HECOGENIN ACETATE
- Product Name
- HECOGENIN ACETATE
- CAS No.
- 915-35-5
- Chemical Name
- HECOGENIN ACETATE
- Synonyms
- HECOGENIN ACETATE;HECOGENIN ALCOHOL;HecogeninAcetate>(-)-HECOGENIN ACETATE, TECH., 90%;(25R)-3β-Acetoxy-5α-spirostane-12-one;Hecogenin acetate,()-Hecogenin acetate;(25R)-3β-Acetyloxy-5α-spirostan-12-one;(22R,25R)-3β-Acetoxy-5α-spirostane-12-one;12-oxo-5-alpha-spirostan-3-beta-yl acetate;(25R)-3β-Hydroxy-5α-spirostane-12-one=acetate
- CBNumber
- CB6442059
- Molecular Formula
- C29H44O5
- Formula Weight
- 472.66
- MOL File
- 915-35-5.mol
HECOGENIN ACETATE Property
- Melting point:
- 246-248 °C (dec.)(lit.)
- Boiling point:
- 95-140 °C
- Density
- 1.15±0.1 g/cm3(Predicted)
- refractive index
- -4 ° (C=1, Dioxane)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Sparingly), Dioxane (Sparingly, Heated), Ethyl Acetate (Slightly, Heated)
- form
- Solid
- color
- White
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 2937.29.9095
N-Bromosuccinimide Price
- Product number
- H4274
- Product name
- Hecogenin acetate
- Purity
- ≥90%
- Packaging
- 25g
- Price
- $664
- Updated
- 2023/01/07
- Product number
- H0537
- Product name
- Hecogenin Acetate
- Purity
- >90.0%(GC)
- Packaging
- 1g
- Price
- $62
- Updated
- 2024/03/01
- Product number
- H0537
- Product name
- Hecogenin Acetate
- Purity
- >90.0%(GC)
- Packaging
- 5g
- Price
- $160
- Updated
- 2024/03/01
- Product number
- 25977
- Product name
- Hecogenin Acetate
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 25977
- Product name
- Hecogenin Acetate
- Purity
- ≥98%
- Packaging
- 5g
- Price
- $166
- Updated
- 2024/03/01
HECOGENIN ACETATE Chemical Properties,Usage,Production
Description
Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin that has anthelmintic and antinociceptive properties. It reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC50 = 0.49 mg/ml). Hecogenin acetate (5, 10, or 20 mg/kg, i.p.) inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-α, dopamine , and prostaglandin E2 (PGE2; ) in mice. It also increases latency to tail withdrawal in the tail flick test and has no effect on motor performance in the rotarod test in mice when administered at a dose of 40 mg/kg.
Uses
Hecogenin Acetate, is a derivative of Hecogenin (H129945), which is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties.
Definition
ChEBI: HECOGENIN ACETATE is a triterpenoid.
Purification Methods
Crystallise the acetate from MeOH. [Beilstein 19 IV 2583.]