4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

ChemicalBook > CAS DataBase List > 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

Product Name: 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
CAS No.: 21561-09-1
Chemical Name: 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
Synonyms: WHI-P258;JAK3 INHIBITOR, NEGATIVE CONTROL;4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE;6,7-DIMETHOXY-N-PHENYL-4-QUINAZOLINAMINE;6,7-dimethoxy-N-phenylquinazolin-4-amine;4-Quinazolinamine, 6,7-dimethoxy-N-phenyl-;N-(6,7-DIMETHOXY-4-QUINAZOLINYL)-N-PHENYLAMINE;JAK3 INHIBITOR NEGATIVE CONTROL;WHIP258;WHI P258;WHI P258,WHI-P258,inhibit,Inhibitor,JNK,WHI-P-258,WHIP258
CBNumber: CB3348071
Molecular Formula: C16H15N3O2
Formula Weight: 281.31
MOL File: Mol file

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4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Property

Boiling point:: 441.2±40.0 °C(Predicted)
Density: 1?+-.0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml
form: A crystalline solid
pka: 6.19±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23453
Product name: WHI-P258
Purity: ≥98%
Packaging: 10 mg
Price: $118
Updated: 2024/03/01

Cayman Chemical

Product number: 23453
Product name: WHI-P258
Purity: ≥98%
Packaging: 25 mg
Price: $202
Updated: 2024/03/01

Cayman Chemical

Product number: 23453
Product name: WHI-P258
Purity: ≥98%
Packaging: 500μg
Price: $103
Updated: 2023/01/06

Cayman Chemical

Product number: 23453
Product name: WHI-P258
Purity: ≥98%
Packaging: 1mg
Price: $186
Updated: 2023/01/06

Cayman Chemical

Product number: 23453
Product name: WHI-P258
Purity: ≥98%
Packaging: 5mg
Price: $74
Updated: 2024/03/01

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4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Chemical Properties,Usage,Production

Description

WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated K_i value of 72 μM. However, it is inactive at JAK3 (IC₅₀ = >300 μM) and has been used as a negative control for structurally similar compounds that inhibit platelet aggregation and herpes simplex virus 1 (HSV-1) replication.

Uses

4-Phenylamino-6,7-dimethoxyquinazoline is a specific inhibitors of Janus kinase 3 (JAK3).

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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21561-09-1, 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINERelated Search:

4-(3'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE, HCL WEHI-345 JAK3 INHIBITOR I 4-AMINO-3-CYANO-1,2,5,6-TETRAHYDROPYRIDINE WH-4-023 7-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE WHI-P97 JAK3 Inhibitor Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-

WHI-P258

JAK3 INHIBITOR NEGATIVE CONTROL;WHIP258;WHI P258

4-Quinazolinamine, 6,7-dimethoxy-N-phenyl-

N-(6,7-DIMETHOXY-4-QUINAZOLINYL)-N-PHENYLAMINE

6,7-dimethoxy-N-phenylquinazolin-4-amine

JAK3 INHIBITOR, NEGATIVE CONTROL

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

6,7-DIMETHOXY-N-PHENYL-4-QUINAZOLINAMINE

WHI P258,WHI-P258,inhibit,Inhibitor,JNK,WHI-P-258,WHIP258

21561-09-1

Inhibitors