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Eplerenone EP Impurity B

Product Name
Eplerenone EP Impurity B
CAS No.
192704-82-8
Chemical Name
Eplerenone EP Impurity B
Synonyms
Eplerenone Impurity B;Eplerenone EP Impurity B;Eplerenone Impurity 4(Eplerenone EP Impurity B);11alpha,12alpha-Epoxy-7alpha-(methoxycarbonyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone;(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester;Pregn-4-ene-7,21-dicarboxylic acid, 11,12-epoxy-17-hydroxy-3-oxo-, 21,17-lactone, 7-methyl ester, (7α,11α,12α,17α)-;(1R,3aS,3bS,4R,9aR,9bS,9cS,10aR,10bR)-Methyl 9a,10b-dimethyl-5',7-dioxo-2,3,3a,3b,4,4',5,5',7,8,9,9a,9b,9c,10a,10b-hexadecahydro-3'H-spiro[cyclopenta[1,2]phenanthro[3,4-b]oxirene-1,2'-furan]-4-carboxylate (Eplerenone Impurity);(1R,3aS,3bS,4R,9aR,9bS,9cS,10aR,10bR)-Methyl 9a,10b-dimethyl-5',7-dioxo-2,3,3a,3b,4,4',5,5',7,8,9,9a,9b,9c,10a,10b-hexadecahydro-3'H-spiro[cyclopenta[1,2]phenanthro[3,4-b]oxirene-1,2'-furan]-4-carboxylate (Eplerenone Impurity)
CBNumber
CB33133904
Molecular Formula
C24H30O6
Formula Weight
414.4914
MOL File
192704-82-8.mol
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Eplerenone EP Impurity B Property

Boiling point:
592.6±50.0 °C(Predicted)
Density 
1.30±0.1 g/cm3(Predicted)
solubility 
Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
E589325
Product name
(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylicAcidLactone,MethylEster
Packaging
1mg
Price
$165
Updated
2021/12/16
TRC
Product number
E589325
Product name
(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylicAcidLactone,MethylEster
Packaging
10mg
Price
$1320
Updated
2021/12/16
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Eplerenone EP Impurity B Chemical Properties,Usage,Production

Uses

(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester is an impurity of eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

Eplerenone EP Impurity B Preparation Products And Raw materials

Raw materials

Preparation Products

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Eplerenone EP Impurity B Suppliers

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192704-82-8, Eplerenone EP Impurity BRelated Search:


  • Eplerenone EP Impurity B
  • Eplerenone Impurity B
  • Eplerenone Impurity 4(Eplerenone EP Impurity B)
  • (7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester
  • Pregn-4-ene-7,21-dicarboxylic acid, 11,12-epoxy-17-hydroxy-3-oxo-, 21,17-lactone, 7-methyl ester, (7α,11α,12α,17α)-
  • (1R,3aS,3bS,4R,9aR,9bS,9cS,10aR,10bR)-Methyl 9a,10b-dimethyl-5',7-dioxo-2,3,3a,3b,4,4',5,5',7,8,9,9a,9b,9c,10a,10b-hexadecahydro-3'H-spiro[cyclopenta[1,2]phenanthro[3,4-b]oxirene-1,2'-furan]-4-carboxylate (Eplerenone Impurity)
  • 11alpha,12alpha-Epoxy-7alpha-(methoxycarbonyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
  • (1R,3aS,3bS,4R,9aR,9bS,9cS,10aR,10bR)-Methyl 9a,10b-dimethyl-5',7-dioxo-2,3,3a,3b,4,4',5,5',7,8,9,9a,9b,9c,10a,10b-hexadecahydro-3'H-spiro[cyclopenta[1,2]phenanthro[3,4-b]oxirene-1,2'-furan]-4-carboxylate (Eplerenone Impurity)
  • 192704-82-8