(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

ChemicalBook > CAS DataBase List > (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

Product Name: (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
CAS No.: 1700622-08-7
Chemical Name: (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
Synonyms: Ezetimibe-10;Ezetimibe Impurity L;Ezetimibe Impurity J;Ezetimibe Impuriry J;(3R,4S)-1-(4-chlorophenyl);1-(4-Chloropheneyl)ezetimibe;(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one;2-Azetidinone, 1-(4-chlorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-;(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one? (Ezetimibe Impurity）;Ezetimibe impuriry 12/N-Des(4-Fluorophenyl)-N-(3-chlorophenyl)-ezetimibe/(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
CBNumber: CB33128951
Molecular Formula: C24H21ClFNO3
Formula Weight: 425.88
MOL File: 1700622-08-7.mol

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(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Property

Boiling point:: 676.0±55.0 °C(Predicted)
Density: 1.354±0.06 g/cm3(Predicted)
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 9.72±0.30(Predicted)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: D292320
Product name: N-Des(4-Fluorophenyl)-N-(3-chlorophenyl)-ezetimibe
Packaging: 100mg
Price: $1190
Updated: 2021/12/16

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(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Chemical Properties,Usage,Production

Uses

N-Des(4-Fluorophenyl)-N-(3-chlorophenyl)-ezetimibe is a derivative of Ezetimibe (E975000), which is an antihyperlipoproteinemic and a cholesterol absorption inhibitor.

(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1700622-08-7, (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-oneRelated Search:

(S)-(+)-4-Phenyl-2-oxazolidinone Ezetimibe-13C6 (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one Ezetimibe Impurity 55 EzetiMibe Dehydoxy IMpurity Ezetimibe N,N'-Diisopropylcarbodiimide EzetiMibe-d4 EZETIMIBE-D4 EZETIMIBE HYDROXY GLUCURONIDE (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One (S)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one Ezetimibe Benzyl Impurity (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one Ezetimibe Related Impurity 7 4-Fluoroaniline Ulipristal Acetate ent-EzetiMibe

(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

Ezetimibe Impurity J

Ezetimibe Impurity L

Ezetimibe impuriry 12/N-Des(4-Fluorophenyl)-N-(3-chlorophenyl)-ezetimibe/(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

Ezetimibe-10

(3R,4S)-1-(4-chlorophenyl)

2-Azetidinone, 1-(4-chlorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-

1-(4-Chloropheneyl)ezetimibe

Ezetimibe Impuriry J

(3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one? (Ezetimibe Impurity）

1700622-08-7

C24H21ClFNO3