ChemicalBook > CAS DataBase List > Quinoline-5-carboxaldehyde

Quinoline-5-carboxaldehyde

Product Name
Quinoline-5-carboxaldehyde
CAS No.
22934-41-4
Chemical Name
Quinoline-5-carboxaldehyde
Synonyms
5-Formylquinoline;AKOS BBS-00005336;CHEMBRDG-BB 4300479;RARECHEM AK ML 0025;5-Quinolinecarbaldehyde;QUINOLINE-5-CARBALDEHYDE;5-QUINOLINECARBOXALDEHYDE;QUINOLINE-5-CARBOXALDEHYDE;Quinoline-5-carbaldehyde(QUC);Quinoline-5-carboxaldehyde, 97+%
CBNumber
CB3323737
Molecular Formula
C10H7NO
Formula Weight
157.17
MOL File
22934-41-4.mol
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Quinoline-5-carboxaldehyde Property

Melting point:
95-96°C
Boiling point:
314.3±15.0 °C(Predicted)
Density 
1.223±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
pka
3.94±0.12(Predicted)
Appearance
Yellow to brown Solid
Water Solubility 
Slightly soluble in water.
Sensitive 
Air Sensitive
BRN 
113095
CAS DataBase Reference
22934-41-4(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38-43
Safety Statements 
26-36/37/39-36/37
HazardClass 
IRRITANT
HS Code 
2933499090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
Q990025
Product name
Quinoline-5-carbaldehyde
Packaging
100mg
Price
$75
Updated
2021/12/16
BroadPharm
Product number
BP-20325
Product name
QUINOLINE-5-CARBALDEHYDE
Purity
97%
Packaging
1g
Price
$186
Updated
2021/12/16
Matrix Scientific
Product number
054396
Product name
Quinoline-5-carbaldehyde
Packaging
500mg
Price
$205
Updated
2021/12/16
AK Scientific
Product number
Y8352
Product name
Quinoline-5-carbaldehyde
Packaging
5g
Price
$1011
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0999338
Product name
5-FORMYLQUINOLINE
Purity
95.00%
Packaging
5MG
Price
$498.94
Updated
2021/12/16
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Quinoline-5-carboxaldehyde Chemical Properties,Usage,Production

Uses

Quinoline-5-carboxaldehyde is used as a precursor in the preparation of pharmaceuticals.

Synthesis

4964-71-0

68-12-2

22934-41-4

General method: n-Butyllithium (2.5 M hexane solution, 300 μL, 0.72 mmol) was added slowly and dropwise to a solution of anhydrous THF (1.5 mL) of 5-bromoquinoline (100 mg, 0.48 mmol) at -78°C. The reaction solution turned red immediately. The reaction solution immediately turned red, followed by the addition of N,N-dimethylformamide (192 μL, 2.49 mmol). After maintaining the reaction temperature at -78 °C with stirring for 10 min, the reaction was quenched with deionized water (6 mL). The reaction mixture was poured into saturated aqueous sodium bicarbonate solution (10 mL) and extracted with ethyl acetate (3 × 10 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: n-hexane solution of 10% ethyl acetate) to give 5-quinolinecarboxaldehyde as a yellow solid in 53% yield.

References

[1] European Journal of Medicinal Chemistry, 2019, p. 290 - 320

Quinoline-5-carboxaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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Quinoline-5-carboxaldehyde Suppliers

Alchem Pharmtech,Inc.
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United States
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Anichem LLC
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ChemFocus, LLC
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View Lastest Price from Quinoline-5-carboxaldehyde manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Quinoline-5-carboxaldehyde 22934-41-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-02-23
Career Henan Chemical Co
Product
Quinoline-5-carboxaldehyde 22934-41-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-26

22934-41-4, Quinoline-5-carboxaldehydeRelated Search:


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