5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL

Product Name: 5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL
CAS No.: 83002-04-4
Chemical Name: 5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL
Synonyms: CP 55667;CP55,667;CP-55667;CP 55,940;CP-55940 (CP 55,940);(-)-Cis-3-[2-Hydroxy-4-(1,1-Di;(-)-CP 55940 (10 mg/mL in methanol);(-)-CP 55,940 (10 mg/mL in methanol);(-)-cis-3-[2-Hydroxy-4-(1,1-diMethy lheptyl)ph;5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL
CBNumber: CB3344402
Molecular Formula: C24H40O3
Formula Weight: 376.57
MOL File: 83002-04-4.mol

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5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL Property

Melting point:: 65-68 °C
Boiling point:: 494.4±45.0 °C(Predicted)
Density: 1.026±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: 15 mg/mL, soluble
form: solid
pka: 10.25±0.40(Predicted)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H336May cause drowsiness or dizziness

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C1112
Product name: CP-55940
Purity: >98% (HPLC), powder
Packaging: 10mg
Price: $301
Updated: 2024/03/01

Sigma-Aldrich

Product number: C1112
Product name: CP-55940
Purity: >98% (HPLC), powder
Packaging: 50mg
Price: $1230
Updated: 2024/03/01

Sigma-Aldrich

Product number: 5.04316
Product name: CP-55940 - CAS 83002-04-4 - Calbiochem
Packaging: 5mg
Price: $166
Updated: 2022/05/15

Cayman Chemical

Product number: 90084
Product name: (-)-CP 55,940
Purity: ≥98%
Packaging: 1mg
Price: $117
Updated: 2024/03/01

Cayman Chemical

Product number: 90084
Product name: (-)-CP 55,940
Purity: ≥98%
Packaging: 5mg
Price: $464
Updated: 2024/03/01

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5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL Chemical Properties,Usage,Production

Uses

CP 55,940 is a cannabinoid agonist which is considerably more potent than Δ9-THC in both behavioral tests and receptor binding assays. Displays high and roughly equal affinity for both central and peripheral cannabinoid receptors (Ki = 0.6 - 5.0 and 0.7 - 2.6 nM at CB1 and CB2 respectively; EC50 values are 0.2, 0.3 and 5 nM at CB1, CB2 and GRP55 respectively). Controlled substance.

Uses

CP-55940 has been used as a cannabinoid agonists in Chinese hamster ovary (CHO) expressing cannabinoid receptor 2(CB2).

Uses

(+)-CP 55940 is the enantiomer of (C781415), a cannabinoid agonist. Both CP 55,940 and (+)-CP 55940 bind to CB receptors but only CP-55,940 elicits a biological response via the receptors. However, ( +)-CP 55940 shows the same antinociceptive effects as its enantiomer.

Definition

ChEBI: 2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol is an alkylbenzene and a ring assembly.

Biological Activity

Cannabinoid agonist which is considerably more potent than Δ 9 -THC in both behavioral tests and receptor binding assays. Displays high and roughly equal affinity for both central and peripheral cannabinoid receptors (K i = 0.6-5.0 and 0.7-2.6 nM at CB 1 and CB 2 respectively; EC 50 values are 0.2, 0.3 and 5 nM at CB 1 , CB 2 and GRP55 respectively). Also available as part of the Cannabinoid Receptor Agonist Tocriset™ .

Biochem/physiol Actions

CP-55940 is a nonclassical cannabinoids (NCCs), which lack the tetrahydropyran ring. CP-55940, a derivative of CP-47,497 is enantioselective. Due to its amphipathic nature, CP-55940 tethers in biological membrane making it favourable for the cannabinoid receptor interaction. CP-55940 belongs to the cyclohexylphenol category and modulates the brain lipidome leading to dysregulation especially during adolescence. It inhibits capsaicin-evoked sensitization of nociceptive and spinal dorsal horn neurons.

5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL Suppliers

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View Lastest Price from 5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL manufacturers

Career Henan Chemical Co

Product: 5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL 83002-04-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-03-11

83002-04-4, 5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOLRelated Search:

AM 251 ACEA AM 630 2-AG BML-190 ACPA R(+)-ARACHIDONYL-1'-HYDROXY-2'-PROPYLAMIDE ARACHIDONIC ACID-(2-AMINOETHYL)-ESTER HYDROCHLORIDE MEAD ACID ETHANOLAMIDE ARACHIDONAMIDE Cyclohexanol 2,5-DIISOPROPYLPHENOL Methyl salicylate 5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL 3-(4-TERT-BUTYL-PHENYL)-PROPAN-1-OL 5-TERT-BUTYL-2-METHYLPHENOL 2-CYCLOHEXYL-5-METHYLPHENOL 3-(4-ISOPROPYL-PHENYL)-PROPAN-1-OL

CP 55,940

(-)-CIS-3-[2-HYDROXY-4-(1,1-DIMETHYLHEPTYL)PHENYL]-TRANS-4-(3-HYDROXYPHENYL) CYCLOHEXANOL

(-)-CIS-3-[2-HYDROXY-4-(1,1-DIMETHYLHEPTYL)PHENYL]-TRANS-4-(3-HYDROXYPROPYL)CYCLOHEXANOL

5-(1,1-DIMETHYLHEPTYL)-2-[5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL

(-)-Cis-3-[2-Hydroxy-4-(1,1-Di

(1R)-3β-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-4α-(3-hydroxypropyl)cyclohexane-1β-ol

3β-[4-(1,1-Dimethylheptyl)-2-hydroxyphenyl]-4α-(3-hydroxypropyl)cyclohexan-1β-ol

5-(1,1-DIMETHYLHEPTYL)-2-[(1R,2R,5R)-5-HYDROXY-2-(3-HYDROXYPROPYL)CYCLOHEXYL]PHENOL

2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-Methyloctan-2-yl)phenol

(-)-cis-3-[2-Hydroxy-4-(1,1-diMethy lheptyl)ph

(1α,2β,5α)-(-)-5-(1,1-DiMethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl) cyclohexyl]phenol

Phenol,5-(1,1-diMethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-

(-)-CP 55940 (10 mg/mL in methanol)

(-)-CP 55,940 (10 mg/mL in methanol)

CP-55940 (CP 55,940)

CP 55667

CP55,667

CP-55667

83002-04-4

Cannabinoid receptor

Aromatics

Chiral Reagents

Intermediates & Fine Chemicals

Pfizer Compounds

Pharmaceuticals