3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE

Product Name: 3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE
CAS No.: 23165-29-9
Chemical Name: 3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE
Synonyms: 1-Isothiocyanato-3,5-bis(trifluoromethyl)benzene;3,5-Bis(trifuoromethyl)phenyl isothiocyanate;3,5-Di(trifluor;3,5-Trifluoromethylphenyl isothiocyanate;3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYATE;3,5-DI(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE;3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE;3,5-Bis(trifluoromethyl)phenylisothiocyanate97%;3,5-Di(trifluoromethyl)phenyl isothiocyate, 99%;3,5-Bis(trifluoromethyl)phenylIsothiocyanate>
CBNumber: CB3305740
Molecular Formula: C9H3F6NS
Formula Weight: 271.18
MOL File: 23165-29-9.mol

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3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE Property

Melting point:: 160℃
Boiling point:: 63 °C1.5 mm Hg(lit.)
Density: 1.485 g/mL at 25 °C(lit.)
refractive index: n20/D 1.5(lit.)
Flash point:: 228 °F
storage temp.: Storage temp. 2-8°C
form: Liquid
color: Clear yellow
Specific Gravity: 1.485
Water Solubility: Hydrolyzes in water.
Sensitive: Moisture Sensitive
BRN: 2990816
InChI: InChI=1S/C9H3F6NS/c10-8(11,12)5-1-6(9(13,14)15)3-7(2-5)16-4-17/h1-3H
InChIKey: FXOSSGVJGGNASE-UHFFFAOYSA-N
SMILES: C1(N=C=S)=CC(C(F)(F)F)=CC(C(F)(F)F)=C1
CAS DataBase Reference: 23165-29-9(CAS DataBase Reference)

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Safety

Hazard Codes: C,T,Xi
Risk Statements: 34
Safety Statements: 22-26-27-36/37/39-45
RIDADR: 2810
WGK Germany: 3
Hazard Note: Toxic
HazardClass: 6.1
PackingGroup: III
HS Code: 29309090
Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications: Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 468517
Product name: 3,5-Bis(trifluoromethyl)phenyl isothiocyanate
Purity: 98%
Packaging: 1g
Price: $37.62
Updated: 2025/07/31

Sigma-Aldrich

Product number: 468517
Product name: 3,5-Bis(trifluoromethyl)phenyl isothiocyanate
Purity: 98%
Packaging: 5g
Price: $105
Updated: 2025/07/31

TCI Chemical

Product number: I0569
Product name: 3,5-Bis(trifluoromethyl)phenyl Isothiocyanate
Purity: >98.0%(GC)
Packaging: 5g
Price: $55
Updated: 2025/07/31

TCI Chemical

Product number: I0569
Product name: 3,5-Bis(trifluoromethyl)phenyl Isothiocyanate
Purity: >98.0%(GC)
Packaging: 25g
Price: $194
Updated: 2025/07/31

TRC

Product number: T790675
Product name: 3,5-Bis(trifluoromethyl)phenyl isothiocyanate
Packaging: 1g
Price: $75
Updated: 2021/12/16

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3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE Chemical Properties,Usage,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

3,5-Bis(trifluoromethyl)phenyl isothiocyanate has been employed for the following studies:

Chemical derivatization of amino-functionalized model surfaces, amino thiolate on Au, amino siloxane on Si, and polyethylene (PE) foils and films.
Chemical derivatization of self assembled monolayers of ω-amino-4,4′-terphenyl substituted alkanethiols.
Synthesis of ethylene-linked sulfonimidoyl-containing thioureas.
Preparation of pyrrolidine-2-carboxylic acid-{2-[3-(3,5-bistrifluoromethylphenyl)thioureido]phenyl}-amide.

Synthesis

Synthesis of 3,5-bis(trifluoromethyl)phenyl isothiocyanate: 3,5-bis(trifluoromethyl)-4-chloroaniline (25.8g, 132.3mmol), triethylenediamine (44.46g, 396.9mmol) and 135mL toluene were added to a 250mL three-necked flask, and dissolved by stirring at room temperature. Then carbon disulfide (30.06 g, 396.9 mmol) was added dropwise within 2.0 h. After dropping, the reaction was held at 15-25??C for 8-10 h. After the reaction was finished, filtration was carried out, and the filter cake was drenched with 20 mL of toluene once and dried, to obtain the yellowish powdery 3,5-bis(trifluoromethyl)-4-chloroaniline dithiocarbonate. The resulting 3-(trifluoromethyl)-4-chloroaniline dithiocarbonate was suspended in 200 mL of chloroform and cooled to -5-0 ??C with open stirring. Slowly add 60 mL of chloroform dissolved in solid phosgene [bis(trichloromethyl)carbonate, BTC] (12.43 g, 42.0 mmol) dropwise, after dropping, the reaction was carried out in an ice bath for 1 h, and then at room temperature for 1 h. Finally, the reaction was heated to reflux and kept warm for 1.5-2 h. After the reaction, the reaction was cooled down to room temperature, and insoluble material was removed by filtration, and the filtrate was distilled under reduced pressure to obtain 3,5-bis(trifluoromethyl)phenyl 3,5-Bis(trifluoromethyl)phenyl isothiocyanate crude product. After column chromatography (silica gel G, pure petroleum ether elution, concentrated under reduced pressure to obtain light yellow oily liquid 23.5g, purity: 99.6% (GC), bp: 248-251 ??, yield: 80.5%.

3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE Suppliers

Americas 1 Belgium 2 China 157 Europe 1 France 1 Germany 2 India 7 Italy 1 Japan 2 Poland 1 Switzerland 1 United Kingdom 13 United States 22 Global 211

Beijing FYF Chemicals Co., Ltd

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Beijing HwrkChemical Technology Co., Ltd

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Energy Chemical

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Wuhan Chemwish Technology Co., Ltd

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View Lastest Price from 3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE manufacturers

Career Henan Chemical Co

Product: 3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE 23165-29-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2019-08-07

23165-29-9, 3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATERelated Search:

ISOTHIOCYANIC ACID 3,5-BIS(TRIFLUOROMETHYL)PHENYL ESTER

3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE

3,5-DI(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE

3,5-Bis(trifuoromethyl)phenyl isothiocyanate

3,5-Bis(trifluoromethyl)phenyl isothiocyanate, 99+%

3,5-Bis(trifluoromethyl)phenyl isothiocyanate 97%

3,5-Bis(trifluoromethyl)phenylisothiocyanate97%

3,5-Trifluoromethylphenyl isothiocyanate

3,5-Di(trifluoromethyl)phenyl isothiocyanate, 97+%

1,3-Bis(trifluoromethyl)-5-isothiocyanatobenzene

1-Isothiocyanato-3,5-bis(trifluoromethyl)benzene

3,5-Bis(trifluoroMethyl)phenyl isothiocyanate, 99+% 1GR

3,5-Di(trifluoromethyl)phenyl isothiocyate, 99%

3,5-Di(trifluor

3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYATE

3,5-Bis(trifluoromethyl)phenylIsothiocyanate&gt

1-Isothiocyanato-3,5-bis(trifluoromethyl)benzene,>98%

Benzene, 1-isothiocyanato-3,5-bis(trifluoromethyl)-

23165-29-9

CF32C6H3NCS

C9H3F6NS

Building Blocks

Organic Building Blocks

Thiocyanates/Isothiocyanates

Sulfur Compounds

Building Blocks

Chemical Synthesis

Organic Building Blocks

Sulfur Compounds

Fluorine series

Organic Building Blocks

Sulfur Compounds

Thiocyanates/Isothiocyanates

Phenyl isocyanate&Phenyl isothiocyanate