-3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one;2-Propen-1-one, 3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)-
CBNumber: CB33054362
Molecular Formula: C17H16O4
Formula Weight: 284.31
MOL File: 151135-64-7.mol

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4'-Hydroxy-2,4-dimethoxychalcone Property

form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN91163
Product name: 4'-Hydroxy-2,4-dimethoxychalcone
Packaging: 10mg
Price: $338
Updated: 2021/12/16

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4'-Hydroxy-2,4-dimethoxychalcone Chemical Properties,Usage,Production

Uses

4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity[1][2].

in vivo

4'-Hydroxy-2,4-dimethoxychalcone (compound 2; oral; 160 mg/kg) has a T_1/2 of 1.94 hours, a C_max of 158 ng/mL and an AUC of 384 ng?h/mL in four- to five-week-old ICR mice^[1].

IC 50

Plasmodium

References

[1] Clare E Gutteridge, et al. In vitro biotransformation, in vivo efficacy and pharmacokinetics of antimalarial chalcones. Pharmacology. 2011;87(1-2):96-104. DOI:10.1159/000322532
[2] Qing-An Zheng, et al. Flavonoids from the Resin of Dracaena cochinchinensis. Helvetica Chimica Acta, 87(5), 1167–1171.

4'-Hydroxy-2,4-dimethoxychalcone Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-Hydroxy-2,dimethoxychalcone

151135-64-7