Eplerenone EP Impurity B

Product Name: Eplerenone EP Impurity B
CAS No.: 192704-82-8
Chemical Name: Eplerenone EP Impurity B
Synonyms: Eplerenone Impurity B;Eplerenone EP Impurity B;Eplerenone Impurity 4(Eplerenone EP Impurity B);11alpha,12alpha-Epoxy-7alpha-(methoxycarbonyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone;(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester;Pregn-4-ene-7,21-dicarboxylic acid, 11,12-epoxy-17-hydroxy-3-oxo-, 21,17-lactone, 7-methyl ester, (7α,11α,12α,17α)-;(1R,3aS,3bS,4R,9aR,9bS,9cS,10aR,10bR)-Methyl 9a,10b-dimethyl-5',7-dioxo-2,3,3a,3b,4,4',5,5',7,8,9,9a,9b,9c,10a,10b-hexadecahydro-3'H-spiro[cyclopenta[1,2]phenanthro[3,4-b]oxirene-1,2'-furan]-4-carboxylate (Eplerenone Impurity)
CBNumber: CB33133904
Molecular Formula: C24H30O6
Formula Weight: 414.4914
MOL File: 192704-82-8.mol

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Eplerenone EP Impurity B Property

Boiling point:: 592.6±50.0 °C(Predicted)
Density: 1.30±0.1 g/cm3(Predicted)
solubility: Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: E589325
Product name: (7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylicAcidLactone,MethylEster
Packaging: 1mg
Price: $165
Updated: 2021/12/16

TRC

Product number: E589325
Product name: (7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylicAcidLactone,MethylEster
Packaging: 10mg
Price: $1320
Updated: 2021/12/16

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Eplerenone EP Impurity B Chemical Properties,Usage,Production

Uses

(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester is an impurity of eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

Eplerenone EP Impurity B Preparation Products And Raw materials

Raw materials

Preparation Products

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192704-82-8, Eplerenone EP Impurity BRelated Search:

Delta 9,11-canrenone Eplerenone intermediate A1 11-alpha-Hydroxycarvenone (7a,17a)-17-Hydroxy-3-oxo-pregna-4,9(11)-diene-7,21-dicarboxylicacid g-lactone methyl ester Eplerenone Hydroxyacid Potassium Salt Eplerenone EP Impurity A Canrenone Eplerenone 11-a-Hydroxy canrenone methyl ester Eplerenone Impurity 14 6-B-HYDROXY EPLERENONE Eplerenone Impurity 3 SC 25152 (7β,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid γ-Lactone Methyl Ester Eplerenone 7-Carboxylic Acid Impurity Eplerenone Impurity 13(Eplerenone EP Impurity F) Eplerenone Impurity 7 Eplerenone impurity G

Eplerenone EP Impurity B

Eplerenone Impurity B

Eplerenone Impurity 4(Eplerenone EP Impurity B)

(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester

Pregn-4-ene-7,21-dicarboxylic acid, 11,12-epoxy-17-hydroxy-3-oxo-, 21,17-lactone, 7-methyl ester, (7α,11α,12α,17α)-

(1R,3aS,3bS,4R,9aR,9bS,9cS,10aR,10bR)-Methyl 9a,10b-dimethyl-5',7-dioxo-2,3,3a,3b,4,4',5,5',7,8,9,9a,9b,9c,10a,10b-hexadecahydro-3'H-spiro[cyclopenta[1,2]phenanthro[3,4-b]oxirene-1,2'-furan]-4-carboxylate (Eplerenone Impurity)

11alpha,12alpha-Epoxy-7alpha-(methoxycarbonyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone

192704-82-8