ChemicalBook > CAS DataBase List > 1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
- Product Name
- 1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
- CAS No.
- 174689-39-5
- Chemical Name
- 1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
- Synonyms
- SR 59230A;SR59230AHCl;SR 59230A HYDROCHLORIDE;SR 59230A >=98% (HPLC), powder;(2S)-1-(2-ethylphenoxy)-3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino}propan-2-ol;3-(2-ETHYLPHENOXY)-1-((1S)-1,2,3,4-TETRA-HYDRONAPHTH-1-YLAMINO)-(2S)-2-PROPANOL OXALATE;(S)-1-(2-Ethylphenoxy)-3-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)amino)propan-2-ol oxalate;3-(2-Ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphth-1-yl]amino]-(2S)-2-propanol oxalate salt;1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE;hyperthermia,adrenoceptor,Adrenergic Receptor,adrenergic,Beta Receptor,inhibit,hypothermia,receptor,Inhibitor,SR59230A,SR-59230A
- CBNumber
- CB3331761
- Molecular Formula
- C23H29NO6
- Formula Weight
- 415.49
- MOL File
- 174689-39-5.mol
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1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Property
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO: >10mg/mL
- form
- powder
- color
- white
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Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- S8688
- Product name
- SR 59230A
- Purity
- ≥98% (HPLC), powder
- Packaging
- 5mg
- Price
- $165
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- S8688
- Product name
- SR 59230A
- Purity
- ≥98% (HPLC), powder
- Packaging
- 25mg
- Price
- $228.4
- Updated
- 2024/03/01
Tocris
- Product number
- 1511
- Product name
- SR59230Ahydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $220
- Updated
- 2021/12/16
Tocris
- Product number
- 1511
- Product name
- SR59230Ahydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $926
- Updated
- 2021/12/16
Usbiological
- Product number
- 256751
- Product name
- SR 59230A hydrochloride
- Packaging
- 10mg
- Price
- $466
- Updated
- 2021/12/16
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1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
SR 59230A was used in the identification of β-adrenoceptors in rat aorta.3 It was tested as a potential therapeutic agent in improving cardiac function in rat model of heart failure.4
Hazard
A poison.
Biological Activity
Potent and selective β 3 adrenoceptor antagonist (IC 50 values are 40, 408 and 648 nM for β 3 , β 1 and β 2 receptors respectively). Orally active in vivo . Also available as part of the β -Adrenoceptor Antagonist Tocriset™ .
Biochem/physiol Actions
SR 59230A is a β3-adrenoceptor antagonist. It has high affinity for the β3 adrenoceptors occurring in human gut that affect the function of human colonic circular smooth muscle.1 It is reported that SR 59230A inhibits the Kir2.1-2.3 cardiac potassium channels.2
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77
174689-39-5, 1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDERelated Search:
(S)-N-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE
(S)--1-AMINOTETRALINE HCL
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
(S)-(-)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL