Propargyl-PEG2-t-butyl ester
- Product Name
- Propargyl-PEG2-t-butyl ester
- CAS No.
- 1807503-80-5
- Chemical Name
- Propargyl-PEG2-t-butyl ester
- Synonyms
- Propargyl-PEG2-Boc;Propargyl-PEG2-COOtBu;Propargyl-PEG1-C2-COOtBu;Alkyne-PEG2-CH2CH2COOtBu;Propargyl-PEG2-t-Bu Ester;PROPARGYL-PEG2-CH2CH2COOTBU;Propargyl-PEG2-t-butyl ester;3-[2-(2-Boc-ethoxy)ethoxy]-1-propyne;tert-butyl 3-(2-(prop-2-yn-1-yloxy)ethoxy)propanoate;3-(2-(propyl-2-yne-1-yloxy)ethoxy)propanoic acidtertbutyl ester
- CBNumber
- CB33062619
- Molecular Formula
- C12H20O4
- Formula Weight
- 228.28
- MOL File
- 1807503-80-5.mol
Propargyl-PEG2-t-butyl ester Property
- Boiling point:
- 290.5±20.0 °C(Predicted)
- Density
- 1.007±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- P839970
- Product name
- Propargyl-PEG2-t-butylester
- Packaging
- 50mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- P839970
- Product name
- Propargyl-PEG2-t-butylester
- Packaging
- 10mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- BP-22631
- Product name
- Propargyl-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $285
- Updated
- 2021/12/16
- Product number
- AS107935
- Product name
- Propargyl-PEG2-CH2CH2COOtBu
- Purity
- 97%
- Packaging
- 1g
- Price
- $464
- Updated
- 2021/12/16
- Product number
- BP-22631
- Product name
- Propargyl-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $500
- Updated
- 2021/12/16
Propargyl-PEG2-t-butyl ester Chemical Properties,Usage,Production
Description
Propargyl-PEG2-t-butyl ester is a PEG linker that enables Click Chemistry reactions with azide-bearing compounds or biomolecules; copper will be required for catalyzation. Under acidic conditions, the t-butyl group can be removed.
Uses
Propargyl-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Propargyl-PEG2-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG2-t-butyl ester Suppliers
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View Lastest Price from Propargyl-PEG2-t-butyl ester manufacturers
- Product
- Propargyl-PEG2-COOtBu 1807503-80-5
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-03
- Product
- Propargyl-PEG2-COOtBu 1807503-80-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26