DIGITONIN

Product Name: DIGITONIN
CAS No.: 11024-24-1
Chemical Name: DIGITONIN
Synonyms: itonin;DIGITIN;igitonin;DIGITONIN;DigitoninGr;5% Digitonin;Digitonin, AR;DIGITONIN(RG);Digitonin USP;DIGITONIN TECH
CBNumber: CB3331307
Molecular Formula: C56H92O29
Formula Weight: 1229.31
MOL File: 11024-24-1.mol

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DIGITONIN Property

Melting point:: 230-240 °C (dec.)(lit.)
alpha: D20 -54° (0.45 g in 15.8 ml methanol)
Boiling point:: 788.4°C (rough estimate)
Density: 1.1421 (rough estimate)
refractive index: -52 ° (C=1, EtOH)
storage temp.: Sealed in dry,Room Temperature
solubility: H₂O: 10 mg/mL at 95 °C hot, clear, colorless
pka: 12.68±0.70(Predicted)
form: White powder
color: white
optical activity: [α]20/D 54°, c = 2.8 in methanol(lit.)
Merck: 14,3161
BRN: 78654
Stability:: Hygroscopic
InChIKey: FAAZZWIYYDUONB-JYIJKGCVSA-N
EPA Substance Registry System: Digitonin (11024-24-1)

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Safety

Hazard Codes: T
Risk Statements: 23/24/25
Safety Statements: 22-28-36/37-45
RIDADR: UN 3462 6.1/PG 3
WGK Germany: 3
RTECS: IH2050050
F: 3-10
HazardClass: 6.1(a)
PackingGroup: II
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D141
Product name: Digitonin
Purity: Used as non-ionic detergent
Packaging: 100mg
Price: $82
Updated: 2024/03/01

Sigma-Aldrich

Product number: D141
Product name: Digitonin
Purity: Used as non-ionic detergent
Packaging: 500mg
Price: $276
Updated: 2024/03/01

TCI Chemical

Product number: D0540
Product name: Digitonin
Packaging: 100mg
Price: $95
Updated: 2024/03/01

Cayman Chemical

Product number: 14952
Product name: Digitonin
Packaging: 100mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 14952
Product name: Digitonin
Packaging: 1g
Price: $435
Updated: 2024/03/01

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DIGITONIN Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

enhances membrane permeability

Uses

Natural surfactant useful for receptor solubilization and cell permeabilization, e.g., blood platelets, hepatocytes, yeast or tumor cells

Uses

Digitonin has been used in a study to assess a procedure for isolating mitochondria from ascites tumor cells. It has also been used in a study to investigate its effect on the cytotoxicity of plant secondary metabolites in cancer cells. This mild nonionic detergent can be used to solubilize receptors and permeabilize cellular and nuclear membranes.

Uses

Clinical reagent (cholesterol determination).

General Description

Crystals or white powder.

Air & Water Reactions

Forms soapy aqueous suspension .

Reactivity Profile

DIGITONIN is incompatible with strong oxidizing agents and strong acids. (NTP, 1992

Fire Hazard

Flash point data for DIGITONIN are not available; however, DIGITONIN is probably combustible.

Safety Profile

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Mutation data reported. See also DIGITALIS. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

This digitoxin hexa-glycoside can be recrystallised from aqueous 85% EtOH or MeOH/diethyl ether. It is purified by preparative paper chromatography and developed with the upper phase of a mixture of nBuOH/H2O/AcOH (4:5:1), and the spot (RF 0.36) is eluted with 25% CCl3CO2H in CHCl3. It has also been purified by countercurrent distribution. It forms an ethanolate, and complexes with cholesterol and other sterols. [Ruhenstroth-Bauer & Breitenfeld Hoppe Seyler's Z Physiol Chem 302 111 1955, Grisvold J Am Pharm Assoc 23 664 1934, Beilstein 19 IV 1243.]

DIGITONIN Preparation Products And Raw materials

Raw materials

Preparation Products

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DIGITONIN Suppliers

Americas 1 Belgium 1 China 183 Czech Republic 1 Europe 4 France 2 Germany 8 India 22 Italy 1 Japan 6 Poland 1 Switzerland 5 United Kingdom 13 United States 45 Global 293

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

BeiJing Hwrk Chemicals Limted

Tel: 0757-86329057 18501085097
Fax: 010-89508210
Email: sales3.gd@hwrkchemical.com
Country: China
ProdList: 7583
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9984
Advantage: 60

Nanjing Habo Medical Technology Co., Ltd.

