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HECOGENIN ACETATE

Product Name
HECOGENIN ACETATE
CAS No.
915-35-5
Chemical Name
HECOGENIN ACETATE
Synonyms
HECOGENIN ACETATE;HECOGENIN ALCOHOL;HecogeninAcetate>(-)-HECOGENIN ACETATE, TECH., 90%;(25R)-3β-Acetoxy-5α-spirostane-12-one;Hecogenin acetate,()-Hecogenin acetate;(25R)-3β-Acetyloxy-5α-spirostan-12-one;(22R,25R)-3β-Acetoxy-5α-spirostane-12-one;12-oxo-5-alpha-spirostan-3-beta-yl acetate;(25R)-3β-Hydroxy-5α-spirostane-12-one=acetate
CBNumber
CB6442059
Molecular Formula
C29H44O5
Formula Weight
472.66
MOL File
915-35-5.mol
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HECOGENIN ACETATE Property

Melting point:
246-248 °C (dec.)(lit.)
Boiling point:
95-140 °C
Density 
1.15±0.1 g/cm3(Predicted)
refractive index 
-4 ° (C=1, Dioxane)
storage temp. 
Refrigerator
solubility 
Chloroform (Sparingly), Dioxane (Sparingly, Heated), Ethyl Acetate (Slightly, Heated)
form 
Solid
color 
White
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2937.29.9095
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H4274
Product name
Hecogenin acetate
Purity
≥90%
Packaging
25g
Price
$664
Updated
2023/01/07
TCI Chemical
Product number
H0537
Product name
Hecogenin Acetate
Purity
>90.0%(GC)
Packaging
1g
Price
$62
Updated
2024/03/01
TCI Chemical
Product number
H0537
Product name
Hecogenin Acetate
Purity
>90.0%(GC)
Packaging
5g
Price
$160
Updated
2024/03/01
Cayman Chemical
Product number
25977
Product name
Hecogenin Acetate
Purity
≥98%
Packaging
1g
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
25977
Product name
Hecogenin Acetate
Purity
≥98%
Packaging
5g
Price
$166
Updated
2024/03/01
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HECOGENIN ACETATE Chemical Properties,Usage,Production

Description

Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin that has anthelmintic and antinociceptive properties. It reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC50 = 0.49 mg/ml). Hecogenin acetate (5, 10, or 20 mg/kg, i.p.) inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-α, dopamine , and prostaglandin E2 (PGE2; ) in mice. It also increases latency to tail withdrawal in the tail flick test and has no effect on motor performance in the rotarod test in mice when administered at a dose of 40 mg/kg.

Uses

Hecogenin Acetate, is a derivative of Hecogenin (H129945), which is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties.

Definition

ChEBI: HECOGENIN ACETATE is a triterpenoid.

Purification Methods

Crystallise the acetate from MeOH. [Beilstein 19 IV 2583.]

HECOGENIN ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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HECOGENIN ACETATE Suppliers

Americas 1 China 35 Europe 1 Germany 2 India 2 Japan 2 Switzerland 1 United Kingdom 4 United States 23 Global 71
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23680
Advantage
75
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8073
Advantage
58

915-35-5, HECOGENIN ACETATERelated Search:

2,2-DIMETHYL-3-HEXANONE HEPTANAL DIMETHYL ACETAL LAURYL ALDEHYDE DIMETHYL ACETAL HECOGENIN ACETATE 3-METHYLCYCLOHEXANONE 8-PENTADECANONE ISOVERTAL 411 L 7-HEXADECANONE 2-methoxytetrahydrofuran 2-ETHOXYTETRAHYDROFURAN PROPIONALDEHYDE DIETHYL ACETAL 2-METHYL-3-NONANONE N-HEPTADECYLCYCLOHEXANE 7-PENTADECANONE 1,1-Dimethoxyoctane Saponin Hecogenin ACETIC ACID 2-NONYL ESTER

  • 25R,5ALPHA-SPIROSTAN-3BETA-OL-12-ONE 3-ACETATE
  • 5-ALPHA, 20-ALPHA, 22-ALPHA, 25D-SPIROSTAN-3-BETA-OL-12-ONE ACETATE
  • HECOGENIN ACETATE
  • 12-oxo-5-alpha-spirostan-3-beta-yl acetate
  • (-)-HECOGENIN ACETATE, TECH., 90%
  • HECOGENIN ALCOHOL
  • (22R,25R)-3β-Acetoxy-5α-spirostane-12-one
  • (25R)-3β-Acetoxy-5α-spirostane-12-one
  • (25R)-3β-Acetyloxy-5α-spirostan-12-one
  • (25R)-3β-Hydroxy-5α-spirostane-12-one=acetate
  • Hecogenin acetate,()-Hecogenin acetate
  • HecogeninAcetate&gt
  • Spirostan-12-one, 3-(acetyloxy)-, (3β,5α,25R)-
  • 5α, 20α, 22α, 25D-SPIROSTAN-3β-OL-12-ONE ACETATE
  • 915-35-5
  • C29H44O5
  • Steroids
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  • Pharmaceutical Intermediates
  • Biochemistry
  • Steroids
  • Steroids (Others)