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DIGITONIN

Product Name
DIGITONIN
CAS No.
11024-24-1
Chemical Name
DIGITONIN
Synonyms
itonin;DIGITIN;igitonin;DIGITONIN;DigitoninGr;5% Digitonin;Digitonin, AR;DIGITONIN(RG);Digitonin USP;DIGITONINE AR
CBNumber
CB3331307
Molecular Formula
C56H92O29
Formula Weight
1229.31
MOL File
11024-24-1.mol
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DIGITONIN Property

Melting point:
230-240 °C (dec.)(lit.)
alpha 
D20 -54° (0.45 g in 15.8 ml methanol)
Boiling point:
788.4°C (rough estimate)
Density 
1.1421 (rough estimate)
refractive index 
-52 ° (C=1, EtOH)
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: 10 mg/mL at 95 °C hot, clear, colorless
pka
12.68±0.70(Predicted)
form 
White powder
color 
white
optical activity
[α]20/D 54°, c = 2.8 in methanol(lit.)
Merck 
14,3161
BRN 
78654
Stability:
Hygroscopic
InChIKey
FAAZZWIYYDUONB-JYIJKGCVSA-N
EPA Substance Registry System
Digitonin (11024-24-1)
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25
Safety Statements 
22-28-36/37-45
RIDADR 
UN 3462 6.1/PG 3
WGK Germany 
3
RTECS 
IH2050050
F 
3-10
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D141
Product name
Digitonin
Purity
Used as non-ionic detergent
Packaging
100mg
Price
$82
Updated
2024/03/01
Sigma-Aldrich
Product number
D141
Product name
Digitonin
Purity
Used as non-ionic detergent
Packaging
500mg
Price
$276
Updated
2024/03/01
TCI Chemical
Product number
D0540
Product name
Digitonin
Packaging
100mg
Price
$95
Updated
2024/03/01
Cayman Chemical
Product number
14952
Product name
Digitonin
Packaging
100mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
14952
Product name
Digitonin
Packaging
1g
Price
$435
Updated
2024/03/01
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DIGITONIN Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

enhances membrane permeability

Uses

Natural surfactant useful for receptor solubilization and cell permeabilization, e.g., blood platelets, hepatocytes, yeast or tumor cells

Uses

Digitonin has been used in a study to assess a procedure for isolating mitochondria from ascites tumor cells. It has also been used in a study to investigate its effect on the cytotoxicity of plant secondary metabolites in cancer cells. This mild nonionic detergent can be used to solubilize receptors and permeabilize cellular and nuclear membranes.

Uses

Clinical reagent (cholesterol determination).

General Description

Crystals or white powder.

Air & Water Reactions

Forms soapy aqueous suspension .

Reactivity Profile

DIGITONIN is incompatible with strong oxidizing agents and strong acids. (NTP, 1992

Fire Hazard

Flash point data for DIGITONIN are not available; however, DIGITONIN is probably combustible.

Safety Profile

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Mutation data reported. See also DIGITALIS. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

This digitoxin hexa-glycoside can be recrystallised from aqueous 85% EtOH or MeOH/diethyl ether. It is purified by preparative paper chromatography and developed with the upper phase of a mixture of nBuOH/H2O/AcOH (4:5:1), and the spot (RF 0.36) is eluted with 25% CCl3CO2H in CHCl3. It has also been purified by countercurrent distribution. It forms an ethanolate, and complexes with cholesterol and other sterols. [Ruhenstroth-Bauer & Breitenfeld Hoppe Seyler's Z Physiol Chem 302 111 1955, Grisvold J Am Pharm Assoc 23 664 1934, Beilstein 19 IV 1243.]