Tel: 025-85760892 13376090521
Fax: 025-85766769
Email: sales@habotech.com
Country: China
ProdList: 999
Advantage: 60

Shandong Xiya Chemical Co., Ltd

Tel: 13355009207 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18739
Advantage: 57

BEST-REAGENT

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11726
Advantage: 57

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View Lastest Price from DIGITONIN manufacturers

Henan Fengda Chemical Co., Ltd

Product: DIGITONIN 11024-24-1
Price: US $8.00-0.80/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

Career Henan Chemical Co

Product: DIGITONIN 11024-24-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1
Release date: 2018-08-06

11024-24-1, DIGITONINRelated Search:

TRIPROPYLENE GLYCOL MONOMETHYL ETHER 2-Methylundecanal dimethylacetal 1,1-Dimethoxydecane LAURYL ALDEHYDE DIMETHYL ACETAL ISOVERTAL 411 L N-OCTYL-BETA-D-GLUCOPYRANOSIDE 2-Octyl-1-dodecanol DIGITONIN Tigogenin HEPTANAL-DIETHYLACETAL 5α-Cholestane CIS-1,2-CYCLOPENTANEDIOL KOHINOOL Dihydrocholesterol (25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL TRIGLYCEROL 3-BUTOXY-PROPIONALDEHYDE DIETHYL ACETAL ISOGRISAL 7 C

25R,5ALPHA-SPIROSTAN-2ALPHA,3BETA,15BETA-TRIOL 3BETA-O-BETA-D-GALACTOPYRANOSYL-(1->3)-O-BETA-D-GALACTYOPYRANOSYL-(1->2)-O-BETA-D-[3-O-BETA-D-XYLOPYRANOSYL]-(1->4)-O-BETA-D-GALACTOPYRANOSIDE

DIGITONIN CRYSTALLINE

Digitonin, High Purity

DIGITONIN (DIGITIN) HIGH PURITY RECEPTOR SOLUBILIZING

DigitoninGr

Digitonin, AR

DIGITONIN, USED AS NON-IONIC DETERGE

beta.-D-Galactopyranoside, (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1?3)-O-.beta.-D-galactopyranosyl-(1?2)-O-.beta.-D-xylopyranosyl-(1?3)-O-.beta.-D-glucopyranosyl-(1?4)-

(2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1 .beta.-D-Galactopyranoside

DIGITONIN TECH

DIGITONIN,CRYSTAL,REAGENT

DIGITONIN(RG)

(1→3)]-O-β-D-glucopyranosyl-(1→4)- β-D-

(2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-ylO-.beta.-D-glucopyranosyl-(1.beta.-D-Galactopyranoside

beta-d-galactopyranoside,(2alpha,3beta,5alpha,15beta,25theta)-2,15-dihyd

osyl-(1.fwdarw.2)-o-[beta-d-xylopyranosyl-(1.fwdarw.3)]-o-beta-d-glucopyranos

roxyspirostan-3-ylo-beta-d-glucopyranosyl-(1.fwdarw.3)-o-beta-d-galactopyran

yl-(1.fwdarw.4)-

Digitonin ,50%

2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl-O-β-D-glucopyranosyl-1β-D-Galactopyranoside

DIGITIN

DIGITONIN

DIGITONIN, ALCOHOL-SOLUBLE

DIGITONIN WATER SOLUBLE

Digitogenin,3-[O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl-

galactopyranoside]

Digitonin, approx. 50% (TLC)

[(25R)-2α,15β-Dihydroxy-5α-spirostan-3β-yl]4-O-[2-O-[3-O-(β-D-glucopyranosyl)-β-D-galactopyranosyl]-3-O-(β-D-xylopyranosyl)-β-D-glucopyranosyl]-β-D-galactopyranoside

Digitonin, approx. 50% (TLC) 500MG

Digitonin, approx. 50% (TLC) 5GR

DIGITONINANALYTICAL GRADE

DIGITONIN WATER SOLUBLERESEARCH GRADE

Digitonin,Digitin

Digitonin, approx. 50%, water soluble

5% Digitonin

Digitonin USP

itonin

β-D-Galactopyranoside, (2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-

Digitonin (Digitin) extrapure, 50%

3-Benzoxazole-6-carboxylic acid

igitonin

Digitonin (8CI)

11024-24-1

C56H92O29

C56H92O28

Sterols

Lipids

Non-Ionic

Detergents

Conjugates

Biochemicals and Reagents

BioChemical

Surfactants (for Biochemistry)

Sugars

Nonionic Surfactants (for Biochemistry)

Glycosides

Steroids

Steroidglycosides