Identification Description Regulatory Status Usage Natural occurrence
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Diallyldisulfide

Identification Description Regulatory Status Usage Natural occurrence
Product Name
Diallyldisulfide
CAS No.
2179-57-9
Chemical Name
Diallyldisulfide
Synonyms
DIALLYL DISULFIDE;DIALLYL DISULPHIDE;ALLYL DISULFIDE;DADS;ALLYL DISULPHIDE;Dially disulfide;1,2-diallyldisulfane;FEMA 2028;Disulfide,di-2-propenyl;garlicin oil
CBNumber
CB3337107
Molecular Formula
C6H10S2
Formula Weight
146.27
MOL File
2179-57-9.mol
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Diallyldisulfide Property

Boiling point:
180-195 °C(lit.)
Density 
1.008 g/mL at 25 °C(lit.)
vapor density 
>5 (vs air)
vapor pressure 
1 mm Hg ( 20 °C)
refractive index 
n20/D 1.541(lit.)
FEMA 
2028 | ALLYL DISULFIDE
Flash point:
144 °F
storage temp. 
2-8°C
Water Solubility 
Insoluble in water
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
oil
color 
colorless to yellow
Odor
Diallyl disulfide is an essential odor component of garlic oil.
Odor Threshold
0.00022ppm
Odor Type
alliaceous
JECFA Number
572
BRN 
1699241
InChIKey
PFRGXCVKLLPLIP-UHFFFAOYSA-N
LogP
3.26
CAS DataBase Reference
2179-57-9(CAS DataBase Reference)
NIST Chemistry Reference
Diallyl disulphide(2179-57-9)
EPA Substance Registry System
Diallyl disulfide (2179-57-9)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-10
Safety Statements 
26-36/37/39-37/39-16-36
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
3
RTECS 
BB1000000
13
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29309090
Hazardous Substances Data
2179-57-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W202800
Product name
Allyl disulfide
Purity
≥80%, FG
Packaging
100g
Price
$88.6
Updated
2024/03/01
Sigma-Aldrich
Product number
W202800
Product name
Allyl disulfide
Purity
≥80%, FG
Packaging
1kg
Price
$422
Updated
2024/03/01
Sigma-Aldrich
Product number
W202800
Product name
Allyl disulfide
Purity
≥80%, FG
Packaging
5kg
Price
$1230
Updated
2024/03/01
Sigma-Aldrich
Product number
317691
Product name
Allyl disulfide
Purity
technical grade, 80%
Packaging
25g
Price
$69.7
Updated
2024/03/01
Sigma-Aldrich
Product number
30648
Product name
Diallyl disulfide
Purity
analytical standard
Packaging
1ML
Price
$129
Updated
2022/05/15
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Diallyldisulfide Chemical Properties,Usage,Production

Identification

CAS.No.: 
2179-57-9 
FL.No.: 
12.008
FEMA.No.: 
2028
NAS.No.: 
2028
CoE.No.: 
485
EINECS.No.: 
218-548-6 
JECFA.No.: 
572
 
 

Description

Allyl disulfide has a characteristic garlic odor. It is used as a flavor enhancer, flavoring agent or adjuvant.

Regulatory Status

CoE: Used provisionally. Food: 5 ppm
FDA: 21 CFR 172.515
FDA (other): n/a
JECFA: ADI: Acceptable. No safety concern at current levels of intake when used as a flavoring agent (1999).

Usage

Reported uses (ppm): (FEMA, 1994)

Food Category 
Usual 
Max. 
Alcoholic beverages 
0.1
1
Baked goods 
9.09
13.16
Condiments, relishes 
13.82
15.21
Frozen dairy 
0.1
1
Gelatins, puddings 
0.5
1
Gravies 
2
6.5
Meat products 
9.4
13.1
Nonalcoholic beverages 
0.07
0.68
Soft candy 
0.5
1
Soups 
1
10

Natural occurrence

Main constituent of Allium sativum essential oil. Reported found in onion (Allium cipa, L.), garlic (Allium sativum L.), chive (Allium schoenoprasum L.), nira (Allium tuberosum rottl.), raw cabbage and caucas (Allium victoralis L.).

