DIGITONIN
- Product Name
- DIGITONIN
- CAS No.
- 11024-24-1
- Chemical Name
- DIGITONIN
- Synonyms
- itonin;DIGITIN;igitonin;DIGITONIN;DigitoninGr;5% Digitonin;Digitonin, AR;DIGITONIN(RG);Digitonin USP;DIGITONINE AR
- CBNumber
- CB3331307
- Molecular Formula
- C56H92O29
- Formula Weight
- 1229.31
- MOL File
- 11024-24-1.mol
DIGITONIN Property
- Melting point:
- 230-240 °C (dec.)(lit.)
- alpha
- D20 -54° (0.45 g in 15.8 ml methanol)
- Boiling point:
- 788.4°C (rough estimate)
- Density
- 1.1421 (rough estimate)
- refractive index
- -52 ° (C=1, EtOH)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- H2O: 10 mg/mL at 95 °C hot, clear, colorless
- pka
- 12.68±0.70(Predicted)
- form
- White powder
- color
- white
- optical activity
- [α]20/D 54°, c = 2.8 in methanol(lit.)
- Merck
- 14,3161
- BRN
- 78654
- Stability:
- Hygroscopic
- InChIKey
- FAAZZWIYYDUONB-JYIJKGCVSA-N
- EPA Substance Registry System
- Digitonin (11024-24-1)
Safety
- Hazard Codes
- T
- Risk Statements
- 23/24/25
- Safety Statements
- 22-28-36/37-45
- RIDADR
- UN 3462 6.1/PG 3
- WGK Germany
- 3
- RTECS
- IH2050050
- F
- 3-10
- HazardClass
- 6.1(a)
- PackingGroup
- II
- HS Code
- 29389090
N-Bromosuccinimide Price
- Product number
- D141
- Product name
- Digitonin
- Purity
- Used as non-ionic detergent
- Packaging
- 100mg
- Price
- $82
- Updated
- 2024/03/01
- Product number
- D141
- Product name
- Digitonin
- Purity
- Used as non-ionic detergent
- Packaging
- 500mg
- Price
- $276
- Updated
- 2024/03/01
- Product number
- D0540
- Product name
- Digitonin
- Packaging
- 100mg
- Price
- $95
- Updated
- 2024/03/01
- Product number
- 14952
- Product name
- Digitonin
- Packaging
- 100mg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 14952
- Product name
- Digitonin
- Packaging
- 1g
- Price
- $435
- Updated
- 2024/03/01
DIGITONIN Chemical Properties,Usage,Production
Chemical Properties
white crystalline powder
Uses
enhances membrane permeability
Uses
Natural surfactant useful for receptor solubilization and cell permeabilization, e.g., blood platelets, hepatocytes, yeast or tumor cells
Uses
Digitonin has been used in a study to assess a procedure for isolating mitochondria from ascites tumor cells. It has also been used in a study to investigate its effect on the cytotoxicity of plant secondary metabolites in cancer cells. This mild nonionic detergent can be used to solubilize receptors and permeabilize cellular and nuclear membranes.
Uses
Clinical reagent (cholesterol determination).
General Description
Crystals or white powder.
Air & Water Reactions
Forms soapy aqueous suspension .
Reactivity Profile
DIGITONIN is incompatible with strong oxidizing agents and strong acids. (NTP, 1992
Fire Hazard
Flash point data for DIGITONIN are not available; however, DIGITONIN is probably combustible.
Safety Profile
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Mutation data reported. See also DIGITALIS. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods
This digitoxin hexa-glycoside can be recrystallised from aqueous 85% EtOH or MeOH/diethyl ether. It is purified by preparative paper chromatography and developed with the upper phase of a mixture of nBuOH/H2O/AcOH (4:5:1), and the spot (RF 0.36) is eluted with 25% CCl3CO2H in CHCl3. It has also been purified by countercurrent distribution. It forms an ethanolate, and complexes with cholesterol and other sterols. [Ruhenstroth-Bauer & Breitenfeld Hoppe Seyler's Z Physiol Chem 302 111 1955, Grisvold J Am Pharm Assoc 23 664 1934, Beilstein 19 IV 1243.]
DIGITONIN Preparation Products And Raw materials
Raw materials
Preparation Products
DIGITONIN Suppliers
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- Switzerland
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View Lastest Price from DIGITONIN manufacturers
- Product
- DIGITONIN 11024-24-1
- Price
- US $8.00-0.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09
- Product
- DIGITONIN 11024-24-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1
- Release date
- 2018-08-06