2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE

Product Name: 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE
CAS No.: 5381-99-7
Chemical Name: 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE
Synonyms: 2-Chloro-4H-benzo[d][1,3,2]dioxaphosphinin-4-one;Salicyl Phosphorochloridite;2-CHLORO-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE;2-CHLORO-4H-1,2,3-BENZODIOXAPHOSPHORIN-4-ONE;SALICYLCHLOROPHOSPHITE;SalPCl;NSC 40209;VAN BOOM'S REAGENT;ChloroHbenzodioxaphosphorinone;Salicylchlorophosphite Van Boom's Reagent
CBNumber: CB3312737
Molecular Formula: C7H4ClO3P
Formula Weight: 202.53
MOL File: 5381-99-7.mol

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2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Property

Melting point:: 36-40 °C (lit.)
Boiling point:: 127-128 °C/11 mmHg (lit.)
Flash point:: >230 °F
storage temp.: 2-8°C
solubility: Soluble in acetonitrile, dichloromethane, tetrahydrofuron and dimethylformamide.
form: solid
color: White or Colorless to Orange to Green
BRN: 1311951
Stability:: Water Sensitive
CAS DataBase Reference: 5381-99-7(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 14-34-37
Safety Statements: 26-36/37/39-43-45
RIDADR: UN 3261 8/PG 1
WGK Germany: 3
F: 3-10
Hazard Note: Corrosive
HazardClass: 8
PackingGroup: II
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 324124
Product name: 2-Chloro-1,3,2-benzodioxaphosphorin-4-one
Purity: 95%
Packaging: 5g
Price: $127
Updated: 2024/03/01

Sigma-Aldrich

Product number: 324124
Product name: 2-Chloro-1,3,2-benzodioxaphosphorin-4-one
Purity: 95%
Packaging: 25g
Price: $343
Updated: 2024/03/01

TCI Chemical

Product number: C1210
Product name: 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one
Purity: >95.0%(T)
Packaging: 5g
Price: $59
Updated: 2024/03/01

TCI Chemical

Product number: C1210
Product name: 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one
Purity: >95.0%(T)
Packaging: 25g
Price: $178
Updated: 2024/03/01

Alfa Aesar

Product number: B21086
Product name: 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one, 97%
Packaging: 5g
Price: $68.65
Updated: 2024/03/01

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2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one is a reagent used in phosphorylation and phosphitylation of alcohols and in the formation of H-phosphonates. It is also reactive cyclic phosphitylating reagent involved in fast coupling rates and hydrolytic cleavage more readily compare to that of a acyclic analog.

Uses

2-Chloro-1,3,2-benzodioxaphosphorin-4-one is used as a reagent:

In the phosphorylation and phosphitylation of alcohols.
In the formation of H-phosphonates which are commonly utilized in the synthesis of nucleotides.
To synthesize nucleoside triphosphates by treating with acyl protected nucleoside.

Uses

Highly reactive cyclic phosphitylating reagent which provides fast coupling rates, and hydrolytic cleavage occurs more readily than with acyclic analogs

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE Suppliers

Americas 1 Canada 1 China 86 Europe 1 France 1 Germany 3 India 3 Japan 1 Switzerland 2 United Kingdom 9 United States 13 Global 121

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
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Alfa Aesar

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View Lastest Price from 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one 5381-99-7
Price: US $1.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 tons
Release date: 2020-01-16

5381-99-7, 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONERelated Search:

NAD+ 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one 2-oxide DIMETHYLCHLOROPHOSPHITE 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE

VAN BOOM'S REAGENT

SALICYLCHLOROPHOSPHITE

2-CHLORO-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE

2-CHLORO-4H-1,2,3-BENZODIOXAPHOSPHORIN-4-ONE

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE

2-chloro-1,3,2-benzodioxaphosphonic heterocyclohexane-4-one

ChloroHbenzodioxaphosphorinone

2-Chloro-4H-1,2,3-benzodioxaphosphorin-4-one 90%

2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE 97%

NSC 40209

Salicyl Phosphorochloridite

Salicylchlorophosphite Van Boom's Reagent

2-Chloro-4H-benzo[d][1,3,2]dioxaphosphinin-4-one

2-Chloro-4H-1,3,2-benzodioxaphosphinin-4-one

2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one, Salicyl chlorophosphite

SalPCl

2-Chloro-1,3,2-benzodioxaphosphorin-4-one 95%

2-Chloro-4<i>H</i>-1,3,2-benzodioxaphosphorin-4-one

2-chloro-1,3,2-benzodioxaphosphinin-4-one

2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one,97%

4H-1,3,2-Benzodioxaphosphorin-4-one,2-chloro-

2-Chloro-4H-1,3,2-benzodioxaphosphinin-4-one 95%

2-chloro-2,4-dihydro-1,3,2-benzodioxaphosphinin-4-one

2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one &gt

2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one (90%)

"2-Chloro-4H-1,2,3-benzodioxaphosphorin-4-one 90%"

5381-99-7 2-CHLORO-4H-1,3,2-BENZODIOXAPHOSPHORIN-4-ONE C7H4ClO3P

5381-99-7

C7H4ClO3P

Phosphorylating Agents

Phosphorylation

DNA / RNA Synthesis

Catalysis and Inorganic Chemistry

Phosphorus Compounds

Phosphorus Precursors

Phospholipids - 13C & 2H

Biochemistry

Nucleosides, Nucleotides & Related Reagents

Phosphorylating and Phosphorothioating Agents

Phosphorylation

Protecting Agents, Phosphorylating Agents & Condensing Agents

Synthetic Organic Chemistry

Phosphorylating and Phosphitylating Agents