ChemicalBook > CAS DataBase List > Phlorizin dihydrate

Phlorizin dihydrate

Product Name
Phlorizin dihydrate
CAS No.
7061-54-3
Chemical Name
Phlorizin dihydrate
Synonyms
PHLORIDZIN;PHLORIDZIN(RG);TIMTEC-BB SBB005924;Phlorizin dihydrate;Phloridzin dihydrate 99%;phloridzin from apple wood;PHLORETIN-2'-BETA-D-GLUCOSIDE;Phlorizin dihydrate USP/EP/BP;Phloretin 2'-b-D-glucopyranoside;Phlorizin dihydrate, 10 mM in DMSO
CBNumber
CB3331802
Molecular Formula
C21H26O11
Formula Weight
454.43
MOL File
7061-54-3.mol
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Phlorizin dihydrate Property

Melting point:
113-114 °C(lit.)
alpha 
-52 º (c=3, EtOH)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Solid
color 
White to off-white
optical activity
[α]20/D 52°, c = 3 in ethanol
biological source
apple wood
BRN 
66621
CAS DataBase Reference
7061-54-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
UC2080000
3-10-23
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
274313
Product name
Phloridzin dihydrate
Purity
99%
Packaging
1g
Price
$166
Updated
2024/03/01
Sigma-Aldrich
Product number
274313
Product name
Phloridzin dihydrate
Purity
97%
Packaging
5g
Price
$477
Updated
2024/03/01
Sigma-Aldrich
Product number
P3449
Product name
Phloridzin dihydrate
Purity
from apple wood, ≥99% (HPLC)
Packaging
100mg
Price
$58.2
Updated
2024/03/01
Sigma-Aldrich
Product number
P3449
Product name
Phloridzin dihydrate
Purity
from apple wood, ≥99% (HPLC)
Packaging
500mg
Price
$76.2
Updated
2024/03/01
Sigma-Aldrich
Product number
P3449
Product name
Phloridzin dihydrate
Purity
from apple wood, ≥99% (HPLC)
Packaging
1g
Price
$142
Updated
2024/03/01
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Phlorizin dihydrate Chemical Properties,Usage,Production

Uses

Phloridzin dihydrate has been used as:

  • a Na+-glucose cotransport inhibitor to test its effect in lowering blood glucose
  • a hexose carrier inhibitor to prevent glucose derivative 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) uptake in sycamore cells
  • a non-specific sodium-glucose co-transporter 2 (SGLT2) inhibitor in embryonic cardiomyocyte cell line H9C2 to investigate its protective effect on Dox-induced cytotoxicity

Biochem/physiol Actions

Phloridzin is a glycoside present in the leaves and bark of apple. It is also present in peel and pulp of the apple fruit. Phloridzin belongs to the dihydrochalcones class of compounds. Lactase catabolizes phloridzin to phloretin and glucose in small intestine epithelial cells. Phloridzin is an antidiabetic agent and is equally bioavailable as phloretin.

target

NO | PGE | NOS | COX

Phlorizin dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Phlorizin dihydrate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Phlorizin dihydrate 7061-54-3
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-12-06
Career Henan Chemical Co
Product
Phlorizin dihydrate 7061-54-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10 tons/month
Release date
2020-01-08

7061-54-3, Phlorizin dihydrateRelated Search:


  • Phlorizin dihydrate 1-[2-(beta-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate
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  • 2'-O-GLUCOSYL-4',6',4-TRIHYDROXYDIHYDROCHALCONE
  • 1-[2-(beta-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate
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  • Phloridzin dihydrate,1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, Phloretin 2′-β-D-glucopyranoside, Phloretin 2′-β-D-glucoside, Phlorizin dihydrate
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