3-BROMO-4-FORMYLPYRIDINE

Product Name: 3-BROMO-4-FORMYLPYRIDINE
CAS No.: 70201-43-3
Chemical Name: 3-BROMO-4-FORMYLPYRIDINE
Synonyms: 3-BROMOISONICOTINALDEHYDE;CHEMBRDG-BB 4003258;3-BROMO-4-FORMYLPYRIDI;3-BROMO-4-FORMYLPYRIDINE;3-Bromoisonicotinaldehyde 95%;3-Bromoisonicotinaldehyde ,98%;3-Bromo-4-pyridinecarbaldehyde;3-BROMO-PYRIDINE-4-CARBALDEHYDE;3-BROMO-4-PYRIDINECARBOXALDEHYDE;5-BroMopyridine-4-carboxaldehyde
CBNumber: CB3351242
Molecular Formula: C6H4BrNO
Formula Weight: 186.01
MOL File: 70201-43-3.mol

More

Less

3-BROMO-4-FORMYLPYRIDINE Property

Melting point:: 81-82 °C(lit.)
Boiling point:: 246.2±20.0 °C(Predicted)
Density: 1.683±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Acetonitrile (Slightly), Chloroform (Slightly)
form: Solid
pka: 0.90±0.18(Predicted)
color: Light Brown
InChIKey: NOBDKWLIAQKADB-UHFFFAOYSA-N

More

Less

Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/38-43
Safety Statements: 26-36/37
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29333990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 638285
Product name: 3-Bromo-4-pyridinecarboxaldehyde
Purity: 97%
Packaging: 5g
Price: $209
Updated: 2025/07/31

Sigma-Aldrich

Product number: 638285
Product name: 3-Bromo-4-pyridinecarboxaldehyde
Purity: 97%
Packaging: 1g
Price: $77.8
Updated: 2023/01/07

TCI Chemical

Product number: B2624
Product name: 3-Bromopyridine-4-carboxaldehyde
Packaging: 1G
Price: $40
Updated: 2025/07/31

TCI Chemical

Product number: B2624
Product name: 3-Bromopyridine-4-carboxaldehyde
Packaging: 5G
Price: $158
Updated: 2025/07/31

TRC

Product number: B688825
Product name: 3-Bromo-4-pyridinecarboxaldehyde
Packaging: 1g
Price: $45
Updated: 2021/12/16

More

Less

3-BROMO-4-FORMYLPYRIDINE Chemical Properties,Usage,Production

Chemical Properties

Off-white solid

Uses

3-Bromo-4-pyridinecarboxaldehyde acts as a reagent in the synthesis of 3,4,5-trisubstituted 4,5-dihydro-1,2,4-oxadiazoles agonists which interact with the G-protein-coupled bile acid receptor 1 (TGR5) inducing insulin secretion which may be used as a potential treatment for diabetus mellitus.

Synthesis

626-55-1

68-12-2

70201-43-3

Diisopropylamine (27.6 g, 273.0 mmol) was dissolved in tetrahydrofuran (300 mL) under nitrogen protection and cooled to -78 °C. A tetrahydrofuran solution of n-butyllithium (91 mL, 228.0 mmol, 2.5 M) was slowly added dropwise and stirred at -78 °C for 1 hour. Subsequently, 3-bromopyridine (30.0 g, 190.0 mmol) was added dropwise and stirring was continued at -78 °C for 20 min. Next, N,N-dimethylformamide (55.0 g, 760.0 mmol) was added dropwise and stirred at -78 °C for 1 hour. After completion of the reaction, the mixture was slowly warmed to room temperature and the reaction was quenched with saturated aqueous ammonium chloride solution (150 mL). The aqueous layer was extracted with ethyl acetate (200 mL x 3), and the organic layers were combined and concentrated in vacuum. The residue was purified by silica gel column chromatography to afford 3-bromopyridine-4-aldehyde (12.0 g, 34.0% yield). The product was confirmed by 1H NMR (400 MHz, CD3OD): δ 10.37 (s, 1H), 8.91 (s, 1H), 8.80-8.61 (m, 1H), 7.78-7.63 (m, 1H).LCMS (m/z): 187.0 (M + 1).

