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Phlorizin dihydrate

Product Name
Phlorizin dihydrate
CAS No.
7061-54-3
Chemical Name
Phlorizin dihydrate
Synonyms
PHLORIDZIN;PHLORIDZIN(RG);TIMTEC-BB SBB005924;Phlorizin dihydrate;Phloridzin dihydrate 99%;phloridzin from apple wood;PHLORETIN-2'-BETA-D-GLUCOSIDE;Phlorizin dihydrate USP/EP/BP;Phloretin 2'-b-D-glucopyranoside;Phlorizin dihydrate, 10 mM in DMSO
CBNumber
CB3331802
Molecular Formula
C21H26O11
Formula Weight
454.43
MOL File
7061-54-3.mol
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Phlorizin dihydrate Property

Melting point:
113-114 °C(lit.)
alpha 
-52 º (c=3, EtOH)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Solid
color 
White to off-white
optical activity
[α]20/D 52°, c = 3 in ethanol
biological source
apple wood
BRN 
66621
CAS DataBase Reference
7061-54-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
UC2080000
3-10-23
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
274313
Product name
Phloridzin dihydrate
Purity
99%
Packaging
1g
Price
$166
Updated
2024/03/01
Sigma-Aldrich
Product number
274313
Product name
Phloridzin dihydrate
Purity
97%
Packaging
5g
Price
$477
Updated
2024/03/01
Sigma-Aldrich
Product number
P3449
Product name
Phloridzin dihydrate
Purity
from apple wood, ≥99% (HPLC)
Packaging
100mg
Price
$58.2
Updated
2024/03/01
Sigma-Aldrich
Product number
P3449
Product name
Phloridzin dihydrate
Purity
from apple wood, ≥99% (HPLC)
Packaging
500mg
Price
$76.2
Updated
2024/03/01
Sigma-Aldrich
Product number
P3449
Product name
Phloridzin dihydrate
Purity
from apple wood, ≥99% (HPLC)
Packaging
1g
Price
$142
Updated
2024/03/01
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Phlorizin dihydrate Chemical Properties,Usage,Production

Uses

Phloridzin dihydrate has been used as:

  • a Na+-glucose cotransport inhibitor to test its effect in lowering blood glucose
  • a hexose carrier inhibitor to prevent glucose derivative 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) uptake in sycamore cells
  • a non-specific sodium-glucose co-transporter 2 (SGLT2) inhibitor in embryonic cardiomyocyte cell line H9C2 to investigate its protective effect on Dox-induced cytotoxicity

Biochem/physiol Actions

Phloridzin is a glycoside present in the leaves and bark of apple. It is also present in peel and pulp of the apple fruit. Phloridzin belongs to the dihydrochalcones class of compounds. Lactase catabolizes phloridzin to phloretin and glucose in small intestine epithelial cells. Phloridzin is an antidiabetic agent and is equally bioavailable as phloretin.

target

NO | PGE | NOS | COX

Phlorizin dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Phlorizin dihydrate Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
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View Lastest Price from Phlorizin dihydrate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Phlorizin dihydrate 7061-54-3
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-12-06
Career Henan Chemical Co
Product
Phlorizin dihydrate 7061-54-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10 tons/month
Release date
2020-01-08

7061-54-3, Phlorizin dihydrateRelated Search:


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