Eplerenone EP Impurity A

Product Name: Eplerenone EP Impurity A
CAS No.: 209253-67-8
Chemical Name: Eplerenone EP Impurity A
Synonyms: Eplerenone Impurity A;Eplerenone EP Impurity A;Eplerenone Impurity 6(Eplerenone EP Impurity A);(7α,17α)-9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylicAcidDi-γ-lactone;(7α,17α)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone;(2''S)-3'',4''-Dihydro-3,5''-dioxospiro[androst-4-ene-17,2′-furan]-7α,9α-carbolactone;Pregn-4-ene-7,21-dicarboxylic acid, 9,17-dihydroxy-3-oxo-, 7,9:21,17-dilactone, (7α,17α)-;(7Alpha,17Alpha)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic acid di-gamma-lactone;(2'R,7R,8R,9R,10S,13S,14S)-10,13-Dimethyl-7,8,11,12,13,14,15,16-octahydro-1H,3'H-spiro[9,7-(epoxymethano)cyclopenta[a]phenanthrene-17,2'-furan]-3,5',19(2H,4'H,6H,10H)-trione (Eplerenone Impurity)
CBNumber: CB72645626
Molecular Formula: C23H28O5
Formula Weight: 384.47
MOL File: 209253-67-8.mol

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Eplerenone EP Impurity A Property

Boiling point:: 632.9±55.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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Eplerenone EP Impurity A Chemical Properties,Usage,Production

Uses

(7a,17a)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone is an eplerenone (E588775) impurity. Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

Eplerenone EP Impurity A Preparation Products And Raw materials

Raw materials

Preparation Products

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Eplerenone EP Impurity A Suppliers

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209253-67-8, Eplerenone EP Impurity ARelated Search:

11-a-Hydroxy canrenone methyl ester SC 25152 11-alpha-Hydroxycarvenone Eplerenone intermediate A1 Eplerenone Impurity 3 6-B-HYDROXY EPLERENONE Eplerenone Impurity 14 Eplerenone EP Impurity B Canrenone Delta 9,11-canrenone Spironolactone Eplerenone 7-Carboxylic Acid Impurity Eplerenone (7β,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid γ-Lactone Methyl Ester Eplerenone Hydroxyacid Potassium Salt (7a,17a)-17-Hydroxy-3-oxo-pregna-4,9(11)-diene-7,21-dicarboxylicacid g-lactone methyl ester Eplerenone Impurity 13(Eplerenone EP Impurity F) Eplerenone Impurity 7

Eplerenone EP Impurity A

Eplerenone Impurity A

(7α,17α)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Di-γ-lactone

Eplerenone Impurity 6(Eplerenone EP Impurity A)

Pregn-4-ene-7,21-dicarboxylic acid, 9,17-dihydroxy-3-oxo-, 7,9:21,17-dilactone, (7α,17α)-

(2''S)-3'',4''-Dihydro-3,5''-dioxospiro[androst-4-ene-17,2′-furan]-7α,9α-carbolactone

(2'R,7R,8R,9R,10S,13S,14S)-10,13-Dimethyl-7,8,11,12,13,14,15,16-octahydro-1H,3'H-spiro[9,7-(epoxymethano)cyclopenta[a]phenanthrene-17,2'-furan]-3,5',19(2H,4'H,6H,10H)-trione (Eplerenone Impurity)

(7α,17α)-9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylicAcidDi-γ-lactone

(7Alpha,17Alpha)- 9,17-Dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic acid di-gamma-lactone

209253-67-8