ChemicalBook > CAS DataBase List > Lipoamido-PEG3-Azide

Lipoamido-PEG3-Azide

Product Name
Lipoamido-PEG3-Azide
CAS No.
890016-39-4
Chemical Name
Lipoamido-PEG3-Azide
Synonyms
LA-PEG3-N3;LIPOAMIDO-PEG3-N3;Lipoamido-PEG4-azide;Lipoamido-PEG3-Azide;N-(2-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)ethyl)-5-(1,2-dithiolan-3-yl)pentanamide
CBNumber
CB33062518
Molecular Formula
C16H30N4O4S2
Formula Weight
406.5638
MOL File
890016-39-4.mol
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Lipoamido-PEG3-Azide Property

solubility 
Soluble in DMSO, DMF, DCM
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22516
Product name
Lipoamido-PEG3-azide
Purity
95%
Packaging
250mg
Price
$480
Updated
2021/12/16
Apolloscientific
Product number
BIPG1471
Product name
Lipoamido-PEG3-Azide
Packaging
100mg
Price
$623
Updated
2021/12/16
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Lipoamido-PEG3-Azide Chemical Properties,Usage,Production

Description

Lipoamido-PEG3-azide is a PEG linker comprised of a lipoamide group and a terminal azide group. The azide group can participate in copper-catalyzed Click Chemistry reactions with alkynes, DCBO and BCN reagents to form triazole moieties. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Uses

Lipoamido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] H. Tetsuo Uyeda, et al. Synthesis of surface ligands to prepare hydrophilic and biologically compatible quantum dots. doi: 10.1117/12.590494

Lipoamido-PEG3-Azide Preparation Products And Raw materials

Raw materials

Preparation Products

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