References

[1] Tetrahedron, 2000, vol. 56, # 3, p. 397 - 406
[2] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 11, p. 3146 - 3151
[3] Patent: WO2015/200677, 2015, A2. Location in patent: Paragraph 00504; 00505
[4] Tetrahedron Letters, 1983, vol. 24, # 32, p. 3291 - 3294
[5] Synthesis, 1999, # 2, p. 306 - 311

3-BROMO-4-FORMYLPYRIDINE Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide Diisopropylamine Tetrahydrofuran Ethyl acetate 3-Pyridyl bromide n-Butyllithium

Preparation Products

More

Less

3-BROMO-4-FORMYLPYRIDINE Suppliers

Americas 1 Belgium 1 China 183 Europe 1 France 2 Germany 7 India 11 Japan 1 Slovakia 1 Switzerland 4 Ukraine 1 United Kingdom 10 United States 45 Global 268

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 50000
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Ark Pharm, Inc.

Tel: 847-367-3680
Fax: 847-367-3681
Email: sales@arkpharminc.com
Country: United States
ProdList: 1670
Advantage: 56

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Changzhou Huanling Chemical Co., Ltd.

Tel: 0519-89803565 13776850645
Fax: 0519-89803575
Email: info4@huanlingchem.com
Country: China
ProdList: 891
Advantage: 68

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

More

Less

View Lastest Price from 3-BROMO-4-FORMYLPYRIDINE manufacturers

Dideu Industries Group Limited

Product: 3-BROMO-4-FORMYLPYRIDINE 70201-43-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-18

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Bromopyridine-4-carboxaldehyde 70201-43-3
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-12

Career Henan Chemical Co

Product: 3-BROMO-4-FORMYLPYRIDINE 70201-43-3
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: Customized
Release date: 2018-12-14

70201-43-3, 3-BROMO-4-FORMYLPYRIDINERelated Search:

3-BROMO-2-FORMYLPYRIDINE 4-Bromo-3-formylpyridine hyrdobromide salt 2-FORMYL-5-BROMOPYRIDINE / 5-BROMO-2-FORMYLPYRIDINE,5-BROMO-2-FORMYLPYRIDINE,5-Bromo-2-formylpyridine, 5-Bromo-2-picolinaldehyde 6-BROMO-2-FORMYLPYRIDINE,2-BROMO-6-FORMYLPYRIDINE 2-Bromopyridine-3-carboxaldehyde, 2-Bromo-3-formylpyridine,2-BROMO-3-FORMYLPYRIDINE 2-BROMO-4-FORMYLPYRIDINE 5-Bromo-3-formylpyridine 5-BROMO-3-METHYL-2-PYRIDINECARBALDEHYDE 2-BROMO-5-FORMYLPYRIDINE,2-BROMO-5-FORMYLPYRIDINE97+% ,5-Dihydro-5-methyl-6-[4-(4-oxo-1(4H)-pyridinyl)phenyl]-1,2,4-triazin-3(2H)-one 4-BROMO-3-FORMYLPYRIDINE

3-Bromoisonicotinaldehyde ,98%

3-Bromopyridine-4-carboxaldehyde ,98%

3-Bromoisonicotinaldehyde 95%

5-BroMopyridine-4-carboxaldehyde

CHEMBRDG-BB 4003258

3-BROMO-4-PYRIDINECARBOXALDEHYDE

3-BROMO-4-FORMYLPYRIDINE

3-BROMO-PYRIDINE-4-CARBALDEHYDE

3-BROMOPYRIDINE-4-CARBOXALDEHYDE

3-BROMOISONICOTINALDEHYDE

3-Bromopyridine-4-carboxaldehyde 95%

3-Bromo-4-pyridinecarbaldehyde

4-Pyridinecarboxaldehyde, 3-bromo-

3-BROMO-4-FORMYLPYRIDINE ISO 9001：2015 REACH

3-BROMO-4-FORMYLPYRIDI

70201-43-3

70201-43-2

Pyridines

Heterocyclic Building Blocks

Halogenated Heterocycles

Building Blocks

C1 to C6

C5 to C6

C6 to C7

Carbonyl Compounds

Chemical Synthesis

Halogenated Heterocycles

Heterocyclic Building Blocks

pharmacetical

Aldehydes

Pyridines

Pyridine

Building Blocks

Halogenated

C6Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Organic Building Blocks