ChemicalBook > CAS DataBase List > Tigogenin
Tigogenin
- Product Name
- Tigogenin
- CAS No.
- 77-60-1
- Chemical Name
- Tigogenin
- Synonyms
- Nsc93754;TIGOGENIN;Ticogenin;Sisalagenin;TIGOGENIN90%;Tigogenin-RM;Sisal saponin;Spirostan-3-ol;SMILAGENIN(RG);Trigonegenin B
- CBNumber
- CB1669512
- Molecular Formula
- C27H44O3
- Formula Weight
- 416.64
- MOL File
- 77-60-1.mol
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Tigogenin Property
- Melting point:
- 202-204°C
- alpha
- -68 º (c=0.8g/100ml, CHCl3)
- Boiling point:
- 474.91°C (rough estimate)
- Density
- 1.0362 (rough estimate)
- refractive index
- 1.4700 (estimate)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly)
- pka
- 15.14±0.70(Predicted)
- form
- Solid
- color
- Off-White
- optical activity
- -67.218 (c 1, CHCl3)
- CAS DataBase Reference
- 77-60-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Tigogenin(77-60-1)
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Safety
- RTECS
- WH1443500
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- PHL83916
- Product name
- Tigogenin
- Purity
- phyproof? Reference Substance
- Packaging
- 10MG
- Price
- $457
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 30137
- Product name
- Tigogenin
- Packaging
- 10mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 30137
- Product name
- Tigogenin
- Packaging
- 250mg
- Price
- $745
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 30137
- Product name
- Tigogenin
- Packaging
- 50mg
- Price
- $193
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 30137
- Product name
- Tigogenin
- Packaging
- 100mg
- Price
- $341
- Updated
- 2024/03/01
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Tigogenin Chemical Properties,Usage,Production
Description
Tigogenin is a steroidal sapogenin that has been found in A. sisalana and has diverse biological activities. It increases the proliferation rate of, as well as mRNA levels of genes encoding the osteoblastic differentiation markers Cbfa1, collagen type I, and osteocalcin in, mouse bone marrow stromal cells (BMSCs) in a concentration-dependent manner. It also increases matrix calcium deposition in BMSCs when used at concentrations of 30 and 90 μM. Tigogenin is active against the fungus A. fumigatus (MIC50 = 16 μg/ml). It inhibits carrageenan-induced paw edema in rats when administered at a dose of 4.2 μg/kg.
Chemical Properties
mp 196-208C° LOD ≤0.5%
Uses
Tigogenin is a saponin structurally similar to Diosgenin (D484700) and acts as a natural plant steroid which induces apoptosis in rheumatoid arthritic fibroblast-like synoviocytes.
Definition
ChEBI: Tigogenin is a widely used steroidal sapogenin isolated from several plant species and used for synthesizing steroid drugs. It has a role as a gout suppressant and a plant metabolite.
Tigogenin Preparation Products And Raw materials
Raw materials
Preparation Products
Androst-3-ol-17-one 3-p-toluenesulfonate
3-Acetyloxy-16-methylpregna-9(11),16-dien-20-one
3-Acetyloxypregn-16-en-20-one
16-Methylpregnane-17,21-diol-3,20-dione 21-acetate
17-alpha-hydroxy-16-alpha-methyl-3,20-dioxopregna- 1,4-dien-21-yl acetate
Oxymetholone
16,17-Epoxy-3-hydroxy-16-methyl-pregn-9(11)-ene-20-one-3-acetate
3beta-hydroxy-5alpha-pregna-9(11),16-dien-20-one 3-acetate
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Tigogenin Suppliers
- Tel
- 021-021-59178156 17002132182
- 3146474380@qq.com
- Country
- China
- ProdList
- 11603
- Advantage
- 58
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15839
- Advantage
- 69
- Tel
- +86-21-20908456
- Fax
- 021-58180499
- sales@BioChemBest.com
- Country
- China
- ProdList
- 6005
- Advantage
- 61
- Tel
- 15527768850
- 1791901229@qq.com
- Country
- China
- ProdList
- 8843
- Advantage
- 52
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 0086-21-58956006
- Fax
- 0086-21-58956100
- Country
- China
- ProdList
- 7811
- Advantage
- 57
- Tel
- 021-51613915-820 13611835272
- Fax
- 021 51613951
- mmwang@sunwaypharm.cn
- Country
- China
- ProdList
- 9734
- Advantage
- 57
- Tel
- 0411-62910999 13889544652
- meilunui@163.com
- Country
- China
- ProdList
- 4727
- Advantage
- 58
- Tel
- 0871-65217109 13211707573;
- Fax
- 0871-65215563
- y.liu@mail.biobiopha.com
- Country
- China
- ProdList
- 5653
- Advantage
- 65
- Tel
- 021-61312847 13636370518
- Fax
- 021-55068248
- shyysw007@163.com
- Country
- China
- ProdList
- 4940
- Advantage
- 60
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View Lastest Price from Tigogenin manufacturers
Shanghai Standard Technology Co., Ltd.
- Product
- Tigogenin 77-60-1
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-11-22
Honest Joy Holdings Limited
- Product
- Tigogenin 77-60-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.9%
- Supply Ability
- 100 tons
- Release date
- 2022-02-18
Longyan Tianhua Biological Technology Co., Ltd
- Product
- Tigogenin 77-60-1
- Price
- US $30.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 999
- Release date
- 2020-10-29
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