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Ginseng extract

Product Name
Ginseng extract
CAS No.
90045-38-8
Chemical Name
Ginseng extract
Synonyms
GINSENG;PANAX GINSENG ROOT EXTRACT;Ginseng oil;TOTAL GINSENOSIDES;panax quinquefolius root extract;GINSENG ROOT;Ginsenoside UV;Ginseng 100%;GINSENG, RED;GINSENG KOREAN
CBNumber
CB7736407
Molecular Formula
C15H24N2O
Formula Weight
248.37
MOL File
Mol file
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Ginseng extract Property

Odor
at 100.00 %. linalool citrus fresh
Odor Type
citrus
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Safety

HS Code 
2938900000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1291683
Product name
Powdered American Ginseng Extract
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
1.5G
Price
$1130
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
BIO0000391
Product name
GINSENG
Purity
95.00%
Packaging
5MG
Price
$497.28
Updated
2021/12/16
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Ginseng extract Chemical Properties,Usage,Production

Occurrence

Ginseng is now found throughout the world. Panax quinquefolius is native to North America; Panax ginseng is native to the Far East.

Uses

ginseng extract (Panax sp.) is considered tonic and nourishing because of its vitamin and hormone content. It seems to aid in diminishing wrinkles and helps dry skin. It is also said to promote skin elasticity, perhaps by stimulating sterol and protein production. other claims include skin rejuvenating, oxygenating, and stimulating properties. Folkloric remedies cite use for boils, bruises, sores, and swellings. This root’s active components are called ginsenosides and these are said to be responsible for revitalizing and reactivating epidermal cells. other important constituents include saponins, mucin, and vitamin B. The extract comes from the root. ginseng has been associated with many allergic skin reactions.

Indications

Panax ginseng describes the root from two species of plants, Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolius), popularly used for improving stamina and providing a sense of well-being. The terms red and white ginseng refer to how the root is processed, not the species of origin. Red ginseng roots are steam-cured prior to drying, while white ginseng is bleached and dried. Panax ginsengs contain triterpenoid saponins called ginsenosides (also called panaxosides), of which up to 18 types are recognized as having differing and sometimes opposing pharmacological properties.
Siberian ginseng (Eleutherococcus senticosus) should not be confused with Panax ginseng.Although it belongs to the same plant family (Araliaceae), it is a much larger, more abundant, and consequently less expensive plant. Like Panax ginseng, however, it is used as a tonic and adaptogen, a nonmedical term meaning that it helps the body adapt to stress in a variety of ways. Siberian ginseng does contain saponins (eleutherosides) but no ginsenosides. To date, in spite of its popularity, there is little conclusive evidence of clinical efficacy.

General Description

Major components are named the ginsenosides. The chemical constituents of ginseng are called ginsenosides or panaxosides. A total of 12 of these have been isolated but are present in such small quantities that purification is difficult. Sterols, flavonoids, proteins, and vitamins (B1, B2, B12, pantothenic acid, niacin, and biotin) are also components with pharmacological activity. The chemistry of ginseng gives a good example of how different compounds in one herb can have opposing pharmacological effects. Ginsenoside Rb-1 acts as a CNS depressant, anticonvulsant, analgesic, and antipsychotic, prevents stress ulcers, and accelerates glycolysis and nuclear RNA synthesis. Ginsenoside Rg-1 stimulates the CNS, combats fatigue, is hypertensive, and aggravates stress ulcers.
Additionally, ginsenosides Rg and Rg-1 enhance cardiac performance, whereas Rb depresses that function. Some of the other ginsenosides display antiarrhythmic activity similar to that of the calcium channel blocker verapamil and amiodarone. Ginseng is popularly believed to enhance concentration, stamina, alertness, and the ability to do work. Longer-term use in elderly patients is claimed to enhance “well-being.”.

Mechanism of action

Ginsenosides are thought to be the active principles in Panax ginseng root. The various subtypes can have opposing pharmacological actions: Rg1 stimulates the central nervous system (CNS) and elevates blood pressure, while Rb1 does just the opposite. Somehow these multiple ginsenoside constituents are thought to act in concert to provide increased stamina. In addition, these compounds have antiplatelet aggregation effects and antioxidant properties, and they may stimulate the immune system.

