alpha-aMine-oMega-propionic acid hexaethylene glycol
- Product Name
- alpha-aMine-oMega-propionic acid hexaethylene glycol
- CAS No.
- 905954-28-1
- Chemical Name
- alpha-aMine-oMega-propionic acid hexaethylene glycol
- Synonyms
- NH2-PEG6-COOH;Amino-PEG6-COOH;Amino-PEG6-acid;AMINE-PEG6-COOH;amino-dPEG 6-acid;Carboxy-PEG6-amine;Amino-dPEG(R)6-acid;H2N-PEG6-CH2CH2COOH;NH2-PEG6-CH2CH2COOH;Amino-PEG6-propionic acid
- CBNumber
- CB32546868
- Molecular Formula
- C15H31NO8
- Formula Weight
- 353.41
- MOL File
- 905954-28-1.mol
alpha-aMine-oMega-propionic acid hexaethylene glycol Property
- Boiling point:
- 481.0±45.0 °C(Predicted)
- Density
- 1.130±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- form
- solid or viscous liquid
- pka
- 4.28±0.10(Predicted)
- color
- White to Almost white
- InChIKey
- PVRGRRPCHFTMMD-UHFFFAOYSA-N
Safety
- HS Code
- 2942000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- QBD10067
- Product name
- Amino-dPEG®6-acid
- Packaging
- 100MG
- Price
- $138
- Updated
- 2023/06/20
- Product number
- QBD10067
- Product name
- Amino-dPEG®6-acid
- Packaging
- 1000MG
- Price
- $604
- Updated
- 2023/06/20
- Product number
- A2526
- Product name
- 1-Amino-3,6,9,12,15,18-hexaoxahenicosan-21-oic Acid
- Purity
- >95.0%(HPLC)
- Packaging
- 100mg
- Price
- $177
- Updated
- 2024/03/01
- Product number
- A2526
- Product name
- 1-Amino-3,6,9,12,15,18-hexaoxahenicosan-21-oic Acid
- Purity
- >95.0%(HPLC)
- Packaging
- 500mg
- Price
- $517
- Updated
- 2024/03/01
- Product number
- A577198
- Product name
- 1-Amino-3,6,9,12,15,18-hexaoxahenicosan-21-oic Acid
- Packaging
- 2mg
- Price
- $60
- Updated
- 2021/12/16
alpha-aMine-oMega-propionic acid hexaethylene glycol Chemical Properties,Usage,Production
Description
Amino-PEG6-acid is a PEG reagent composing one amine (NH2) and one terminal carboxylic acid group (CO2). The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with activated NHS esters to form a stable amide bond.
Uses
NH2-PEG6-CH2CH2COOH is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
reaction suitability
reagent type: cross-linking reagent
reactivity: carboxyl reactive
IC 50
Cleavable Linker; PEGs
References
[1] Jaume Pons, et al. Engineered polypeptide conjugates and methods for making thereof using transglutaminase. US20130230543A1.
alpha-aMine-oMega-propionic acid hexaethylene glycol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from alpha-aMine-oMega-propionic acid hexaethylene glycol manufacturers
- Product
- 1-Amino-3,6,9,12,15,18-hexaoxahenicosan-21-oic Acid 905954-28-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.9%
- Supply Ability
- 200tons
- Release date
- 2024-04-07
- Product
- Amino-PEG6-COOH 905954-28-1
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >98.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-22
- Product
- alpha-aMine-oMega-propionic acid hexaethylene glycol 905954-28-1
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2020-01-13