DIGITONIN Preparation Products And Raw materials

Raw materials

Preparation Products

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DIGITONIN Suppliers

Americas 1 Belgium 1 China 185 Czech Republic 1 Europe 4 France 2 Germany 8 India 23 Italy 1 Japan 6 Poland 1 Switzerland 5 United Kingdom 13 United States 45 Global 296
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
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View Lastest Price from DIGITONIN manufacturers

Henan Fengda Chemical Co., Ltd
Product
DIGITONIN 11024-24-1
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Career Henan Chemical Co
Product
DIGITONIN 11024-24-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1
Release date
2018-08-06

11024-24-1, DIGITONINRelated Search:

TRIPROPYLENE GLYCOL MONOMETHYL ETHER 2-Methylundecanal dimethylacetal 1,1-Dimethoxydecane LAURYL ALDEHYDE DIMETHYL ACETAL ISOVERTAL 411 L N-OCTYL-BETA-D-GLUCOPYRANOSIDE 2-Octyl-1-dodecanol DIGITONIN Tigogenin HEPTANAL-DIETHYLACETAL 5α-Cholestane CIS-1,2-CYCLOPENTANEDIOL KOHINOOL Dihydrocholesterol (25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL TRIGLYCEROL 3-BUTOXY-PROPIONALDEHYDE DIETHYL ACETAL ISOGRISAL 7 C

  • 25R,5ALPHA-SPIROSTAN-2ALPHA,3BETA,15BETA-TRIOL 3BETA-O-BETA-D-GALACTOPYRANOSYL-(1->3)-O-BETA-D-GALACTYOPYRANOSYL-(1->2)-O-BETA-D-[3-O-BETA-D-XYLOPYRANOSYL]-(1->4)-O-BETA-D-GALACTOPYRANOSIDE
  • DIGITONIN CRYSTALLINE
  • Digitonin, High Purity
  • DIGITONIN (DIGITIN) HIGH PURITY RECEPTOR SOLUBILIZING
  • DigitoninGr
  • Digitonin, AR
  • DIGITONIN, USED AS NON-IONIC DETERGE
  • beta.-D-Galactopyranoside, (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1?3)-O-.beta.-D-galactopyranosyl-(1?2)-O-.beta.-D-xylopyranosyl-(1?3)-O-.beta.-D-glucopyranosyl-(1?4)-
  • (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1 .beta.-D-Galactopyranoside
  • DIGITONIN TECH
  • DIGITONIN,CRYSTAL,REAGENT
  • DIGITONIN(RG)
  • (1→3)]-O-β-D-glucopyranosyl-(1→4)- β-D-
  • (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-ylO-.beta.-D-glucopyranosyl-(1.beta.-D-Galactopyranoside
  • beta-d-galactopyranoside,(2alpha,3beta,5alpha,15beta,25theta)-2,15-dihyd
  • osyl-(1.fwdarw.2)-o-[beta-d-xylopyranosyl-(1.fwdarw.3)]-o-beta-d-glucopyranos
  • roxyspirostan-3-ylo-beta-d-glucopyranosyl-(1.fwdarw.3)-o-beta-d-galactopyran
  • yl-(1.fwdarw.4)-
  • Digitonin ,50%
  • 2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl-O-β-D-glucopyranosyl-1β-D-Galactopyranoside
  • DIGITIN
  • DIGITONIN
  • DIGITONIN, ALCOHOL-SOLUBLE
  • DIGITONIN WATER SOLUBLE
  • Digitogenin,3-[O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl-
  • galactopyranoside]
  • Digitonin, approx. 50% (TLC)
  • [(25R)-2α,15β-Dihydroxy-5α-spirostan-3β-yl]4-O-[2-O-[3-O-(β-D-glucopyranosyl)-β-D-galactopyranosyl]-3-O-(β-D-xylopyranosyl)-β-D-glucopyranosyl]-β-D-galactopyranoside
  • Digitonin, approx. 50% (TLC) 500MG
  • Digitonin, approx. 50% (TLC) 5GR
  • DIGITONINANALYTICAL GRADE
  • DIGITONIN WATER SOLUBLERESEARCH GRADE
  • Digitonin,Digitin
  • Digitonin, approx. 50%, water soluble
  • 5% Digitonin
  • Digitonin USP
  • itonin
  • β-D-Galactopyranoside, (2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-
  • Digitonin (Digitin) extrapure, 50%
  • 3-Benzoxazole-6-carboxylic acid
  • igitonin
  • Digitonin (8CI)
  • Digitonin 99% AR
  • DIGITONINE AR
  • 11024-24-1
  • C56H92O29
  • C56H92O28
  • Sterols
  • Lipids
  • Non-Ionic
  • Detergents
  • Conjugates
  • Biochemicals and Reagents
  • BioChemical
  • Surfactants (for Biochemistry)
  • Sugars
  • Nonionic Surfactants (for Biochemistry)
  • Glycosides