ChemicalBook > CAS DataBase List > spacer 18 Phosphoramidite

spacer 18 Phosphoramidite

Product Name: spacer 18 Phosphoramidite
CAS No.: 125607-09-2
Chemical Name: spacer 18 Phosphoramidite
Synonyms: spacer 18 Phosphoramidite;DMT-PEG Phosphoramidite 18;Hexaethylene glycol phosphoramidite;Spacer 18(PEG)-DMT CE Phosphoramidite;1,1-bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite;Phosphoramidous acid, N,N-bis(1-methylethyl)-, 19,19-bis(4-methoxyphenyl)-19-phenyl-3,6,9,12,15,18-hexaoxanonadec-1-yl 2-cyanoethyl ester;3-[2-[2-[2-[2-[2-[2-[bis(4-methoxyphenyl)-phenylmethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
CBNumber: CB33122454
Molecular Formula: C42H61N2O10P
Formula Weight: 784.91
MOL File: 125607-09-2.mol

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spacer 18 Phosphoramidite Property

Boiling point:: 763.6±60.0 °C(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: good in most organic solvents
pka: 3.53±0.70(Predicted)
form: Liquid
color: Colorless to light yellow
Appearance: colorlessoryellowish oil

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: B6709
Product name: 1,1-Bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl 2-Cyanoethyl N,N-Diisopropylphosphoramidite
Packaging: 500MG
Price: $150
Updated: 2025/07/31

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spacer 18 Phosphoramidite Chemical Properties,Usage,Production

Description

Spacer phosphoramidite 18 (hexaethylene glycol phosphoramidite) is an amidite reagent for oligonucleotide synthesis. It provides a long hydrophilic linker that can be used for the synthesis of Scorpion-type qPCR probes, for spacing biotin from oligo strand, and for other applications requiring spatial separation of modifier and oligo

Uses

Hexaethylene glycol phosphoramidite (Spacer Phosphoramidite 18) is an amidite reagent for oligonucleotide synthesis. Hexaethylene glycol phosphoramidite can be used as a linker in synthesis of nucleotide chain and qPCR probes[1][2].

References

[1] Longcheng Li, Moorim KANG. Multi-valent oligonucleotide agent and methods of use thereof. WO2022166849A1
[2] Schaudy E, Lietard J, Somoza MM. Sequence Preference and Initiator Promiscuity for De Novo DNA Synthesis by Terminal Deoxynucleotidyl Transferase. ACS Synth Biol. 2021 Jul 16;10(7):1750-1760. DOI:10.1021/acssynbio.1c00142

spacer 18 Phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

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125607-09-2, spacer 18 PhosphoramiditeRelated Search:

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spacer 18 Phosphoramidite

Spacer 18(PEG)-DMT CE Phosphoramidite

Phosphoramidous acid, N,N-bis(1-methylethyl)-, 19,19-bis(4-methoxyphenyl)-19-phenyl-3,6,9,12,15,18-hexaoxanonadec-1-yl 2-cyanoethyl ester

Hexaethylene glycol phosphoramidite

1,1-bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite

DMT-PEG Phosphoramidite 18

3-[2-[2-[2-[2-[2-[2-[bis(4-methoxyphenyl)-phenylmethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

125607-09-2

C42H61N2O10P

Phosphoramidite