Phlorizin dihydrate
- Product Name
- Phlorizin dihydrate
- CAS No.
- 7061-54-3
- Chemical Name
- Phlorizin dihydrate
- Synonyms
- PHLORIDZIN;PHLORIDZIN(RG);TIMTEC-BB SBB005924;Phlorizin dihydrate;Phloridzin dihydrate 99%;phloridzin from apple wood;PHLORETIN-2'-BETA-D-GLUCOSIDE;Phlorizin dihydrate USP/EP/BP;Phloretin 2'-b-D-glucopyranoside;Phlorizin dihydrate, 10 mM in DMSO
- CBNumber
- CB3331802
- Molecular Formula
- C21H26O11
- Formula Weight
- 454.43
- MOL File
- 7061-54-3.mol
Phlorizin dihydrate Property
- Melting point:
- 113-114 °C(lit.)
- alpha
- -52 º (c=3, EtOH)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Solid
- color
- White to off-white
- optical activity
- [α]20/D 52°, c = 3 in ethanol
- biological source
- apple wood
- BRN
- 66621
- CAS DataBase Reference
- 7061-54-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 274313
- Product name
- Phloridzin dihydrate
- Purity
- 99%
- Packaging
- 1g
- Price
- $166
- Updated
- 2024/03/01
- Product number
- 274313
- Product name
- Phloridzin dihydrate
- Purity
- 97%
- Packaging
- 5g
- Price
- $477
- Updated
- 2024/03/01
- Product number
- P3449
- Product name
- Phloridzin dihydrate
- Purity
- from apple wood, ≥99% (HPLC)
- Packaging
- 100mg
- Price
- $58.2
- Updated
- 2024/03/01
- Product number
- P3449
- Product name
- Phloridzin dihydrate
- Purity
- from apple wood, ≥99% (HPLC)
- Packaging
- 500mg
- Price
- $76.2
- Updated
- 2024/03/01
- Product number
- P3449
- Product name
- Phloridzin dihydrate
- Purity
- from apple wood, ≥99% (HPLC)
- Packaging
- 1g
- Price
- $142
- Updated
- 2024/03/01
Phlorizin dihydrate Chemical Properties,Usage,Production
Uses
Phloridzin dihydrate has been used as:
- a Na+-glucose cotransport inhibitor to test its effect in lowering blood glucose
- a hexose carrier inhibitor to prevent glucose derivative 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) uptake in sycamore cells
- a non-specific sodium-glucose co-transporter 2 (SGLT2) inhibitor in embryonic cardiomyocyte cell line H9C2 to investigate its protective effect on Dox-induced cytotoxicity
Biochem/physiol Actions
Phloridzin is a glycoside present in the leaves and bark of apple. It is also present in peel and pulp of the apple fruit. Phloridzin belongs to the dihydrochalcones class of compounds. Lactase catabolizes phloridzin to phloretin and glucose in small intestine epithelial cells. Phloridzin is an antidiabetic agent and is equally bioavailable as phloretin.
target
NO | PGE | NOS | COX
Phlorizin dihydrate Preparation Products And Raw materials
Raw materials
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View Lastest Price from Phlorizin dihydrate manufacturers
- Product
- Phlorizin dihydrate 7061-54-3
- Price
- US $10.00/KG
- Min. Order
- 100KG
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-12-06
- Product
- Phlorizin dihydrate 7061-54-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons/month
- Release date
- 2020-01-08