Anticancer Research

Ginseng can refer to either white or red ginseng, and herbal preparations varyaccording to the type. In European herbal medicine, ginseng is powdered into300 mg/capsule, with 2–3 capsule/day dosage (Lust 2014). For ginseng in dryextract, 15 ml of oral liquid is given once daily. Each 15 ml of oral liquid contains140 mg of dry extract (Kapoor 2000). American ginseng is also listed as an ingredientin some soft drinks, and its oil and extracts are used in soap and cosmetics(Gupta et al. 2004). There is a little evidence in terms of clinical research to supportginseng treating breast cancer (Shin et al. 2000). However, research conducted inChina suggests that patients treated with any form of ginseng maintained betterpsychological condition. Thus, it might be more appropriate to say it has benefits interms of supporting and minimising damage from the cancer drug tamoxifen intreatment (Cui et al. 2006).

Clinical Use

Despite the long popularity of ginseng and its evident mild stimulatory effect, there is less conclusive evidence for its clinical effectiveness than for many of the other herbs discussed in this chapter. In regard to improving cognitive function, most studies have failed to prove a consistent benefit. A recent investigation of ginseng’s effect on physical stamina found that an 8-week course of therapy failed to improve aerobic work capacity. Ginseng has been studied as a diabetic agent, with reduced hemoglobin A1c levels and improved glucose control being documented in a small trial. Although there is some intriguing work with ginseng as a cancer preventive, there is not enough evidence to suggest its clinical use at this time.

Side effects

Ginseng is generally considered safe for nonpregnant healthy adults; however, at sufficient doses, ginseng may elevate blood pressure and cause insomnia, palpitations, nervousness, and tremor in susceptible individuals. These effects are increased if caffeine or other stimulants are taken concurrently. Both Panax and Siberian ginsengs should definitely be avoided in any patient with poorly controlled hypertension. Dizziness, headache, diarrhea, and nausea have also been reported. A controversial ginseng abuse syndrome consisting of tremor, elevated blood pressure, insomnia, and anxiety may also occur.
Diabetic patients have had hypoglycemia on ginseng, so sugars must be monitored, and insulin or other hypoglycemic medication dosages may have to be reduced. The use of ginseng with anticoagulants (e.g., warfarin) and antiplatelet drugs is to be avoided because of the theoretical risk of increased bleeding. Also, coadministration of ginseng with digoxin and MAOIs should be avoided.

Ginseng extract Preparation Products And Raw materials

Raw materials

Preparation Products

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Ginseng extract Suppliers

Shaanxi Pioneer Biotech CO., Ltd
Tel
029-86107037-8019 15332321378
Email
sales@pioneerbiotech.com
Country
China
ProdList
368
Advantage
58
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
Wuhan Fortuna Chemical Co., Ltd
Tel
027-027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2893
Advantage
58
Shanghai Winherb Medical Technology Co., Ltd.
Tel
400-186-5138 13341702378
Fax
QQ:190129269
Email
winherb@126.com
Country
China
ProdList
1009
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7892
Advantage
56
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
13358
Advantage
58
Shaanxi Pioneer Biotech Co., Ltd.
Tel
13720616393;029-84385017-8003 13720616393
Fax
029-84385017
Email
sales@pioneerbiotech.com
Country
China
ProdList
1065
Advantage
56
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
551-65418679 15837135945
Fax
0551-65418697
Email
info@tnjchem.com
Country
China
ProdList
1889
Advantage
62
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29797
Advantage
68
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View Lastest Price from Ginseng extract manufacturers

Hebei Dangtong Import and export Co LTD
Product
Ginseng extract 90045-38-8
Price
US $110.00-100.00/kg
Min. Order
100kg
Purity
99.99%
Supply Ability
100Tons
Release date
2023-03-03
Sinoway Industrial co., ltd.
Product
Ginseng Extract 90045-38-8
Price
US $125.00-35.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
1~30%HPLC; 80-90%UV
Supply Ability
20 tons
Release date
2023-12-29
Changsha Staherb Natural Ingredients Co., Ltd.
Product
ginseng extract 90045-38-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
10:1
Supply Ability
1000kg
Release date
2022-10-09

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