Description

Diallyl disulfide is one of the major allergens in garlic (Al/ium sativum) and onions. Among patients who are patch-test positive to garlic, all 13 who were tested had positive reactions to diallyl sulfide 5% petrolatum.

Chemical Properties

CLEAR YELLOW LIQUID

Chemical Properties

Allyl disulfide has a characteristic garlic odor. It is used as a flavor enhancer, flavoring agent or adjuvant

Occurrence

Main constituent of Allium sativum essential oil. Reported found in onion (Allium cipa, L.), garlic (Allium sativum L.), chive (Allium schoenoprasum L.), nira (Allium tuberosum rottl.), raw cabbage and caucas (Allium victoralis L.).

Uses

antineoplastic, antibacterial, apoptosis inducer, insecticide

Uses

Diallyl disulfide is one of the three principallow-molecular-weight allergens of garlic. Allylpropyl disulfide and allicin are the other allergens.

Uses

Diallyldisulfide has a range of uses varying from a Cytocrome P450 inhibitor to vasorelaxant and hypotensive. Being in the class of organosulfur compounds, it carries chemopreventive characteristics .

Definition

ChEBI: An organic disulfide where the organic group specified is allyl. It has been isolated from garlic and other species of the genus Allium.

Preparation

By oxidation of allyl mercaptan with iodine in the presence of pyridine and ethanol; from sodium allyl thiosulfate with potassium hydroxide.

Aroma threshold values

Detection: 4.3 to 30 ppb; Recognition: 80 ppb

Taste threshold values

Taste characteristics at 2 ppm: green onion and garlic-like with meaty nuances

Synthesis Reference(s)

The Journal of Organic Chemistry, 31, p. 615, 1966 DOI: 10.1021/jo01340a520
Synthetic Communications, 25, p. 3573, 1995 DOI: 10.1080/00397919508015492

General Description

Allyl disulfide is naturally found in Allium species such as garlic and onion. It is used as a flavoring agent in meat and condiments.

Contact allergens

Diallyldisulfide is one of the major allergens in garlic (Allium sativum) and onions. Among patients patch-testpositive to garlic, all 13 who were tested had positive reactions to diallyl sulfide 5% pet.

Biochem/physiol Actions

Organosulfur compound that is naturally found in garlic. Contributes to the pungent odor of crushed garlic. Anticancer agent and may provide protection against cardiovascular disease.

Purification Methods

Purify the disulfide by fractional distillation until the molar refractivity is in uniformly good agreement with the calculated value [Small et al. J Am Chem Soc 69 1710 1947]. It has also been purified by gas chromatography [retention times: Carson & Wong J Org Chem 24 175 1959, UV: Koch J Chem Soc 395 1949]. It is present in garlic. [Beilstein 1 IV 2098.]

Diallyldisulfide Preparation Products And Raw materials

Raw materials

Preparation Products

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Diallyldisulfide Suppliers

Shanghai Chang-Gen Chemical Technology Co., Ltd.
Tel
021-69106814 13917161715
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3007500651@qq.com
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China
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Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
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China
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
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jkinfo@jkchemical.com
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3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
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3bsc@sina.com
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China
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future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
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China
ProdList
1995
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Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
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saleschina@alfa-asia.com
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China
ProdList
30123
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
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Energy Chemical
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021-021-58432009 400-005-6266
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JinYan Chemicals(ShangHai) Co.,Ltd.
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Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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Country
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ProdList
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View Lastest Price from Diallyldisulfide manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Allyl Disulfide 2179-57-9
Price
US $180.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-28
Hebei Weibang Biotechnology Co., Ltd
Product
Diallyldisulfide 2179-57-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-01
Hebei Yanxi Chemical Co., Ltd.
Product
Diallyldisulfide 2179-57-9
Price
US $50.00-35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
15 tons
Release date
2024-02-27

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